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Women are at a higher risk of dying from heart disease − in part because doctors don’t take major sex and gender differences into account

Heart disease impacts women differently than men due to genetic and gender biases in healthcare. Awareness and improved treatment approaches are essential for better outcomes.

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Heart disease
Rates of heart disease and cardiac events in women are often underestimated. eternalcreative/iStock via Getty Images

Amy Huebschmann, University of Colorado Anschutz Medical Campus and Judith Regensteiner, University of Colorado Anschutz Medical Campus

A simple difference in the genetic code – two X chromosomes versus one X chromosome and one Y chromosome – can lead to major differences in heart disease. It turns out that these genetic differences influence more than just sex organs and sex assigned at birth – they fundamentally alter the way cardiovascular disease develops and presents.

While sex influences the mechanisms behind how cardiovascular disease develops, gender plays a role in how healthcare providers recognize and manage it. Sex refers to biological characteristics such as genetics, hormones, anatomy and physiology, while gender refers to social, psychological, and cultural constructs. Women are more likely to die after a first heart attack or stroke than men. Women are also more likely to have additional or different heart attack symptoms that go beyond chest pain, such as nausea, jaw pain, dizziness and fatigue. It is often difficult to fully disentangle the influences of sex on cardiovascular disease outcomes versus the influences of gender.

While women who haven’t entered menopause have a lower risk of cardiovascular disease than men, their cardiovascular risk accelerates dramatically after menopause. In addition, if a woman has Type 2 diabetes, her risk of heart attack accelerates to be equivalent to that of men, even if the woman with diabetes has not yet gone through menopause. Further data is needed to better understand differences in cardiovascular disease risk among nonbinary and transgender patients.

Despite these differences, one key thing is the same: Heart attack, stroke and other forms of cardiovascular disease are the leading cause of death for all people, regardless of sex or gender.

We are researchers who study women’s health and the way cardiovascular disease develops and presents differently in women and men. Our work has identified a crucial need to update medical guidelines with more sex-specific approaches to diagnosis and treatment in order to improve health outcomes for all.

Gender differences in heart disease

The reasons behind sex and gender differences in cardiovascular disease are not completely known. Nor are the distinct biological effects of sex, such as hormonal and genetic factors, versus gender, such as social, cultural and psychological factors, clearly differentiated.

What researchers do know is that the accumulated evidence of what good heart care should look like for women compared with men has as many holes in it as Swiss cheese. Medical evidence for treating cardiovascular disease often comes from trials that excluded women, since women for the most part weren’t included in scientific research until the NIH Revitalization Act of 1993. For example, current guidelines to treat cardiovascular risk factors such as high blood pressure are based primarily on data from men. This is despite evidence that differences in the way that cardiovascular disease develops leads women to experience cardiovascular disease differently.

Clinician holding stethoscope against a patient's chest
Gender biases in health care influence the kind of tests and attention that women receive. FG Trade Latin/E+ via Getty Images

In addition to sex differences, implicit gender biases among providers and gendered social norms among patients lead clinicians to underestimate the risk of cardiac events in women compared with men. These biases play a role in why women are more likely than men to die from cardiac events. For example, for patients with symptoms that are borderline for cardiovascular disease, clinicians tend to be more aggressive in ordering artery imaging for men than for women. One study linked this tendency to order less aggressive tests for women partly to a gender bias that men are more open than women to taking risks.

In a study of about 3,000 patients with a recent heart attack, women were less likely than men to think that their heart attack symptoms were due to a heart condition. Additionally, most women do not know that cardiovascular disease is the No. 1 cause of death among women. Overall, women’s misperceptions of their own risk may hold them back from getting a doctor to check out possible symptoms of a heart attack or stroke.

These issues are further exacerbated for women of color. Lack of access to health care and additional challenges drive health disparities among underrepresented racial and ethnic minority populations.

Sex difference in heart disease

Cardiovascular disease physically looks different for women and men, specifically in the plaque buildup on artery walls that contributes to illness.

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Women have fewer cholesterol crystals and fewer calcium deposits in their artery plaque than men do. Physiological differences in the smallest blood vessels feeding the heart also play a role in cardiovascular outcomes.

