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A Milestone in Prostate Cancer Research: The Inspiring Success of the RESPOND Study

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In a monumental stride toward understanding and combating prostate cancer disparities, the RESPOND study has achieved a landmark victory by recruiting the largest cohort of African American men for prostate cancer research. This comes at a time when the need for such studies is more critical than ever, particularly given the disproportionate impact prostate cancer has on African American men.

Chasing Better Outcomes Amidst Challenges

Statistics reveal daunting disparities: African American men suffer from higher rates of prostate cancer with earlier onset and twice the mortality rate compared to other racial groups. Spearheaded by Dr. Christopher Haiman, a genetic epidemiologist at the University of Southern California (USC), the RESPOND study (Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Tumor Markers, and Social Stress) has made remarkable strides in recruiting over 12,600 volunteers, far surpassing its initial goals.

RESPOND
Dr. Christopher Haiman, a genetic epidemiologist at the University of Southern California, is the RESPOND study’s principal investigator.

This success didn’t come easy, especially as the study’s recruitment phase coincided with the dual upheavals of the COVID-19 pandemic and a national reckoning with racial injustice under the Black Lives Matter movement. Nevertheless, the determination and innovative approaches employed by the RESPOND team, including using sophisticated tools like genome-wide genotyping and next-generation sequencing, have not only kept the study on track but also enriched its potential outcomes.

Understanding the Layers: From Genetics to Social Stress

The broad, holistic design of RESPOND allows examination of various factors potentially contributing to the stark disparities seen in prostate cancer outcomes among African American men. Dr. Haiman pointed out the use of geospatial information systems (GIS) to scrutinize the impact of environmental and social stresses on these men. Also, the study is delving into the roles of structural factors such as residential redlining, which historically denied essential services and opportunities based on racial composition of neighborhoods, thus potentially contributing to health disparities.

The Power of Collaboration and Community Engagement

The success of RESPOND owes much to Dr. Ann Hamilton, who co-leads the recruitment efforts drawing from her extensive background in epidemiological studies. Their team’s strategy involved direct engagement with the community, highlighting not only the immediate benefits of participation but also the long-term impacts for future generations. Collaborations with advocacy groups and leveraging community trust were also key to addressing and overcoming the skepticism often associated with participation in medical research among African American communities.

RESPOND
University of Southern California epidemiologist and the RESPOND’s recruitment lead, Dr. Ann Hamilton, with Mr. Freddie Muse, Jr., a men’s health advocate, at a prostate health event in Los Angeles.

The Road Ahead: Data Analysis and Future Research

As RESPond shifts from recruitment to data analysis, the possibilities are promising. Dr. Haiman envisions a series of future studies that could look into treatment types and their effects on survival rates, the use of AI in detecting tumor signatures, and genetic and lifestyle factors contributing to prostate cancer risks among African American men.

Each step forward not only brings us closer to understanding the complex interplay of factors contributing to cancer disparities but also underscores the crucial need for tailored medical research that respects and responds to the unique needs of diverse populations.

A Beacon of Hope

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RESPOND stands as a beacon of hope, not just for those battling prostate and other forms of cancers but for the medical research community at large. It exemplifies how perseverance, innovation, and community engagement can come together to pave the way for groundbreaking advancements in health and medicine.

The thorough engagement of over 12,600 African American men in this significant study not only marks a historic achievement but also sets the stage for profound impacts on public health policies and future research methodologies. Through their dedication, the RESPOND team is creating a legacy that will benefit many generations to come, truly embodying the ethos of doing ‘what is needed for future generations’.

A Moment of Reflection

As we move forward, it is crucial to reflect on the lessons learned from the RESPOND study – lessons about resilience, the power of community, and the imperative to continually bridge gaps in healthcare disparities. The journey of RESPOND is far from over, but its impacts will resonate for years to, shaping the contours of minority health research and policy.

The journey towards equitable health outcomes continues, and thanks to initiatives like RESPOND, we are another step closer to a future where health disparities are no longer a barrier to living long, healthy lives.


RESPOND study

Support & Further Reading
For further details on the RESPOND study and to support this critical research, please visit RESPOND Study Website. Together, we can make a difference in the lives of millions.

