Lifestyle
Women are at a higher risk of dying from heart disease − in part because doctors don’t take major sex and gender differences into account
Heart disease impacts women differently than men due to genetic and gender biases in healthcare. Awareness and improved treatment approaches are essential for better outcomes.
Last Updated on March 12, 2026 by Daily News Staff
Amy Huebschmann, University of Colorado Anschutz Medical Campus and Judith Regensteiner, University of Colorado Anschutz Medical Campus
A simple difference in the genetic code – two X chromosomes versus one X chromosome and one Y chromosome – can lead to major differences in heart disease. It turns out that these genetic differences influence more than just sex organs and sex assigned at birth – they fundamentally alter the way cardiovascular disease develops and presents.
While sex influences the mechanisms behind how cardiovascular disease develops, gender plays a role in how healthcare providers recognize and manage it. Sex refers to biological characteristics such as genetics, hormones, anatomy and physiology, while gender refers to social, psychological, and cultural constructs. Women are more likely to die after a first heart attack or stroke than men. Women are also more likely to have additional or different heart attack symptoms that go beyond chest pain, such as nausea, jaw pain, dizziness and fatigue. It is often difficult to fully disentangle the influences of sex on cardiovascular disease outcomes versus the influences of gender.
While women who haven’t entered menopause have a lower risk of cardiovascular disease than men, their cardiovascular risk accelerates dramatically after menopause. In addition, if a woman has Type 2 diabetes, her risk of heart attack accelerates to be equivalent to that of men, even if the woman with diabetes has not yet gone through menopause. Further data is needed to better understand differences in cardiovascular disease risk among nonbinary and transgender patients.
Despite these differences, one key thing is the same: Heart attack, stroke and other forms of cardiovascular disease are the leading cause of death for all people, regardless of sex or gender.
We are researchers who study women’s health and the way cardiovascular disease develops and presents differently in women and men. Our work has identified a crucial need to update medical guidelines with more sex-specific approaches to diagnosis and treatment in order to improve health outcomes for all.
Gender differences in heart disease
The reasons behind sex and gender differences in cardiovascular disease are not completely known. Nor are the distinct biological effects of sex, such as hormonal and genetic factors, versus gender, such as social, cultural and psychological factors, clearly differentiated.
What researchers do know is that the accumulated evidence of what good heart care should look like for women compared with men has as many holes in it as Swiss cheese. Medical evidence for treating cardiovascular disease often comes from trials that excluded women, since women for the most part weren’t included in scientific research until the NIH Revitalization Act of 1993. For example, current guidelines to treat cardiovascular risk factors such as high blood pressure are based primarily on data from men. This is despite evidence that differences in the way that cardiovascular disease develops leads women to experience cardiovascular disease differently.
In addition to sex differences, implicit gender biases among providers and gendered social norms among patients lead clinicians to underestimate the risk of cardiac events in women compared with men. These biases play a role in why women are more likely than men to die from cardiac events. For example, for patients with symptoms that are borderline for cardiovascular disease, clinicians tend to be more aggressive in ordering artery imaging for men than for women. One study linked this tendency to order less aggressive tests for women partly to a gender bias that men are more open than women to taking risks.
In a study of about 3,000 patients with a recent heart attack, women were less likely than men to think that their heart attack symptoms were due to a heart condition. Additionally, most women do not know that cardiovascular disease is the No. 1 cause of death among women. Overall, women’s misperceptions of their own risk may hold them back from getting a doctor to check out possible symptoms of a heart attack or stroke.
These issues are further exacerbated for women of color. Lack of access to health care and additional challenges drive health disparities among underrepresented racial and ethnic minority populations.
Sex difference in heart disease
Cardiovascular disease physically looks different for women and men, specifically in the plaque buildup on artery walls that contributes to illness.
Women have fewer cholesterol crystals and fewer calcium deposits in their artery plaque than men do. Physiological differences in the smallest blood vessels feeding the heart also play a role in cardiovascular outcomes.
Women are more likely than men to have cardiovascular disease that presents as multiple narrowed arteries that are not fully “clogged,” resulting in chest pain because blood flow can’t ratchet up enough to meet higher oxygen demands with exercise, much like a low-flow showerhead. When chest pain presents in this way, doctors call this condition ischemia and no obstructive coronary arteries. In comparison, men are more likely to have a “clogged” artery in a concentrated area that can be opened up with a stent or with cardiac bypass surgery. Options for multiple narrowed arteries have lagged behind treatment options for typical “clogged” arteries, which puts women at a disadvantage.