Women are more likely than men to have cardiovascular disease that presents as multiple narrowed arteries that are not fully “clogged,” resulting in chest pain because blood flow can’t ratchet up enough to meet higher oxygen demands with exercise, much like a low-flow showerhead. When chest pain presents in this way, doctors call this condition ischemia and no obstructive coronary arteries. In comparison, men are more likely to have a “clogged” artery in a concentrated area that can be opened up with a stent or with cardiac bypass surgery. Options for multiple narrowed arteries have lagged behind treatment options for typical “clogged” arteries, which puts women at a disadvantage.

In addition, in the early stages of a heart attack, the levels of blood markers that indicate damage to the heart are lower in women than in men. This can lead to more missed diagnoses of coronary artery disease in women compared with men.

The reasons for these differences are not fully clear. Some potential factors include differences in artery plaque composition that make men’s plaque more likely to rupture or burst and women’s plaque more likely to erode. Women also have lower heart mass and smaller arteries than men even after taking body size into consideration.

Reducing sex disparities

Too often, women with symptoms of cardiovascular disease are sent away from doctor’s offices because of gender biases that “women don’t get heart disease.”

Considering how symptoms of cardiovascular disease vary by sex and gender could help doctors better care for all patients.

One way that the rubber is meeting the road is with regard to better approaches to diagnosing heart attacks for women and men. Specifically, when diagnosing heart attacks, using sex-specific cutoffs for blood tests that measure heart damage – called high-sensitivity troponin tests – can improve their accuracy, decreasing missed diagnoses, or false negatives, in women while also decreasing overdiagnoses, or false positives, in men.

Our research laboratory’s leaders, collaborators and other internationally recognized research colleagues – some of whom partner with our Ludeman Family Center for Women’s Health Research on the University of Colorado Anschutz Medical Campus – will continue this important work to close this gap between the sexes in health care. Research in this field is critical to shine a light on ways clinicians can better address sex-specific symptoms and to bring forward more tailored treatments.

The Biden administration’s recent executive order to advance women’s health research is paving the way for research to go beyond just understanding what causes sex differences in cardiovascular disease. Developing and testing right-sized approaches to care for each patient can help achieve better health for all.

Amy Huebschmann, Professor of Medicine, University of Colorado Anschutz Medical Campus and Judith Regensteiner, Professor of Medicine, University of Colorado Anschutz Medical Campus

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This article is republished from The Conversation under a Creative Commons license. Read the original article.

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.


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Swisse Launches Glam Bites: Zero-Sugar Beauty Gummies Designed for Busy Routines

Swisse launches Glam Bites: delicious beauty gummies with zero sugar, no sugar alcohols, and no artificial flavors, colors, or sweeteners—designed to support beauty from within.

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Swisse’s new Glam Bites feature collagen peptides, hyaluronic acid, biotin, astaxanthin, and more—three targeted formulas for glow, defense, and hair/skin/nails support.*

Swisse Launches Glam Bites: Zero-Sugar Beauty Gummies Designed for Busy Routines

Swisse, the premium supplement brand under Health & Happiness (H&H) Group and a Certified B Corp, is kicking off 2026 with a new way to support “beauty from within.” The company just introduced Swisse Beauty Glam Bites, a line of zero-sugar beauty gummies made with science-backed ingredients—without the usual “junk” found in many gummy supplements. Positioned for today’s always-on lifestyle, Glam Bites aims to make daily self-care feel less like another task and more like a quick, enjoyable habit: bite, nourish, and glow.

What makes Glam Bites different?

Gummy supplements are popular, but they often come with tradeoffs—added sugars, sugar alcohols, artificial flavors, or ingredients that don’t align with cleaner-label preferences. Swisse is leaning into the opposite approach. According to the company, Glam Bites are crafted with:
  • Zero sugar
  • No sugar alcohols
  • No artificial flavors, colors, or sweeteners
  • Gluten-free
  • Free from major allergens (milk, eggs, fish, crustacean shellfish, peanuts, wheat, soybeans, sesame)
That “clean but still tasty” promise is a big part of the launch—especially as more shoppers look for supplements that fit into wellness routines without feeling like a compromise.

