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Be APOL1 Aware and Understand How Genes Impact Kidney Health

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APOL1

(Family Features) Senior year of high school is a time for big changes for most people, but for Emani McConnell-Brent, she did not expect it would include changes to her health. After being rushed to the emergency room with severe stomach pain, McConnell-Brent learned the problem was her kidneys and she was diagnosed with a kidney disease called focal segmental glomerulosclerosis (FSGS).

After her diagnosis, McConnell-Brent struggled to get the right medicines to treat her disease. She was encouraged to undergo a genetic test and discovered her FSGS was the result of APOL1-mediated kidney disease (AMKD), a rapidly progressive genetic kidney disease that can cause kidney failure. The diagnosis brought McConnell-Brent some relief, both physically and emotionally.

“Knowing it’s genetic and knowing I’m taking care of myself makes a big difference in my mental state,” said McConnell-Brent, now 21 and an ambassador for the American Kidney Fund.

17428 detail image embed1Everyone has two copies of the apolipoprotein L1 (APOL1) gene – one from each parent – but Black Americans of West and Central African ancestry are more likely to have changes (variants or mutations) in their APOL1 gene that cause AMKD. This genetic form of kidney disease can develop even at a young age, in otherwise healthy people, and can advance faster than other kidney diseases.

An estimated 13% of Black Americans have the two APOL1 gene variants that are associated with AMKD. Those who have variants in both copies of the APOL1 gene have a 1 in 5 chance of developing kidney disease.

“A lot of people don’t even know about how prevalent the APOL1 gene is in the African American community,” McConnell-Brent said.

Early diagnosis of AMKD can keep your kidneys working longer, delaying the need for dialysis or a kidney transplant.

If you have kidney damage, symptoms may not occur until your kidneys are close to failing. As kidney damage worsens, one or more of these symptoms may occur:

  • Protein in urine
  • Swelling in legs or weight gain
  • Feeling weak or tired
  • High blood pressure

The only way to get an official diagnosis for AMKD is through a genetic test. You can find more information about the risks and benefits of genetic testing online.

“If you got genetic testing, you would have the facts of what your genes are telling you,” McConnell-Brent said. “Your genes are telling you a story of what did happen, is happening and could happen.”

This AMKD Awareness Day, on April 29, become APOL1 Aware by learning how your genes impact your kidney health and help build awareness in your community by visiting KidneyFund.org/APOL1Aware.

 

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American Kidney Fund

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Lifestyle

Small Business Month: Celebrating the Entrepreneurs Powering America

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Last Updated on May 16, 2026 by Daily News Staff

people working in an office. Small Business Month
Photo by Alena Darmel on Pexels.com

National Small Business Month

Every May, communities across the United States recognize Small Business Month, a time dedicated to celebrating the entrepreneurs, family-owned companies, startups, and local shops that help drive the American economy. From neighborhood restaurants to innovative tech startups, small businesses continue to play a vital role in creating jobs, supporting communities, and inspiring innovation.

Shop Local

According to the U.S. Small Business Administration, small businesses account for millions of jobs nationwide and represent the backbone of local economies. Throughout May, organizations, chambers of commerce, and business leaders host networking events, educational workshops, and promotional campaigns to support entrepreneurs and encourage consumers to shop locally.

One of the highlights of the month is National Small Business Week, which honors outstanding entrepreneurs and business owners making a difference in their communities.

For consumers, Small Business Month is also a reminder that supporting local businesses helps strengthen neighborhoods and keeps communities thriving. Whether it’s dining at a local café, shopping at an independent store, or hiring a local service provider, every purchase can make an impact.

Learn more about Small Business Month and related events through the official U.S. Small Business Administrationwebsite.

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Cruise travel is having more than a moment. It’s having a decade.

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Cruise travel is having more than a moment. It's having a decade.

Cruise travel is having more than a moment. It’s having a decade.

(Tiffany Miller) The cruise industry is not waiting for travelers to come around. By most measures, they already have. A projected 21.7 million Americans are expected to cruise in 2026, a record high and a 4.5 percent increase over last year, according to AAA.

“Cruising has come a long way since The Love Boat,” said writer and travel expert Sarah Greaves-Gabbadon, aka JetSetSarah. “Pull up to the port, unpack once and have the world come to you.” 

This April, more than 11,500 attendees and 650 exhibitors gathered at Seatrade Cruise Global to map out what comes next.

Dining as the main event

Food has always been part of the cruise experience. The question the industry is now asking is what happens when it becomes the point.

Cruise lines are placing greater emphasis on the dining experience, with destination-inspired menus, port-specific drinks and more immersive, multi-course experiences. 

Royal Caribbean introduced the Empire Supper Club this year, pairing multi-course menus with craft cocktails and live music into a single evening.

Expedition cruising finds a new audience

Expedition cruising is one of the fastest-growing types of cruising, and major cruise lines are moving into it.

These itineraries go where other ships do not. Travelers kayak among glaciers, contribute to citizen science programmes and spend time in the field with naturalists and researchers, with programming built around science and conservation rather than port stops.

National Geographic-Lindblad Expeditions has operated in this space for decades, with programs including the Visiting Scientist Program, the Lindblad Expeditions-National Geographic Fund and the Grosvenor Teacher Fellowship.

Wellness expands across the ship

Wellness is no longer a spa deck. It is becoming a reason to book.