In addition, in the early stages of a heart attack, the levels of blood markers that indicate damage to the heart are lower in women than in men. This can lead to more missed diagnoses of coronary artery disease in women compared with men.
The reasons for these differences are not fully clear. Some potential factors include differences in artery plaque composition that make men’s plaque more likely to rupture or burst and women’s plaque more likely to erode. Women also have lower heart mass and smaller arteries than men even after taking body size into consideration.
Reducing sex disparities
Too often, women with symptoms of cardiovascular disease are sent away from doctor’s offices because of gender biases that “women don’t get heart disease.”
Considering how symptoms of cardiovascular disease vary by sex and gender could help doctors better care for all patients.
One way that the rubber is meeting the road is with regard to better approaches to diagnosing heart attacks for women and men. Specifically, when diagnosing heart attacks, using sex-specific cutoffs for blood tests that measure heart damage – called high-sensitivity troponin tests – can improve their accuracy, decreasing missed diagnoses, or false negatives, in women while also decreasing overdiagnoses, or false positives, in men.
Our research laboratory’s leaders, collaborators and other internationally recognized research colleagues – some of whom partner with our Ludeman Family Center for Women’s Health Research on the University of Colorado Anschutz Medical Campus – will continue this important work to close this gap between the sexes in health care. Research in this field is critical to shine a light on ways clinicians can better address sex-specific symptoms and to bring forward more tailored treatments.
The Biden administration’s recent executive order to advance women’s health research is paving the way for research to go beyond just understanding what causes sex differences in cardiovascular disease. Developing and testing right-sized approaches to care for each patient can help achieve better health for all.
Amy Huebschmann, Professor of Medicine, University of Colorado Anschutz Medical Campus and Judith Regensteiner, Professor of Medicine, University of Colorado Anschutz Medical Campus
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
astronomy for hobbyist
I found a new meteor shower, and it comes from an asteroid getting broken down by the Sun
New Meteor Shower
Across the Earth, every night, thousands of automated stargazers are waiting to take pictures of shooting stars. I am one of the scientists who study these meteors.
Most movies and news alerts focus on large asteroids that could destroy the Earth. And your phones notifies you every few months that an object nine washing machines wide is going to just narrowly skim past. However, the small dust and rubble that enter our atmosphere daily tell an equally interesting story.
My planetary science colleagues and I use camera observations of the night sky to better understand dust, car-sized asteroids and debris from comets in our solar system.
In a study published in March 2026, I searched through millions of meteor observations collected by all-sky camera networks based in Canada, Japan, California and Europe and found a small, recently formed cluster. The 282 meteors associated with this cluster tell the story of an asteroid that got a little too close to the Sun.
Meteor formation
When a sand-sized crumb of space rock hits our atmosphere, it heats up almost instantly, vaporizing its surface layer and turning it into an electrically charged gas. The whole fragment starts to glow — this is what we call a meteor. If the object is larger, like a boulder, and brighter, it’s called a bolide or a fireball. On average, these objects hit our atmosphere going over 15 miles per second. For small dust or sand-sized objects, the whole process lasts only a fraction of a second before they completely disappear.
Most of these sand-sized fragments in the solar system originate from comets – cold, icy objects from the outer reaches of the solar system. As comets pass by the Sun, their icy components turn to gas, releasing tons of dust. This is why comets are often called “dirty snowballs” and appear fuzzy in telescopic images.
Asteroids, on the other hand, are leftovers from the early solar system that formed closer to the Sun. They are dry and rocky, and do not have the same ices that give comets their characteristic tails.
What does it mean to be active?
Astronomers call an asteroid or comet “active” when it sheds dust, gas or larger fragments. This activity is caused by some external force on the object in space, like heat from the Sun, a small impact, or when asteroids spin too fast and fly apart.
Understanding and identifying activity helps scientists better understand how these objects change over time.
For comets, sublimation of ices – when solid ice turns directly into gas, skipping the liquid phase – is the primary culprit. However, for asteroids, the reason for activity can vary greatly.
For example, NASA’s OSIRIS-REx mission, which launched into space to study an asteroid named Bennu, saw activity from its surface, with heat stress and small impacts among the leading explanations.
Other sources for asteroid activity include breakup when an asteroid spins too fast, tidal forces ripping apart asteroids during close encounters with a planet, or gas release.
