health and wellness
How to Talk to Your Doctor About Statin Intolerance
Last Updated on October 5, 2025 by Daily News Staff
How to Talk to Your Doctor About Statin Intolerance
(Family Features) If your doctor has concerns about your cholesterol levels, you may be familiar with statins. This is a class of medications that can help reduce your body’s cholesterol production, lowering your risk of heart attack or stroke.
However, up to 30% of adults in the United States have some degree of statin intolerance, according to research published in the “Journal of Clinical Lipidology.” Possible signs or symptoms of statin intolerance are muscle aches and cramps, fatigue, weakness, elevated liver enzymes and the onset of diabetes or impaired glucose tolerance.
As a result, nearly one-third of patients (29%) discontinue their statin within the first year, according to findings published in the “American Journal of Cardiology.” Unfortunately, patients with statin intolerance are at an increased risk of cardiovascular disease, including higher rates of coronary heart disease and recurrent heart attack.
Lowering Bad Cholesterol
A diagnosis of high cholesterol involves measuring low-density lipoprotein (LDL) cholesterol, which is commonly referred to as “bad” cholesterol because it leads to the accumulation of plaque in your arteries. Plaque reduces your blood flow, which can cause damage to your cardiovascular system.
Bloodwork is the best indicator of your cholesterol levels, since you may not experience any symptoms of high cholesterol until you already have damage and buildup in your arteries.
To help create your treatment plan, talk to your doctor about your medical history, including whether you’ve had a heart attack or any heart procedures, such as a stent placement or bypass surgery. You’ll also review current medications, recent lab results and notes on any symptoms you may be experiencing.
Your doctor is likely to recommend a series of steps to reduce your cholesterol. Some common recommendations include a healthy diet low in saturated and trans fats and high in fiber, especially fruits, vegetables and whole grains.
If you’re not already getting regular physical activity, your doctor will likely encourage you to get at least 30 minutes of exercise daily, find ways to include more movement in your everyday lifestyle and, if necessary, work toward shedding extra weight.
Lifestyle changes can help but may not make a big enough impact to reduce cholesterol to a recommended level. In those cases, doctors rely on cholesterol-lowering medications such as statins. Statins can be highly effective at reducing bad cholesterol, making them a powerful tool to reduce the risks associated with heart disease.
When Statins Are Intolerable or Aren’t Enough
For a variety of reasons, including intolerance to the medication, other health conditions or interactions with other medications, statins may not be the right choice for everyone.
“While statins remain the gold standard for cholesterol lowering, I often see patients who either can’t or won’t take a statin, as well as patients who require further LDL cholesterol reduction,” said Guy L. Mintz, Director of Cardiovascular Health & Lipidolology at Northwell Health System. “For those patients, I prescribe non-statin medications, such as NEXLETOL (an oral prescription medication with the cholesterol lowering agent bempedoic acid) and NEXLIZET (a combination of cholesterol-lowering medicines bempedoic acid and ezetimibe). I am comfortable using NEXLETOL and NEXLIZET, along with a healthy diet and exercise, to reduce LDL cholesterol in adults with high blood cholesterol levels and to reduce risk of heart events. Non-statins are another important therapeutic tool in our lipid lowering toolbox.”
To learn more visit Nexlizet.com.
Photo courtesy of Shutterstock
IMPORTANT SAFETY INFORMATION
What are NEXLIZET tablets and NEXLETOL tablets?
- Along with a diet:
- NEXLETOL is used, with other cholesterol-lowering medicines, or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH).
- NEXLIZET is used, with or without other cholesterol-lowering medicines, to reduce low- density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).
- The bempedoic acid portion of NEXLIZET and NEXLETOL is used to lower the risk of heart attack and heart procedures like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
- have known heart disease, or
- are at high risk for heart disease but without known heart disease.
