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Soldiers in Recovery from Alcohol Use Disorder Who Experience Cardiovascular Withdrawal Symptoms May Benefit from Medication Targeting Brain Stress Response

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Newswise — Prazosin, a medication FDA-approved for hypertension and used off-label for alcohol use disorder, may help prevent drinking relapse in people with cardiovascular or behavioral symptoms of alcohol withdrawal, according to a new study involving active-duty soldiers. Alcohol use disorder (AUD) is highly prevalent among soldiers. Prazosin reduces the noradrenergic signaling that is key to regulating the brain stress response. Overactivity of the noradrenergic system produces irritability, anxiety, “fight or flight” responses, and sleep disturbance. Noradrenergic activity can increase during abstinence from drinking; consequently, it contributes to mood disturbances, insomnia, and other distressing symptoms of alcohol withdrawal and to the “relief cravings” that can lead to relapse. Elevated noradrenergic activity produces elevated blood pressure and heart rate symptomatic of alcohol withdrawal. Previous research has pointed to the potential of prazosin for reducing alcohol use and cravings. For the study in Alcohol: Clinical & Experimental Research, investigators designed a randomized control trial of prazosin among US active-duty soldiers.

Between 2015 and 2018, researchers enrolled 102 soldiers in this placebo-controlled study. The soldiers were undergoing mandated outpatient treatment for hazardous drinking and were expected to achieve abstinence. That program overlapped with the first nine weeks of the study. Participants were interviewed about their alcohol consumption and were randomized to receive prazosin or placebo for 13 weeks. The soldiers kept diaries recording their number of drinks per day, drinking days per week, and heavy drinking days per week. On weeks nine and 13, they completed questionnaires assessing their alcohol cravings, sleep, and depression symptoms. Those who met diagnostic criteria for PTSD (48 soldiers) were assessed for symptom severity. Researchers tracked participants’ blood pressure, heart rate, and suicidal thinking. They used statistical analysis to compare outcomes of treatment versus placebo among the soldiers, also considering cardiovascular symptoms or PTSD.

The soldiers’ alcohol use had declined steeply even before they were randomized. Nevertheless, on average, those taking prazosin experienced a modest but significant reduction in drinks per day compared to those taking placebo. The differences were more striking among specific subgroups. The 15 soldiers with elevated heart rates were at or near zero drinks by week nine and sustained this through the final four weeks of the study (after the outpatient program ended). Those taking the placebo, in contrast, experienced an alcohol rebound during the latter period. The 27 soldiers on prazosin who had raised blood pressure reported a reduced number of drinks and drinking days compared to those on placebo, with the contrast more notable in the final four weeks. Overall, prazosin did not appear to reduce alcohol cravings more than placebo, a finding that may reflect the particular conditions of this study. Still, within the prazosin group, soldiers with PTSD did experience relief from cravings. This is likely a result of the medication’s countering effect on excessive noradrenergic signaling in PTSD. Depression symptoms were marginally lower among the prazosin group than the placebo controls.

Among soldiers with elevated cardiovascular measures, the benefit of prazosin in reducing drinking was notable despite the participants’ low alcohol consumption at the start of the study. The study findings endorse a “personalized medicine” approach for treating people with AUD at high risk of relapse, including those who experience cardiovascular or behavioral symptoms consistent with alcohol withdrawal. Additional research is needed.

Source: Research Society on Alcoholism

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Children can be systematic problem-solvers at younger ages than psychologists had thought – new research

Child psychologists: Celeste Kidd’s research challenges long-standing ideas from Jean Piaget about children’s problem-solving abilities. Her findings show that children as young as four can independently utilize algorithmic strategies to solve complex tasks, contradicting the belief that systematic logical thinking develops only after age seven. This insight highlights the importance of nurturing algorithmic thinking in early education.

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Last Updated on March 16, 2026 by Daily News Staff

Children can be systematic problem-solvers at younger ages than psychologists had thought – new research
How do kids figure out how to sort things by order? Celeste Kidd

Celeste Kidd, University of California, Berkeley

I’m in a coffee shop when a young child dumps out his mother’s bag in search of fruit snacks. The contents spill onto the table, bench and floor. It’s a chaotic – but functional – solution to the problem.

Children have a penchant for unconventional thinking that, at first glance, can look disordered. This kind of apparently chaotic behavior served as the inspiration for developmental psychologist Jean Piaget’s best-known theory: that children construct their knowledge through experience and must pass through four sequential stages, the first two of which lack the ability to use structured logic.

Piaget remains the GOAT of developmental psychology. He fundamentally and forever changed the world’s view of children by showing that kids do not enter the world with the same conceptual building blocks as adults, but must construct them through experience. No one before or since has amassed such a catalog of quirky child behaviors that researchers even today can replicate within individual children.