A beauty routine that starts from the inside

Swisse is framing Glam Bites as a simple daily add-on that supports skin, hair, and nails through targeted micronutrients. Leading dietitian Dana A. White highlighted the brand’s approach in the announcement, noting that Glam Bites deliver “powerful, science-driven beauty benefits” through a precisely balanced blend of nutrients—while keeping the formula free from artificial colors, flavors, and sweeteners.

The Glam Bites lineup (available now)

Swisse launched Glam Bites in three formulas, each with its own ingredient blend and naturally flavored profile.

1) Hair Skin Nails Glam Bites

  • Price/Count: $19.99 (60 count)
  • Key ingredients: Biotin, Zinc, Bamboo Extract
  • What it supports: Stronger hair and nails, plus skin firmness and elasticity*
  • Flavor: Blood orange (naturally flavored)

2) Glow Skin Glam Bites

  • Price/Count: $24.99 (60 count)
  • Key ingredients: Hyaluronic Acid, Vitamins C & E, Sea Moss, Hydrolyzed Marine Collagen Peptides
  • What it supports: Collagen production, improved elasticity, and a stronger skin barrier*
  • Flavor: Blueberry lavender (naturally flavored)

3) Skin Defense Glam Bites

  • Price/Count: $24.99 (60 count)
  • Key ingredients: Astaxanthin, L-Glutathione, Green Tea Extract
  • What it supports: Healthy aging, even skin tone, and antioxidant protection against environmental stressors*
  • Flavor: Raspberry green tea (naturally flavored)

Why gummies—and why now?

Swisse is launching Glam Bites at a time when gummies are increasingly becoming the preferred supplement format for younger consumers. The company cited research showing:
  • 45% of Gen Z and 31% of millennials favor gummy supplements.
  • 74% of U.S. personal care buyers agree that skin health reflects overall health.
In other words: the market is shifting toward convenience, better taste, and wellness products that connect beauty with whole-body health.

A global wellness brand expanding its portfolio

Swisse was founded in Australia in 1969 and has grown into a global wellness name known for premium supplements made with ingredients backed by scientific research and produced under world-class manufacturing standards. With Glam Bites, the brand is clearly betting on a “cleaner gummy” future—one that fits modern routines and modern label expectations.

Where to buy

Swisse Beauty Glam Bites are available now.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.


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How C-reactive protein outpaced ‘bad’ cholesterol as leading heart disease risk marker

C-reactive protein (CRP) is a key inflammation marker that can predict heart attack and stroke risk—often better than LDL cholesterol. Here’s why it matters.

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C-reactive protein (CRP) is a key inflammation marker that can predict heart attack and stroke risk—often better than LDL cholesterol. Here’s why it matters.
Blood vessel damage from fatty and high-sugar diets leads to inflammation, which can be detected by measuring C-reactive protein. Mohammed Haneefa Nizamudeen/iStock via Getty Images Plus

How C-reactive protein outpaced ‘bad’ cholesterol as leading heart disease risk marker

Mary J. Scourboutakos, Macon & Joan Brock Virginia Health Sciences at Old Dominion University Heart disease is the leading cause of death in the United States. Since researchers first established the link between diet, cholesterol and heart disease in the 1950s, risk for heart disease has been partly assessed based on a patient’s cholesterol levels, which can be routinely measured via blood work at the doctor’s office. However, accumulating evidence over the past two decades demonstrates that a biomarker called C-reactive protein – which signals the presence of low-grade inflammation – is a better predictor of risk for heart disease than cholesterol. As a result, in September 2025, the American College of Cardiology published new recommendations for universal screening of C-reactive protein levels in all patients, alongside measuring cholesterol levels.

What is C-reactive protein?

C-reactive protein is created by the liver in response to infections, tissue damage, chronic inflammatory states from conditions like autoimmune diseases, and metabolic disturbances like obesity and diabetes. Essentially, it is a marker of inflammation – meaning immune system activation – in the body. C-reactive protein can be easily measured with blood work at the doctor’s office. A low C-reactive protein level – under 1 milligram per deciliter – signifies minimal inflammation in the body, which is protective against heart disease. An elevated C-reactive protein level of greater than 3 milligrams per deciliter, signifies increased levels of inflammation and thus increased risk for heart disease. About 52% of Americans have an elevated level of C-reactive protein in their blood. Research shows that C-reactive protein is a better predictive marker for heart attacks and strokes than “bad,” or LDL cholesterol, short for low-density lipoprotein, as well as another commonly measured genetically inherited biomarker called lipoprotein(a). One study found that C-reactive protein can predict heart disease just as well as blood pressure can.