Do not take NEXLIZET if you are allergic to ezetimibe or bempedoic acid, or any ingredients in NEXLIZET or NEXLETOL. If you have any of the following signs and symptoms of a serious allergic reaction, call your healthcare provider or go to the nearest hospital emergency room:
- swelling of your face, lips, mouth, or tongue
- wheezing
- severe itching
- fast heartbeat or pounding in your chest
- trouble breathing
- skin rashes, redness, or swelling
- dizziness or fainting
What should I tell my healthcare provider before taking NEXLIZET or NEXLETOL? Tell your healthcare provider if you:
- have, or had, gout
- have or had tendon problems
- are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLIZET or NEXLETOL passes into your breastmilk
- have severe kidney or severe liver problems
Tell your healthcare provider about all the medicines you take, including prescription and over-the- counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you take or plan to take simvastatin or pravastatin, as taking either with bempedoic acid may increase your risk of developing muscle pain or weakness. If you take NEXLIZET, tell your doctor if you take cyclosporine, fibrates, or cholestyramine.
What is the most important safety information I should know about NEXLIZET and NEXLETOL? NEXLIZET and NEXLETOL can cause serious side effects, including:
- increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms: severe foot pain especially in the toe joint, warm joints, swelling, tender joints or joint redness.
- tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLIZET or NEXLETOL. The risk of getting tendon problems while you take NEXLIZET or NEXLETOL is higher if you: are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLIZET or NEXLETOL immediately and get medical help if you experience signs of tendon rupture such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area.
The most common side effects in people with primary hyperlipidemia:
- NEXLETOL includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia and increased liver enzymes.
- NEXLIZET includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, increased liver enzymes, diarrhea, joint pain, swelling of sinuses and fatigue.
The most common side effects of bempedoic acid, a component of NEXLIZET and NEXLETOL, in people with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.
These are not all the possible side effects of NEXLIZET and NEXLETOL. For more information, ask your healthcare provider or pharmacist for more information.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
SOURCE:
How Invasive Pests Spread and How You Can Help Stop Them
(Feature Impact) Invasive pests can hide in places you’d never expect, and once they spread, they can destroy the trees, plants and food people rely on every day. These pests pose a serious threat to agriculture, forests, ecosystems and the food supply. Many invasive species cannot travel far on their own; instead people unknowingly move them from place to place.
According to the U.S. Department of Agriculture’s Animal and Plant Health Inspection Service, invasive pests hitchhike on everyday items such as plants, produce, firewood, vehicles and outdoor equipment. That makes many common activities – from traveling and online shopping to camping and gardening – potential “pathways” for invasive pests to move and reach new areas. Understanding these pathways is the first step to stopping pests before they spread.
Traveling Abroad
When you travel abroad and return from another country, the agricultural items you bring back can introduce new invasive pests into the U.S. and threaten crops or trees that have no natural defenses against them. Even harmless-looking fruit, seed packets or souvenirs made with plant materials can carry pests such as fruit flies and diseases like citrus canker. That’s why it’s critical travelers declare food, plants and other agricultural products when entering the country from abroad.
Shopping Online
Just because you can order seeds and plants from sellers around the world, it doesn’t mean those items are legal or safe to import. In fact, some invasive snails and plant diseases have entered the U.S. this way. Many agricultural products from overseas require permits, inspections or special paperwork before they can enter the country. Buyers should check where an item ships from, learn the import requirements before purchasing and make sure sellers follow all labeling and shipping rules.
Partaking in Outdoor Activities
When you spend time outdoors hiking, camping, hunting or fishing, you could inadvertently spread invasive species. For example, transporting firewood from one location to another can spread tree-killing insects, such as the emerald ash borer, which can live inside the wood and emerge later in a new area. The safest choice is to buy or use firewood where you burn it. Additionally, clean all outdoor clothing, gear, equipment and vehicles before leaving an area.
Moving Outdoor Equipment
When you move to a new home, your move can create another opportunity for invasive insects to travel. Before relocating patio furniture, grills, trailers or lawn equipment, inspect and clean them carefully. Look for insects, plant debris and egg masses like spotted lanternfly egg masses, which can blend into outdoor surfaces and look like smears of mud or clumps of dirt. A few minutes of checking and cleaning before you move can help prevent pests from invading your new neighborhood.