While Piaget was certainly correct in observing that children engage in a host of unusual behaviors, my lab recently uncovered evidence that upends some long-standing assumptions about the limits of children’s logical capabilities that originated with his work. Our new paper in the journal Nature Human Behaviour describes how young children are capable of finding systematic solutions to complex problems without any instruction. https://www.youtube.com/embed/Qb4TPj1pxzQ?wmode=transparent&start=0 Jean Piaget describes how children of different ages tackle a sorting task, with varying success.

Putting things in order

Throughout the 1960s, Piaget observed that young children rely on clunky trial-and-error methods rather than systematic strategies when attempting to order objects according to some continuous quantitative dimension, like length. For instance, a 4-year-old child asked to organize sticks from shortest to longest will move them around randomly and usually not achieve the desired final order.

Psychologists have interpreted young children’s inefficient behavior in this kind of ordering task – what we call a seriation task – as an indicator that kids can’t use systematic strategies in problem-solving until at least age 7.

Somewhat counterintuitively, my colleagues and I found that increasing the difficulty and cognitive demands of the seriation task actually prompted young children to discover and use algorithmic solutions to solve it.

Piaget’s classic study asked children to put some visible items like wooden sticks in order by height. Huiwen Alex Yang, a psychology Ph.D. candidate who works on computational models of learning in my lab, cranked up the difficulty for our version of the task. With advice from our collaborator Bill Thompson, Yang designed a computer game that required children to use feedback clues to infer the height order of items hidden behind a wall, .

The game asked children to order bunnylike creatures from shortest to tallest by clicking on their sneakers to swap their places. The creatures only changed places if they were in the wrong order; otherwise they stayed put. Because they could only see the bunnies’ shoes and not their heights, children had to rely on logical inference rather than direct observation to solve the task. Yang tested 123 children between the ages of 4 and 10. https://www.youtube.com/embed/GlsbcE6nOxk?wmode=transparent&start=0 Researcher Huiwen Alex Yang tests 8-year-old Miro on the bunny sorting task. The bunnies are hidden behind a wall with only their sneakers visible. Miro’s selections exemplify use of selection sort, a classic efficient sorting algorithm from computer science. Kidd Lab at UC Berkeley.

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Figuring out a strategy

We found that children independently discovered and applied at least two well-known sorting algorithms. These strategies – called selection sort and shaker sort – are typically studied in computer science.

More than half the children we tested demonstrated evidence of structured algorithmic thinking, and at ages as young as 4 years old. While older kids were more likely to use algorithmic strategies, our finding contrasts with Piaget’s belief that children were incapable of this kind of systematic strategizing before 7 years of age. He thought kids needed to reach what he called the concrete operational stage of development first.

Our results suggest that children are actually capable of spontaneous logical strategy discovery much earlier when circumstances require it. In our task, a trial-and-error strategy could not work because the objects to be ordered were not directly observable; children could not rely on perceptual feedback.

Explaining our results requires a more nuanced interpretation of Piaget’s original data. While children may still favor apparently less logical solutions to problems during the first two Piagetian stages, it’s not because they are incapable of doing otherwise if the situation requires it.

A systematic approach to life

Algorithmic thinking is crucial not only in high-level math classes, but also in everyday life. Imagine that you need to bake two dozen cookies, but your go-to recipe yields only one. You could go through all the steps of making the recipe twice, washing the bowl in between, but you’d never do that because you know that would be inefficient. Instead, you’d double the ingredients and perform each step only once. Algorithmic thinking allows you to identify a systematic way of approaching the need for twice as many cookies that improves the efficiency of your baking.

Algorithmic thinking is an important capacity that’s useful to children as they learn to move and operate in the world – and we now know they have access to these abilities far earlier than psychologists had believed.

That children can engage with algorithmic thinking before formal instruction has important implications for STEM – science, technology, engineering and math –education. Caregivers and educators now need to reconsider when and how they give children the opportunity to tackle more abstract problems and concepts. Knowing that children’s minds are ready for structured problems as early as preschool means we can nurture these abilities earlier in support of stronger math and computational skills.

And have some patience next time you encounter children interacting with the world in ways that are perhaps not super convenient. As you pick up your belongings from a café floor, remember that it’s all part of how children construct their knowledge. Those seemingly chaotic kids are on their way to more obviously logical behavior soon.

Celeste Kidd, Professor of Psychology, University of California, Berkeley

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Why the First Year Behind the Wheel is the Most Dangerous: Data Shows Teen Drivers 3 Times More Likely to be in Fatal Crash

Teen drivers are significantly at risk of fatal crashes, with those aged 16-19 being nearly three times more likely to be involved in accidents than older drivers. The first year of driving presents heightened dangers, but with proper preparation, including coaching, technology, and smart insurance, families can mitigate these risks and promote safety.

