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Popular Nasal Decongestant Falls Short: FDA Advisers Question Efficacy

FDA questions effectiveness of popular nasal decongestant phenylephrine, raising concerns about congestion relief.



In a surprising turn of events, government experts have cast doubt on the effectiveness of the leading decongestant found in popular over-the-counter medications like Sudafed and Dayquil. A recent review conducted by the Food and Drug Administration (FDA) found that the main drug ingredient, phenylephrine, offers no significant relief from nasal congestion. This revelation raises concerns among millions of Americans who rely on these medications for congestion relief.

Phenylephrine became the primary ingredient in over-the-counter decongestants after pseudoephedrine, an older ingredient, was moved behind pharmacy counters due to its potential for illegal drug processing. However, the FDA’s outside advisers unanimously voted against the efficacy of phenylephrine, prompting a reevaluation of its effectiveness. Despite phenylephrine-based versions dominating the market, accounting for four-fifths of the $2.2 billion oral decongestant market, the FDA’s conclusions suggest a need to reconsider their availability.

The FDA review identified significant flaws in the original studies that supported phenylephrine’s approval. These studies, conducted in the 1960s and 1970s, were deemed inadequate by modern standards. Furthermore, three recent, well-conducted studies by reputable pharmaceutical companies found no discernible difference between phenylephrine medications and placebos in relieving congestion. This raises concerns about the effectiveness of phenylephrine, which has relied on outdated research.

The FDA’s advisory panel’s unanimous vote against phenylephrine’s effectiveness could lead to regulatory action requiring drugmakers like Johnson & Johnson and Bayer to withdraw their phenylephrine-based oral decongestants from store shelves. This move may force consumers to opt for behind-the-counter pseudoephedrine products or phenylephrine-based nasal sprays and drops. However, it would necessitate extensive education efforts by the FDA, pharmacists, and drugstores to inform consumers about alternative options for treating congestion.

The Consumer Healthcare Products Association, representing nonprescription drugmakers, argued that the recent studies have limitations and advocated for continued “easy access” to phenylephrine. However, the FDA review highlighted the shortcomings of the original studies and the lack of modern scientific evidence supporting phenylephrine’s efficacy. Balancing public health concerns and consumer access will be a crucial challenge for regulators moving forward.

The FDA’s recent review has cast doubt on the effectiveness of phenylephrine, the key ingredient in popular nasal decongestants. This finding prompts a reevaluation of treatment options for nasal congestion and calls for further research to provide effective relief for individuals in need.

Check out the article from the Associated Press: https://apnews.com/article/sudafed-decongestants-phenylephrine-pseudoephedrine-fda-0f140bafae9a500c5fba05fe764ecb66


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Pickleball in California Sees Unprecedented Growth: Investment Needed

California’s pickleball surge necessitates investment in courts to meet demand and sustain growth.



Pickleball, the popular paddle sport, is experiencing unprecedented growth in California. According to the recently released 2023 State of Pickleball: Participation & Infrastructure Report by Pickleheads and The Sports & Fitness Industry Association (SFIA), the state will need to build a staggering 3,748 courts at a cost of $131.2 million to meet the increasing demand over the next 5-7 years.

The report also reveals that California currently has only 0.67 dedicated pickleball courts per 10,000 people, which is 45% below the national average. In fact, the state ranks 41st in the nation in terms of dedicated court coverage per capita. These figures highlight the urgent need for investment in pickleball infrastructure to keep up with the sport’s meteoric rise.

Brandon Mackie, Co-founder and COO of Pickleheads, emphasizes the significance of this growth, stating, “Pickleball continues to grow at an unprecedented rate in California. Our estimates show the state will need to invest $131M in courts over the next 5-7 years. This represents an exciting challenge for both public and private enterprises in California.”

Pickleheads, the leading online platform for pickleball, has been instrumental in compiling comprehensive data on pickleball courts across the country. Their database currently includes 51,937 courts across 12,081 facilities in the U.S.

To gain further insights into the state of pickleball and its infrastructure, the 2023 State of Pickleball: Participation & Infrastructure Report can be purchased on pickleheads.com for $350.

As pickleball’s popularity continues to soar, the investment and expansion of pickleball facilities in California will play a crucial role in meeting the growing demand and ensuring players have ample opportunities to enjoy the sport.

SOURCE Pickleheads

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Daily News

Dink Ninja Paddle Review: High-Quality Performance!

“Discover the Dink Ninja Paddle’s high-quality performance in our review! Elevate your pickleball game with this top-notch equipment.



“Dink Ninja Paddle Review: Slicing and Dicing Its Way to High-Quality Performance!”

In a recent episode of Sleeves Senior Pickleball Report, renowned host Mike Sliwa took on the challenge of reviewing the Dink Ninja 🥷White Hot Edition 🔥 Carbon Paddle. Known for his expertise and insightful analysis, Mike left no stone unturned as he explored the paddle’s features and performance.

The Dink Ninja paddle boasts an 18k Carbon Fiber face that delivers an impressive combination of power, spin, and accuracy. Its dual layer PP honeycomb core, coupled with a flexible paddle surface, provides an unmatched touch, allowing players to execute precise shots with ease. With a thickness of 16mm, this paddle offers increased power for those aggressive shots on the court.

What sets the Dink Ninja apart is its proprietary textured surface, which effortlessly generates impressive ball spin. Mike Sliwa couldn’t help but be impressed with the paddle’s ability to enhance his game and take it to the next level.

If you’re looking to elevate your pickleball game, the Dink Ninja 🥷White Hot Edition 🔥 Carbon Paddle might just be the game-changer you need. Don’t miss out on this incredible paddle that slices and dices its way to high-quality performance.

Discover everything you need to know about the legendary Dink Ninja paddle by clicking the link below.


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Hyundai 2024 Santa Cruz: Best Urban Pickup by Cars.com

“Hyundai’s 2024 Santa Cruz named Best Urban Pickup by Cars.com, blending adventure with practicality.”



Hyundai’s 2024 Santa Cruz has been named the Best Urban Pickup by Cars.com in their Pickup Truck Buying Guide. The Santa Cruz impressed Cars.com’s editors with its ability to combine adventure and practicality, as well as its range of desirable features. Ricky Lao, the director of product planning at Hyundai Motor America, expressed gratitude for the recognition and emphasized the brand’s commitment to innovative design, powerful drivetrains, driver convenience, and advanced safety features.

The 2023 Hyundai Santa Cruz Night Edition photographed in Irvine, Calif., Aug. 18, 2022.

According to Aaron Bragman, Cars.com’s Detroit Bureau Chief, the Hyundai Santa Cruz is the ideal truck for urban environments. Its sleek and compact design, lockable hard-top tonneau cover, and comfortable ride make it a dream for city dwellers. Additionally, its Surround View Monitor makes parallel parking on narrow city streets a breeze.

To receive a Cars.com Top Pick designation, vehicles must demonstrate solid fuel economy, capability, and value. For pickup trucks, payload and towing capacities are also considered. Moreover, practical attributes that cater to family needs are taken into account, as many pickups are used for this purpose.

Cars.com Inc. is a leading automotive marketplace platform that connects car shoppers with sellers through digital solutions. Hyundai Motor America focuses on “Progress for Humanity” and offers a technology-rich lineup of cars, SUVs, and electrified vehicles to U.S. consumers. In 2022, Hyundai’s dealers sold over 724,000 vehicles in the U.S., with a significant portion produced at Hyundai Motor Manufacturing Alabama. For more information, visit www.HyundaiNews.com.

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Source: Hyundai

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