Why does inflammation matter in heart disease?

Inflammation plays a crucial role at every stage in the development and buildup of fatty plaque in the arteries, which causes a condition called atherosclerosis that can lead to heart attacks and strokes. From the moment a blood vessel is damaged, be it from high blood sugar or cigarette smoke, immune cells immediately infiltrate the area. Those immune cells subsequently engulf cholesterol particles that are typically floating around in the blood stream to form a fatty plaque that resides in the wall of the vessel. This process continues for decades until eventually, one day, immune mediators rupture the cap that encloses the plaque. This triggers the formation of a blood clot that obstructs blood flow, starves the surrounding tissues of oxygen and ultimately causes a heart attack or stroke. Hence, cholesterol is only part of the story; it is, in fact, the immune system that facilitates each step in the processes that drive heart disease.
Three-dimensional concept of fatty plaque buildup in an artery.
Fatty plaque buildup in the arteries causes a blockage that starves tissues of oxygen and can lead to a heart attack or stroke. wildpixel/iStock via Getty Images Plus

Can diet influence C-reactive protein levels?

Lifestyle can significantly influence the amount of C-reactive protein produced by the liver. Numerous foods and nutrients have been shown to lower C-reactive protein levels, including dietary fiber from foods like beans, vegetables, nuts and seeds, as well as berries, olive oil, green tea, chia seeds and flaxseeds. Weight loss and exercise can also reduce C-reactive protein levels.
Colorful variety of foods that help lower heart disease risk.
Diet plays a key role in heart disease risk. monticelllo/iStock via Getty Images Plus

Does cholesterol still matter for heart disease risk?

Though cholesterol may not be the most important predictor of risk for heart disease, it does remain highly relevant. However, it’s not just the amount of cholesterol – or more specifically the amount of bad, or LDL, cholesterol – that matters. Two people with the same cholesterol level don’t necessarily have the same risk for heart disease. This is because risk is determined more so by the number of particles that the bad cholesterol is packaged into, as opposed to the total mass of bad cholesterol that’s floating around. More particles means higher risk. That is why a blood test known as apolipoprotein B, which measures the number of cholesterol particles, is a better predictor of risk for heart disease than measurements of total amounts of bad cholesterol. Like cholesterol and C-reactive protein, apolipoprotein B is also influenced by lifestyle factors like exercise, weight loss and diet. Nutrients like fiber, nuts and omega-3 fatty acids are associated with a decreased number of cholesterol particles, while increased sugar intake is associated with a larger number of cholesterol particles. Furthermore, lipoprotein(a), a protein that lives in the wall surrounding cholesterol particles, is another marker that can predict heart disease more accurately than cholesterol levels. This is because the presence of lipoprotein(a) makes cholesterol particles sticky, so to speak, and thus more likely to get trapped in an atherosclerotic plaque. However, unlike other risk factors, lipoprotein(a) levels are purely genetic, thus not influenced by lifestyle, and need only be measured once in a lifetime.

What’s the best way to prevent heart disease?

Ultimately, heart disease is the product of many risk factors and their interactions over a lifetime. Therefore, preventing heart disease is way more complicated than simply eating a cholesterol-free diet, as once thought. Knowing your LDL cholesterol level alongside your C-reactive protein, apolipoprotein B and lipoprotein (a) levels paints a comprehensive picture of risk that can hopefully help motivate long-term commitment to the fundamentals of heart disease prevention. These include eating well, exercising consistently, getting adequate sleep, managing stress productively, maintaining healthy weight and, if applicable, quitting smoking.The Conversation Mary J. Scourboutakos, Adjunct Assistant Professor in Family and Community Medicine, Macon & Joan Brock Virginia Health Sciences at Old Dominion University This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Easy Pet Wellness Routine: 5 Healthy Habits for Dogs and Cats Without the Fuss

Build a simple, effective pet wellness routine with 5 easy habits. Learn how to support your dog or cat’s health through tailored nutrition, functional supplements, exercise, mental enrichment, and stress-reducing environments—without overwhelming your schedule.