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Consumer Corner

Cold cities are the most ready for winter, with one exception. See where your city ranks

Cold cities? Every neighborhood has a mix of homeowners who approach seasonal home maintenance differently – there are the people who stay on schedule, and on the other end, the procrastinators. There are the dedicated DIYers, and those who have their favorite maintenance pro saved as a favorite contact in their phone. As it turns out, cities are no different. Some metropolitan areas keep their neighborhoods in tip-top shape, while others are a little more slow-going.

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Cold cities are the most ready for winter, with one exception. See where your city ranks

Cold cities are the most ready for winter, with one exception. See where your city ranks

(Sheeka Sanahori) Every neighborhood has a mix of homeowners who approach seasonal home maintenance differently – there are the people who stay on schedule, and on the other end, the procrastinators. There are the dedicated DIYers, and those who have their favorite maintenance pro saved as a favorite contact in their phone. As it turns out, cities are no different. Some metropolitan areas keep their neighborhoods in tip-top shape, while others are a little more slow-going. 

New data from home services company Angi, covering fall maintenance activity in August, reveals which U.S. metropolitan areas are the most proactive with fall maintenance. Washington, D.C., tops the ranking with the strongest demand for fall maintenance in the country, followed by Columbus, Ohio, and Milwaukee, Wisconsin. Northern cities dominate the rest of the list.

Cleveland, Ohio, and Albany-Schenectady-Troy, New York, round out the top five. Cold-weather markets dominate the ranking, accounting for eight of the 10 most-prepared metros. Rochester, New York; Charlotte, North Carolina; Chicago; Indianapolis; and Pittsburgh complete the top 10.

Least fall-ready metros

Fewer than 1 in 5 American cities is prepping for fall at an above-average rate. Among the 66 metros that recorded at least 100 fall maintenance service requests during the analysis period, Los Angeles had the lowest level of per-capita activity, followed by Oklahoma City and Riverside, California. California accounts for four of the bottom 10 markets, with Los Angeles, Riverside, San Diego and San Francisco all appearing on the list. These metros historically don’t experience the colder winter climates of the Northeast and Midwest, making fall maintenance less of an imperative.

Grand Rapids, Michigan, stands out as the only clearly cold-weather metro among the 10 least-prepared large metros. The New York City metro, which includes Newark and Jersey City, ranked just outside the 10 least-prepared large metros, coming in at number 11. Other New York state metros, including Syracuse, Rochester and the Albany metro area, were on the most prepared list.

Homeowners are choosing upkeep over upgrades

Sixty-three percent of homeowners who have recently hired a professional completed maintenance work, and 58% completed repairs. Although they may be waiting to do that dream kitchen or bath renovation, they’re focusing for now on the maintenance that keeps their homes in order.

The most common fall maintenance projects focus on outdoor upkeep. Nationally, tree trimming was the most popular, followed by lawn and yard waste cleanup and shrub care.

What homeowners should do now

When tackling a home maintenance list, start at the top of the home by inspecting the roof and gutters. Look for loose or damaged shingles, and make sure gutters are debris-free. It’s also a good idea to ensure downspouts direct water far away from the foundation. Homeowners should inspect these areas from the ground or hire a professional if the work requires climbing or feels unsafe.

Next, check for drafts around the windows and doors. Replacing worn weatherstripping and damaged caulk in the fall can prevent warm air from escaping once the heat comes back on. Homeowners should also inspect their HVAC filters and have the heating system checked before the temperatures drop.

Every home’s maintenance needs will vary, depending on the age and condition of the house and where it’s located. Whether homeowners hire a professional or safely address small issues, making the fixes can prevent larger and more expensive problems later.