Researchers most commonly search for activity using telescopes. Astronomers can look for a “tail” or fuzziness around the object. This tail is a clear sign that there is gas and dust around the body. But there is another way to search for activity – meteor showers.
Finding hidden asteroids via meteor showers
The most famous active asteroid is 3200 Phaethon. It is the parent body of the Geminid meteor shower that occurs every year in mid-December. During past close approaches with the Sun, Phaethon released vast amounts of dust and larger fragments. These morsels of Phaethon have spread out along its entire orbit over time, leading to the present Geminid meteor stream.
Each meteor shower we observe occurs when the Earth passes through one of these debris streams. So if astronomers can detect meteor showers, they can also be used to find active objects in space.
At first, debris shed by an asteroid or comet travels closely together. Imagine squeezing a single drop of food dye into a moving stream of water: Initially, the dye stays in a tight, concentrated cloud. But as it flows, the water’s swirling currents pull at the dye, causing it to spread out and fade.
In space, the gravitational tugs from passing planets act like those currents. They pull on the individual meteor fragments in slightly different ways, causing the once-tight stream to gradually drift apart until it completely dilutes into the background dust of our solar system.
The discovery of a rock-comet
In a study published in March 2026 in the Astrophysical Journal, I used millions of observations of meteors to search for recent, unknown activity from asteroids near the Earth. I found one clear cluster of 282 meteors that stood out.
What makes this discovery so exciting is that we are essentially witnessing a hidden asteroid being baked to bits. This newly confirmed meteor stream follows an extreme orbit that plunges almost five times closer to the Sun than Earth does.
Based on how these meteors break apart when they hit our atmosphere, we can tell they are moderately fragile, but tougher than stuff from comets. This finding tells us that intense solar heat is literally cracking the asteroid’s surface, baking out trapped gases and causing it to crumble. This is likely a major source of past Phaethon activity and the main reason the meteorites on Earth are so diverse.
The search for the source
Why does finding a hidden, crumbling asteroid matter? Meteor observations act as a uniquely sensitive probe that lets us study objects that are completely invisible to traditional telescopes.
Beyond solving astronomical mysteries, analyzing this debris helps us understand the physical evolution of asteroids and comets in our solar system. More importantly, it reveals hidden populations of near-Earth asteroids, which is vital information for planetary defense.
The new meteor shower’s parent asteroid remains elusive. However, NASA’s NEO Surveyor mission, launching in 2027, offers a promising solution. This space telescope, dedicated to planetary defense and the discovery of dark, hazardous, Sun-approaching asteroids, will be the ideal tool for searching for the shower’s origin.
Patrick M. Shober, Postdoctoral Fellow in Planetary Sciences, NASA
This article is republished from The Conversation under a Creative Commons license. Read the original article.
The science section of our news blog STM Daily News provides readers with captivating and up-to-date information on the latest scientific discoveries, breakthroughs, and innovations across various fields. We offer engaging and accessible content, ensuring that readers with different levels of scientific knowledge can stay informed. Whether it’s exploring advancements in medicine, astronomy, technology, or environmental sciences, our science section strives to shed light on the intriguing world of scientific exploration and its profound impact on our daily lives. From thought-provoking articles to informative interviews with experts in the field, STM Daily News Science offers a harmonious blend of factual reporting, analysis, and exploration, making it a go-to source for science enthusiasts and curious minds alike. https://stmdailynews.com/category/science/
child education
Making the Grade: How High-Impact Tutoring Builds Student Success
Student Success: If your child is struggling in school, it can feel overwhelming to know how to help. One approach many schools are turning to is high-impact tutoring, also known as high-dosage tutoring.
Making the Grade: How High-Impact Tutoring Builds Student Success
(Feature Impact) If your child is struggling in school, it can feel overwhelming to know how to help. Learning gaps can grow quickly, confidence can slip and what should be simple can start to feel frustrating for both students and parents. But families don’t have to solve this alone. Schools and districts play a critical role in providing the right support. One approach many schools are turning to is high-impact tutoring, also known as high-dosage tutoring.
Backed by extensive research, high-impact tutoring has emerged as one of the most effective school-based strategies for accelerating learning. Studies from EdResearch for Recoveryshow students who participate can gain the equivalent of 3-15 additional months of learning in reading and math within a single school year, making it a powerful tool for accelerating learning and closing achievement gaps.