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Last Updated on January 9, 2026 by Daily News Staff

Easy Pet Wellness Routine: 5 Healthy Habits for Dogs and Cats Without the Fuss

Easy Pet Wellness Routine: 5 Healthy Habits for Dogs and Cats Without the Fuss

(Family Features) Pets are more than companions – they’re family – and keeping them healthy can be simple, enjoyable and rewarding. Today’s pet parents may be busier than ever, yet they’re also more committed to wellness than previous generations. That means approaching their furry friends’ unique needs with the same balance, care and attention to overall well-being as they do their own. In fact, according to the 2021 Human Animal Bond Research Institute Benchmark Survey of Pet Owners, increased knowledge about the health benefits of the human-animal bond led 91% of pet owners to say they would be more likely to take better care of their pets. Pet health isn’t just about food, however. A holistic approach to wellness combines daily supplements, dental care, exercise, mental enrichment and proactive health, with many owners looking for ways to simplify routines to support their pets every day. These practical ideas can help support a pet’s overall wellness routine. 17690 detail embed2Tailor Flexible Nutrition Plans to Pets’ Needs Every pet is unique, but balanced nutrition forms the foundation of wellness. Dog and cat parents are increasingly seeking customizable food and supplement solutions designed around their furry friend’s age, needs and lifestyle. Age-specific formulations and products featuring natural, minimally processed ingredients and eco-friendly sourcing allow owners to support their pets’ overall health, from mealtime to daily wellness routines. Support Healthy Skin and Coat A pet’s coat often reflects its overall health. Along with a balanced diet and plenty of water, adding a daily supplement can help support a natural shine. While professional grooming keeps dogs and cats looking their best, incorporating regular at-home brushing and bathing with a gentle shampoo strengthens the bond you share and provides an opportunity to spot any changes, like lumps or bumps. Enhance Pet Wellness with Functional Support Even with a balanced diet, many pets may benefit from extra support to maintain their overall well-being. Functional supplements can help target specific needs, including joint mobility, immunity and stress relief. For example, NaturVet’s easy-to-use Lickable supplements – available in Hip & Joint, Calming and Multi-Vitamin formulas for dogs and cats – offer a simple way to make wellness an effortless part of everyday life. Promote Exercise and Mental Enrichment Movement is essential to any wellness routine. Regular walks, agility activities and games help keep pets fit and happy. Physical exercise is only part of the puzzle, though. Interactive toys, puzzle feeders, scent games and agility training help dogs and cats stay mentally sharp, even on days when outdoor activity is limited. Create a Calming Home Environment Dogs and cats can experience stress when routines aren’t followed, just like people. Maintaining a consistent daily schedule and providing a quiet, comfortable space – such as a bed in a low-traffic area – can help promote calm, comfort and security. By taking a few simple, consistent steps each day, pet parents can create a balanced, enjoyable wellness routine that keeps their furry family members healthy, happy and thriving. From functional supplements and daily care habits to exercise, mental enrichment and a calming environment, small efforts can make a big difference, turning everyday care into a rewarding part of life with your pet. To find more practical health and wellness solutions for your pet, visit naturvet.com.   5 Easy Steps to Help Pet Owners Build Healthy Habits Creating a consistent health and wellness routine doesn’t have to be complicated. Consider these simple steps:
  1. Start slow. Introduce new supplements or activities gradually to avoid overwhelming pets.
  2. Be aware. Review product labels and ingredient certifications to ensure they are safe and appropriate for your pet.
  3. Incorporate naturally. Mix functional supplements into meals or use them as a reward for good behavior.
  4. Stay consistent. Small daily actions can add up to long-term health and wellness.
  5. Monitor and adjust. Work with a veterinarian to create a tailored plan and observe your pet’s energy, mobility and mood, adjusting as needed.
collect?v=1&tid=UA 482330 7&cid=1955551e 1975 5e52 0cdb 8516071094cd&sc=start&t=pageview&dl=http%3A%2F%2Ftrack.familyfeatures SOURCE: NaturVet

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.


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