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The ranking: Metros from most to least prepared

America’s 10 Most Fall-Prepared Metros
1. Washington, D.C.
2. Columbus, Ohio
3. Milwaukee, Wisconsin
4. Cleveland, Ohio
5. Albany-Schenectady-Troy, New York
6. Rochester, New York
7. Charlotte, North Carolina
8. Chicago, Illinois
9. Indianapolis, Indiana
10. Pittsburgh, Pennsylvania

10 Metros With the Most Opportunity to Get Fall-Ready
1. Los Angeles, California
2. Oklahoma City, Oklahoma
3. Riverside, California
4. Miami, Florida
5. San Diego, California
6. Houston, Texas
7. Grand Rapids, Michigan
8. San Francisco, California
9. Austin, Texas
10. Memphis, Tennessee

Methodology

The rankings are based on fall maintenance activity recorded on Angi during August 2026. Projects included yard cleanup, winterization, roofing and gutters, heating systems, water and drainage, outdoor plumbing, fireplaces and chimneys, pest prevention, and snow and storm preparation. U.S. metropolitan areas were ranked by activity per 100,000 residents using 2020 U.S. Census population data. To qualify for the least-prepared ranking, metros were required to have at least five service requests or jobs during the analysis period. The rankings reflect activity on Angi’s platform and are not a complete measure of all home-maintenance activity within each metro. These rankings reflect activity observed on Angi’s platform and should not be interpreted as a complete measure of all home-maintenance behavior within a metro area.

Photo courtesy of Shutterstock

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SOURCE:
Angi

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Type 2 Diabetes Doesn’t Have to Be Your Future: Medicare Has a Benefit That Can Help

Left unchecked, prediabetes can progress to type 2 diabetes. However, with the right support, prediabetes can often be managed or even reversed. If you have Medicare, you may qualify for a Medicare-covered program that can help you lower your chances of developing type 2 diabetes – at no cost to you.

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Type 2 Diabetes Doesn't Have to Be Your Future: Medicare Has a Benefit That Can Help

(Feature Impact) Nearly 1 in 2 people age 65 and older has prediabetes – a condition where blood sugar (glucose) levels run higher than normal. Left unchecked, prediabetes can progress to type 2 diabetes. However, with the right support, prediabetes can often be managed or even reversed. If you have Medicare, you may qualify for a Medicare-covered program that can help you lower your chances of developing type 2 diabetes – at no cost to you.

The Medicare Diabetes Prevention Program is a covered Medicare benefit that gives you practical tools, personalized support, and proven strategies to make healthy lifestyle changes. Learn how to eat better, exercise more, and build healthy habits that stick while guided by a certified coach who helps you every step of the way.

Research shows the program works. People with prediabetes who complete the program result in weight loss, which ultimately leads to reduced risk of type 2 diabetes onset.

What can you expect?

Prevention does not mean you have to make big changes all at once. This program helps you take small, realistic steps that can add up to lasting results. It includes 16 core sessions where you can learn how to reduce your diabetes risk by making healthier meals, moving more, and building healthy habits.

The core sessions are followed by six months of monthly maintenance sessions to help you keep your momentum.

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You can choose the class format that works for you

You can enroll in these services from approved Medicare Diabetes Prevention Program suppliers and participate in the way most convenient for you:

  • In-Person: Attend sessions in a community location.
  • Live-Distance Learning: Join interactive group sessions from home.
  • Self-Paced Online: This new option allows you to access online content and learn on your own schedule. 

Visit www.medicare.gov/PreventDiabetes to find a class that’s right for you.

Who is eligible?

You may qualify if you are enrolled in Medicare Part B and meet these criteria:

  • Have had one of the following test results within the past 12 months:
    • Hemoglobin A1c between 5.7% and 6.4%
    • Fasting plasma glucose between 110 and 125 mg/dL
    • Two-hour plasma glucose between 140 and 199 mg/dL after an oral glucose tolerance test
  • Have a body mass index (BMI) of 25 or higher (or 23 or higher if you self-report as Asian descent).
  • Have never been diagnosed with type 1 or type 2 diabetes or end-stage renal disease (ESRD).

What does it cost?

If you have Medicare Part B and qualify for the program, you pay nothing to participate. If you are in a Medicare Advantage Plan, you may have to go to an in-network provider to get these services. Contact your plan for more information.

Ready to get started on your healthier future?

Take control of your health on your own terms, schedule, and pace that fits into your life. Check with your doctor to find out if you have prediabetes or are at risk for developing type 2 diabetes. If you’re eligible for the Medicare Diabetes Prevention Program, your doctor can refer you, or you can enroll on your own.

If you’re ready to get started today, find the class that’s right for you at: www.medicare.gov/PreventDiabetes.