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A few years ago, a thermal suite was a selling point. Now it is closer to a baseline expectation. Meditation spaces, sleep-focused staterooms and recovery lounges are following the same trajectory. A dedicated wellness pavilion debuted at this year’s show, a signal that the category has grown large enough to need its own floor space.

Cunard’s Wellness at Sea program runs across multiple days. Its three tracks (Relax, Energise and Recover) each combine fitness, spa and mindfulness elements. Shore excursions and destination-specific spa offerings carry the experience beyond the ship.

Ships as cultural hubs

Entertainment on cruise ships used to mean a stage show. Cruise lines are now producing content that doesn’t exist anywhere else.

Holland America Line partnered with The Verdon Fosse Legacy to debut “Fosse and Verdon, The Duet That Changed Broadway,” a live musical and multimedia tribute to the work of Bob Fosse and Gwen Verdon. The production marks the first international staging of their work at sea.

Onboard retail is moving in the same direction. More cruise lines are curating locally sourced goods and destination-specific products at port, the kind passengers could only find by actually being there.

The bigger picture

The passenger numbers tell one part of the story. What cruise lines are building inside that growth tells another.

“Today’s ships offer amenities that are at least as good as, and often more comprehensive than, those in resorts and hotels,” Greaves-Gabbadon said. “A cruise can be equally enjoyable for solos, families, honeymooners, groups and adventurers, and that versatility is a large part of their appeal.”

What the show floor made clear is that the industry is not waiting to be discovered. It is building toward the traveler it wants next.

Photo courtesy of Shutterstock

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SOURCE:

Seatrade Cruise Global

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Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/

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Navigating Travel Plans: When Travel Advisors Can Take You Further Than AI

Travel Advisors: From comparing prices to dreaming up bucket-list destinations, artificial intelligence has become a starting point for millions of travelers who are turning to tech for early-stage planning. However, travelers consistently emphasize the importance of having accessible expert support during the process.

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Navigating Travel Plans: When Travel Advisors Can Take You Further Than AI

Navigating Travel Plans: When Travel Advisors Can Take You Further Than AI

(Feature Impact) From comparing prices to dreaming up bucket-list destinations, artificial intelligence has become a starting point for millions of travelers who are turning to tech for early-stage planning.

However, travelers consistently emphasize the importance of having accessible expert support during the process. In fact, 96% of U.S. travelers said having access to a human for support is important when booking a vacation, according to a new survey commissioned by ALG Vacations, a leading provider of vacation packages to top global destinations, including 48% who said it’s “extremely” important.

Though 24% of survey respondents said the main way they use AI is for comparing prices or finding travel deals, 63% of Americans said they trust a travel advisor as much as or more than AI tools when planning a vacation, underscoring that AI alone is not enough for most U.S. travelers. Going beyond the planning phase, 77% of survey respondents said that even if they use AI for travel planning, they’re still likely to rely on a human to make final decisions, especially for booking, payment or resolving issues.

In honor of Travel Advisor Appreciation Month, consider these ways travelers can take advantage of the expertise of an advisor to get the most out of every trip.

Navigating Travel Uncertainty

Today’s travel landscape can feel unpredictable, from shifting policies to headlines that make things feel bigger or closer than they actually are, but that doesn’t mean travelers should avoid taking the trip; it just means they should plan smarter. Because 42% of travelers fear important details could be missed if relying entirely on AI to plan a trip, that’s where a travel advisor comes in to help separate what’s real from what’s just noise. This expertise allows for smarter, more confident decisions, and aids in choosing destinations that align with travelers’ current comfort levels.

Unlocking Added Value

17929 detail embed2

Planning thoughtfully doesn’t mean spending more, it means getting more for the amount spent. Travel advisors often have access to exclusive perks and upgrades not directly available to consumers or pulled in by AI prompts, providing added value that goes beyond the cost of the vacation. In addition to added amenities, advisors’ insider recommendations can help match those perks to travelers’ preferences.

In fact, for vacations booked during the month of May, travelers can take advantage of The Great Getaway Savings Event from ALG Vacations, which features up to $950 in savings through a combination of instant savings, promo codes, air credits and group offers on trips to destinations in the Caribbean, Mexico, Hawaii, the continental United States, Europe, Central America, Dominican Republic and the South Pacific.

Providing Protection and Peace of Mind

Modern travelers want options, and the ability to adjust plans, add protection or pivot when needed has become a top priority. A travel advisor can assist with adding that flexibility through travel protection that provides extra peace of mind – whether that means rebooking or changing plans if something comes up. At the end of the day, it’s about helping travelers feel prepared so they can relax and truly enjoy their vacations.

Stepping in When Things Go Awry

When trips become complex, multi-destination or disrupted by delays or cancellations, travelers are more likely to want a real person involved. In fact, 39% of survey respondents worry there will be no support if something goes wrong. If a flight is canceled or a resort overbooks, travelers aren’t stuck refreshing an app; they have an expert there every step of the way – before, during and after the trip – listening to them, learning about their preferences, advocating for them and providing guidance based on first-hand experience throughout the process.

For a one-stop-shop to help bring every stage of travel planning seamlessly together, visitTravelAdvisorsGetYouThere.com to find a travel advisor near you who can provide additional assistance with planning, booking and more.

Photos courtesy of Shutterstock

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SOURCE:

ALG Vacations

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Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.

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