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Why the First Year Behind the Wheel is the Most Dangerous: Data Shows Teen Drivers 3 Times More Likely to be in Fatal Crash

Why the First Year Behind the Wheel is the Most Dangerous: Data Shows Teen Drivers 3 Times More Likely to be in Fatal Crash

(Feature Impact) The driver’s license photo may be slightly awkward, but the milestone is unforgettable. For families, a newly licensed teen means independence, busy schedules and a new set of responsibilities.

Motor vehicle crashes remain one of the leading causes of death for U.S. teens, according to the Centers for Disease Control and Prevention (CDC). Data from the National Highway Traffic Safety Administration shows drivers ages 16-19 are nearly three times more likely to be involved in a fatal crash than drivers 20 and older, per mile driven.

The statistics are serious, but they’re also manageable.

“With the right preparation, teen driving doesn’t have to feel overwhelming,” said Susan Irace, manager, divisional claims at Mercury Insurance. “Experience is what young drivers are building. Parents can help shorten that learning curve with structure, technology and smart coverage decisions.”

Why the First Year Matters

Federal safety data shows crash risk is highest in a teen’s first year of independent driving. Night driving, teen passengers and distracted driving increase that risk – while seat belts, graduated licensing laws and supervised practice significantly reduce it.

In 2023, more than 2,800 teens ages 13-19 were killed in motor vehicle crashes nationwide, according to the CDC. However, teen crash rates have declined over time thanks to safer vehicles, graduated driver licensing programs and greater awareness of distracted driving.

Ways to Reduce Teen Driving Risk

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The experts at Mercury Insurance encourage families to focus on preparation rather than panic.

1. Coach Early and Often

  • Log supervised driving time in different conditions – highways, rain, nighttime
  • Create a simple written driving agreement outlining expectations
  • Limit teen passengers during the first year
  • Make seatbelts non-negotiable

2. Let Technology Help

  • Choose vehicles with safety features like automatic emergency braking and blind-spot monitoring
  • Use telematics or safe-driving feedback tools to reinforce good habits
  • Activate smartphone “Do Not Disturb While Driving” settings

3. Review Insurance Before the Keys Change Hands

  • Add teens to your insurance policy promptly
  • Revisit liability limits to protect family assets
  • Ask about good student and driver training discounts

“Insurance is about preparation, not fear,” Irace said. “When families combine active coaching with the right coverage, they’re setting their teen up for safer miles ahead.”

Preparation Turns Risks into Confidence

The first solo drive is a milestone, but preparation determines what comes next. By pairing common-sense coaching with today’s vehicle safety technology and thoughtful insurance planning, families can support independence while managing risk responsibly.

For more teen driver safety tips and coverage guidance, visit MercuryInsurance.com/resources.

Photos courtesy of Shutterstock

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Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.

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Lifestyle

Building a Birdhouse: A Step-by-Step DIY Process

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Last Updated on March 13, 2026 by Daily News Staff

Building a Birdhouse: A Step-by-Step DIY Process

(Feature Impact) To add charm to your yard, encourage local wildlife and give you a front-row seat to nature, building a birdhouse is a simple weekend project that checks all of those boxes.

Building a Birdhouse

Seasoned DIYers and first-timers alike can follow this step-by-step guide to create a functional, welcoming birdhouse.

Step 1: Choose the Right Design
Start by deciding what type of birds you’d like to attract. Different birds prefer different house sizes and entrance types. A simple, classic birdhouse design makes the project beginner-friendly and works well for common backyard birds like wrens, chickadees and bluebirds. In general, plan for at least a 1-1 2/2-inch entrance hole, a 5-by-5-inch interior space and 2 inches or more of roof overhang.

Step 2: Gather Materials and Tools
Most DIY birdhouses can be built with basic materials and tools you may already have at home, including untreated cedar or pine wood, screws or nails, wood glue, sandpaper and exterior-safe paint as well as a measuring tape, pencil, saw and drill.

Step 3: Measure and Cut Wood
Measure and cut wood to make the front panel, back panel, two side panels, floor and roof. Then sand all edges for smooth assembly.

Step 4: Drill Holes
Using a hole-saw bit, drill the entrance hole into the front panel. Position it a few inches below the roofline to keep predators out. Next, drill 2-3 small drainage holes in the floor piece to prevent water buildup and help keep the birdhouse dry.

Step 5: Assemble the Birdhouse
Attach the side panels to the back panel using screws or nails. Add the front panel then secure the floor piece, slightly recessed, so rainwater can drain. Attach the roof last, making sure it slopes slightly to allow water to run off.

Step 6: Paint the Exterior
If you plan to paint your birdhouse, stick to neutral, nature-inspired colors. Light browns, soft greens or white help regulate temperature and blend into the environment.

Step 7: Mount Your Birdhouse
Once dry, place your birdhouse in a quiet, sheltered spot away from heavy foot traffic. Mount or hang it 5-10 feet off the ground, facing away from prevailing winds.

Visit eLivingtoday.com for more DIY project inspiration.

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eLivingtoday.com

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.


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