This type of enrichment goes beyond merely homework help and is vastly different than traditional tutoring. Offered during the school day, many schools and districts across the country are starting to offer proven, structured high-impact tutoring programs by partnering with organizations like Catapult Learning, a leader in providing education solutions that generate demonstrable academic achievement and better life outcomes for students.
Consider these benefits of high-impact tutoring:
Small Group, Big Leaps
A number of factors set high-impact tutoring apart from traditional tutoring. To start, high-impact is most effective when it’s delivered during the school day (either on-site, live virtually or hybrid) in small group settings. Secondly, each session occurs up to five times per week and can be 20-45 minutes in duration. This type of small group instruction delivered with frequency and consistency isn’t just a supplement to classroom learning – it creates a pathway toward academic goals that may not have existed before.
Trusted Tutors, Real Progress
For families, finding the right tutor can feel overwhelming. Vetting private tutors, managing schedules and evaluating quality can be a time-consuming, uncertain exercise. School-based high-impact tutoring removes that guesswork. Districts partner with experienced education organizations to provide vetted, highly trained tutors, structured instructional materials and ongoing progress monitoring.
Through partnerships with school districts nationwide, Catapult Learning helps deliver structured, research-based high-impact tutoring programs that are designed to support students in reading and math, aligning with classroom goals to ensure learners of all skills and abilities receive the right support at the right time. Plus, its research-based instructional materials – combined with exemplary tutors and real-time accountability – allow families to benefit from clear insights into their child’s growth through real data and measurable outcomes.
Flexible and Accessible
High-impact tutoring has the added benefit of being flexible, accessible and less taxing on parents. Because it’s designed to be built directly into the school day, there are no extra trips, costs or added scheduling stresses for families. It’s a hassle-free way for students to get the help they need without burdening parents or caregivers.
Proven Results
The urgency for high-impact tutoring has only increased in the years following the pandemic. The widespread instructional disruptions left countless students with unfinished learning and specific skill gaps traditional classroom time can’t always address. High-impact tutoring offers a targeted way to make up for educational losses and promote equity by providing intensive, individualized instruction to the students who need it most.
Research shows high-impact tutoring is now recognized as the most effective school-based strategy for accelerating learning in reading and math for struggling students. Multiple studies confirm that well-designed tutoring programs produce measurable learning gains.
While many school districts face challenges in providing consistent, high-quality academic support due to limited capacity, staffing and resources, programs implemented by Catapult Learning have demonstrated students can achieve up to eight additional months of learning in reading or math within a single school year. In practical terms, this means students can make accelerated progress toward grade-level expectations, strengthen foundational skills and build confidence in the classroom – all within the structure of the regular school day.
As more schools adopt this approach, families can check with their district to learn whether high-impact tutoring is available. To better understand how these programs are delivered in schools, visit catapultlearning.com for additional information.
SOURCE:
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
The Knowledge
Mosquitoes carrying malaria are evolving more quickly than insecticides can kill them – researchers pinpoint how
Jacob A Tennessen, Harvard University
The fight against infectious disease is a race against evolution. Bacteria become resistant to antibiotics. Viruses adapt to spread more quickly. Diseases transmitted by insects present another evolutionary front: Insects themselves can evolve resistance to the poisons that people use to kill them.
In particular, the mosquito-borne disease malaria kills over 600,000 people annually. Since World War II, people have battled malaria with insecticides – chemical weapons intended to kill Anopheles mosquitoes infected with the Plasmodium parasites that cause the disease.
However, mosquitoes are quickly evolving counterstrategies that make these insecticides ineffective, putting millions of people at greater risk of deadly infection. My colleagues and I have newly published research showing how.
Insecticide resistance threatens public health
As an evolutionary geneticist, I study natural selection – the basis for adaptive evolution. Genetic variants that best promote survival can replace less advantageous versions, causing species to change. Anopheles mosquitoes are frustratingly adept at evolving.
In the mid-1990s, most African Anopheles were susceptible to pyrethroids, a popular type of insecticide originally derived from chrysanthemums. Anopheles control relies on two pyrethroid-based methods: insecticide-treated bed nets to protect sleepers, and indoor residual spraying of insecticide against the walls of homes. These two methods alone likely prevented over a half-billion cases of malaria between 2000 and 2015.