Invasive pests cost the U.S. billions of dollars every year and damage forests, farms, parks and backyards. Stopping invasive pests starts with simple steps anyone can take: checking what you pack, clean, move and buy. When everyone does their part, fewer pests spread and communities stay healthier and more resilient.
Visit aphis.usda.gov/hungrypests to learn more about how invasive pests spread and the simple steps you can take to help stop them and protect America’s agriculture and natural resources.
Invasive Pest Protection Checklist
- Declare all food, plants and agricultural items when returning from another country.
- When ordering items online, check where the products ship from and verify U.S. import rules before buying.
- If you’re camping, buy firewood where you plan to burn it. Clean clothing, gear and vehicles before leaving.
- Before moving to a new home, inspect outdoor furniture and equipment, looking closely for egg masses or insects.
Content courtesy of USDA.
SOURCE:
United States Department of Agriculture
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Lifestyle
Get Your Kids Ready to Go Back-to-School with Affordable Health Coverage
Once school starts, life moves fast. There is homework, practices, permission slips, and early mornings. Before the calendar fills up, take a moment to make sure your child has affordable health coverage for the year ahead.
Get Your Kids Ready to Go Back-to-School with Affordable Health Coverage
(Feature Impact) Once school starts, life moves fast. There is homework, practices, permission slips, and early mornings. Before the calendar fills up, take a moment to make sure your child has health coverage for the year ahead.
Free or low-cost health coverage is available through the Children’s Health Insurance Program (CHIP) or Medicaid in your state for eligible individuals. With health coverage, your kids and teens can get the care they need to stay healthy and do well in school.
Think your family might not qualify? You might be surprised. Many families may qualify for coverage without realizing it! Eligibility varies by state and is based on family income and household size. In most states, children up to age 19 from a family of four earning up to $80,000 per year may be eligible. In some states, eligible children can still qualify if family income is even higher.
Getting your child covered helps you get them the health care they may need. When a child is sick, the right medicines help them get back to school. If a child has a tough time focusing, there are supports to help. If your child does not see as well as other children, these programs cover glasses. Healthy kids are confident kids, who are ready to participate in every opportunity inside and outside the classroom!
Why Health Coverage Belongs on Your Kids’ Back-to-School List
Having health coverage can help families, like yours, to send your kids and teens off to school ready to learn. Depending on the program and a child’s individual needs, Medicaid and CHIP can provide eligible kids up to age 18 (Medicaid) or 19 (CHIP) with a range of services to support their health all year long, such as:
- Annual checkups and school physicals to prepare children to learn, play, and participate.
- Preventive care to identify health needs early and keep children healthy throughout the year.
- Dental care to help prevent tooth aches, cavities, and missed school days.
- Vision and hearing services to support learning and classroom participation.
- Mental health care to support emotional well-being and school success.
- Prescription medications and treatment to help manage symptoms and stay on track.
- Specialized services for children with disabilities to support growth and learning.
How to Apply
You can apply for Medicaid and CHIP in many ways:
- By phone
- By mail
- In-person through your state’s Medicaid or CHIP office
- Or find your state’s information online at InsureKidsNow.gov/coverage.
Act now to get your child covered before they need health care. Enrollment for these programs is open year-round, meaning families do not have to wait for a specific time of year to get covered.
Once enrolled, coverage must be renewed every twelve months, so it is important to keep your address, email, and phone number up to date with your state Medicaid or CHIP office to avoid missing important renewal information. Visit InsureKidsNow.gov or call 1-877-KIDS-NOW (1-877-543-7669) for more information.
Information provided by the U.S. Department of Health & Human Services. This communication was printed, published, or produced and disseminated at U.S. taxpayer expense.