Information provided by the U.S. Department of Health and Human Services

Photos courtesy of Shutterstock

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SOURCE:

Centers for Medicare & Medicaid Services

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The Oral and Cardiovascular Health Connection: 4 Tips to Protect Your Teeth, Gums and Heart

People often think of dentists and doctors as totally separate healthcare professionals: one cares for your teeth and mouth while the other handles the rest of the body. In reality, the different systems in the human body are closely interconnected and oral health is no exception, making dentists a vital part of your healthcare team. Care for your teeth, gums and heart all at once using these tips.

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The Oral and Cardiovascular Health Connection: 4 Tips to Protect Your Teeth, Gums and Heart

(Feature Impact) People often think of dentists and doctors as totally separate healthcare professionals: one cares for your teeth and mouth while the other handles the rest of the body. In reality, the different systems in the human body are closely interconnected and oral health is no exception, making dentists a vital part of your healthcare team.

Oral health and heart health have a particularly close connection, with inflammation at the core of it. When your gums are inflamed, the resulting bacteria can make their way from your mouth through your bloodstream, potentially contributing to your blood vessels constricting or becoming blocked. This, in turn, may force your heart to work harder and raise your blood pressure, putting you at risk of heart disease and stroke. More than 46% of adults in the U.S. have high blood pressure, and more than 40% of adults age 30 and older are affected by periodontal (gum) disease.

To help address these issues, the American Heart Association’s Healthy Smiles, Healthy Hearts initiative, in collaboration with Delta Dental of California, is encouraging dental teams to take a total-body perspective with their patients. Simple steps like blood pressure screenings during checkups can give a more complete picture of a person’s overall health. If a member of your dental care team pulls out a blood pressure cuff at your next appointment, it’s a good sign.

“The mouth is a gateway to the body and can often reveal more about your total body health than you may think,” said Daniel Croley, D.M.D., chief dental officer at Delta Dental of California and Affiliates. “Oral health professionals have a powerful opportunity to integrate more into their patients’ collective health care team beyond protecting their patients’ teeth By connecting oral health and heart health, this initiative helps dentists identify risks early and guide patients toward care that can improve and even save lives.” 

Care for your teeth, gums and heart all at once using these tips from experts at the American Heart Association.

Follow a Brushing and Flossing Schedule

18104 B detail embed2Good dental health starts with a daily routine. If you don’t want to sheepishly cringe next time the dentist inquires about yours, brush at least twice a day and floss at least once a day to disrupt plaque-forming bacteria. Dentists recommend using toothpaste with fluoride and brushing your teeth and gums thoroughly yet gently, as applying too much pressure can wear away enamel and cause gum recession.

Eat a Healthy Diet and Limit Sugar

Most kids are used to hearing sugar will rot their teeth – and that’s not just a parental scare tactic to get their little hands out of the candy jar. Sugar feeds harmful bacteria in your mouth, producing acid that can cause cavities and gum disease. For a diet your heart and teeth will both appreciate, prioritize vegetables, lean proteins, complex carbohydrates and healthy fats, while limiting added sugars and refined carbohydrates.

Avoid Smoking and Tobacco Products

The connection between smoking and oral disease is well established: smokers face significantly higher risks of developing periodontal disease, losing teeth or being diagnosed with oral cancer. Cigarettes aren’t the only form of tobacco to worry about, either. Vaping, dipping and chewing tobacco can also harm your dental health by drying out your mouth and restricting blood flow to the gums. Since these products are also harmful to heart health, quitting or avoiding them offers plenty of worthwhile benefits. Seek support if you need help to kick the habit.

Communicate with Your Healthcare Team

Since your body’s systems are connected to each other, it’s helpful to talk to your dentist about your blood pressure and to your doctor about your oral health. Start thinking of your dentist as a key member of your integrated healthcare team. Don’t be afraid to share your medical history, discuss the side effects of any medications you’re taking and ask for personalized recommendations on caring for your teeth, gums and overall health.

To learn more about how to improve your oral and cardiovascular health, visit Heart.org/OralHealth.

Photos courtesy of Shutterstock collect?v=1&tid=UA 482330 7&cid=1955551e 1975 5e52 0cdb 8516071094cd&sc=start&t=pageview&dl=http%3A%2F%2Ftrack.familyfeatures track

SOURCE:

American Heart Association

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