However, mosquitoes today from Ghana to Malawi are often able to survive insecticide concentrations 10 times the previously lethal dose. Along with Anopheles control efforts, agriculture also inadvertently exposes mosquitoes to pyrethroids and contributes to insecticide resistance.
In some African locales, Anopheles is already showing resistance to all four main classes of insecticide used for malaria control.
Adaptation in Latin American mosquitoes
Anopheles mosquitoes and the malaria-causing Plasmodium also occur outside Africa, where insecticide resistance is less well-researched.
In much of South America, the main malaria vector is Anopheles darlingi. This mosquito species has diverged evolutionarily from the African vectors so extensively that it might be a different genus, Nyssorhynchus. Along with colleagues from eight countries, I analyzed over 1,000 Anopheles darlingi genomes to understand its genetic diversity, including any recent changes due to human activity. My collaborators collected these mosquitoes at 16 locations ranging from the Atlantic coast of Brazil to the Pacific side of the Andes in Colombia.
We found that, like its African counterparts, Anopheles darlingi shows extremely high genetic diversity – more than 20 times that of humans – indicating that very large populations of this insect exist. A species with such a vast gene pool is well poised to adapt to new challenges. The right mutation giving it the advantage it needs is more likely to pop up when there are so many individuals. And once that mutation starts to spread, it’s protected by numbers since it won’t be wiped out if a few mosquitoes die by chance.
In contrast, bald eagles in the contiguous U.S. were never able to evolve resistance against the insecticide DDT and approached extinction. Evolution is more efficient among millions of insects than mere thousands of birds. And indeed, we saw signals of adaptive evolution in the resistance-related genes of Anopheles darlingi occurring over the past few decades.
Mosquitoes evolve to detoxify poisons
Insecticides like pyrethroids and DDT share the same molecular target: channels in nerve cells that can open and close. When open, the nerve cell stimulates other cells. These insecticides force the channels to remain open and continuously fire, causing paralysis and death. However, insects can evolve resistance by changing the shape of the channel itself.
Earlier genetic scans performed by other researchers had not detected this type of resistance in Anopheles darlingi, and neither did ours. Instead, we found that resistance is evolving in another way: a group of genes encoding enzymes that break down toxic compounds. High activity of these enzymes, called P450, frequently underlies resistance to insecticides in other mosquitoes. The same cluster of P450 genes has changed independently at least seven times across South America since insecticide use began in the mid-20th century.
In French Guiana, a different set of P450 genes exhibits a similar evolutionary pattern, cementing the clear connection between these enzymes and adaptation. Moreover, when we exposed mosquitoes to pyrethroids in sealed bottles, differences among the P450 genes of individual mosquitoes were linked to the length of time they stayed alive.
Insecticide-heavy campaigns against malaria have been only sporadic in South America and may not be the main driver behind this evolution. Instead, it’s possible that mosquitoes are being exposed indirectly to agricultural insecticides. Intriguingly, we saw the strongest signs of evolution in places where farming is prevalent.
Toward more sophisticated vector control
Despite new vaccines and other recent advances against malaria, mosquito control remains essential for reducing disease.
Some countries are launching trials of gene drives to control malaria, which involve forcing a genetic modification into a mosquito population to reduce their numbers or their tolerance for Plasmodium. Such prospects are exciting, though the relentless adaptability of mosquitoes could be an obstacle.
I and others are revising methods to efficiently test for emerging insecticide resistance. Genome-scale sequencing remains important to detect new or unexpected evolutionary responses. The risk of adaptation is highest under a continuous, strong selection pressure, so minimizing, switching and staggering pesticides can help thwart resistance.
Success in the fight against evolving resistance will require a coordinated effort of monitoring, and reacting accordingly. Unlike evolution, humans can think ahead.
Jacob A Tennessen, Research Scientist in Immunology and Infectious Diseases, Harvard University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
The science section of our news blog STM Daily News provides readers with captivating and up-to-date information on the latest scientific discoveries, breakthroughs, and innovations across various fields. We offer engaging and accessible content, ensuring that readers with different levels of scientific knowledge can stay informed. Whether it’s exploring advancements in medicine, astronomy, technology, or environmental sciences, our science section strives to shed light on the intriguing world of scientific exploration and its profound impact on our daily lives. From thought-provoking articles to informative interviews with experts in the field, STM Daily News Science offers a harmonious blend of factual reporting, analysis, and exploration, making it a go-to source for science enthusiasts and curious minds alike. https://stmdailynews.com/category/science/