Photo courtesy of Shutterstock
SOURCE:
Centers for Medicare and Medicaid Services
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Lifestyle
Strong at Every Age: How Women Can Help Combat Muscle Loss
Combat Muscle Loss: Aging is inevitable, but losing muscle and mobility doesn’t have to be. Consider these tips to help women protect their muscle health.
Strong at Every Age: How Women Can Help Combat Muscle Loss
(Feature Impact) Aging is inevitable, but losing muscle and mobility doesn’t have to be. For many women, maintaining strength, independence, energy and mobility are top priorities as they get older, particularly as they deal with the mental and physical responsibilities that come with working, caregiving, keeping up with friends, hobbies and enjoying an active lifestyle.
In fact, 58% of women in the United States are actively focused on staying healthy as they age, according to a recent survey commissioned by Viactiv, a line of award-winning supplements for women known for their unique formats and flavors. However, 73% of respondents weren’t aware of sarcopenia, or age-related muscle loss. According to the “International Journal of Women’s Health,” age-related muscle loss often begins between ages 30-35, with women losing 3-8% of their muscle mass per decade and increasing to 5-10% loss per decade after age 60.
Hormonal changes, decreased activity levels, stress, poor sleep and inadequate nutrition can all contribute to the decline in muscle, which can also negatively impact balance, bone health, metabolism, posture and everyday mobility.
Yet, despite 70% of women reporting some level of concern about muscle loss, 54% are unsure how to protect their muscle health.
“Women want to stay strong, active and independent as they age, but many are getting mixed messages about what actually supports long-term muscle health,” said Dr. Tania Elliott, a dual board-certified physician in internal medicine. “A lot of women are already making healthy choices like walking and staying active, which is a great start. However, maintaining muscle health really requires a more complete approach, and one that starts earlier than most women think, which is in your 30s.”
Prioritize Strength Training
Many women report barriers such as lack of time (15%), feeling overwhelmed (23%) or simply not enjoying exercise (23%). The key is finding realistic, sustainable habits. While walking and cardio exercise aid in heart health, which 58% of survey respondents report already engaging in, strength training is one of the most effective ways to preserve and build muscle as you age. Still, just 34% of women report doing strength or resistance training.
You don’t need an intense fitness regimen to support healthy aging. Aiming for at least two strength-focused workouts a week – lifting weights, using resistance bands, practicing weight-bearing yoga or doing bodyweight exercises like squats and pushups – that target major muscle groups can help maintain muscle health. The goal is to fatigue your muscles during sets so they build.
Fuel Muscles with Proper Nutrition
Exercise is only part of the equation. Muscles also need proper nutrition to recover and stay strong. Protein plays a critical role in maintaining muscle mass, especially as women age. Incorporating high-quality protein throughout the day, such as eggs, Greek yogurt, fish, lean meats, beans, lentils, nuts and seeds, may help support muscle repair and overall strength.
Support Healthy Aging with Supplements
In addition to a balanced diet and exercise, some women may consider supplements that support healthy aging and energy production, including CoQ10, which is a naturally occurring antioxidant that helps cells produce energy. According to research published in “The Journal of Nutrition, Health and Aging,” because muscles require significant energy to function, CoQ10 shows potential for managing sarcopenia by improving mitochondrial function and reducing oxidative stress.
An option like Viactiv CoQ10 Cardio Complete, available in a tasty fruit-flavored chew, can help support heart health, muscles, nerve function and daily energy. Enhanced with vitamins D3 and K2, it provides daily essential nutrition for women without the need to swallow a large pill.
Practice Healthy Habits
Muscle health is influenced by more than workouts. Sleep, stress management and daily movement all play important roles. Adopting some simple habits, including prioritizing quality sleep, stretching regularly, staying properly hydrated, reducing sedentary time throughout the day and practicing stress-management techniques, like yoga, meditation or deep breathing, can help aid in healthy aging, including maintaining muscle.
The earlier women begin prioritizing muscle health, the better positioned they may be to maintain strength and mobility as they age. Visit Viactiv.com for more information and resources to help combat muscle loss.
Photo courtesy of Shutterstock
SOURCE:
Viactiv
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