health and wellness
Cannabis Legalization Drives Innovation, Raises Health Concerns
Cannabis legalization is driving innovation, but much of it focuses on commercial products rather than patient health. New research highlights gaps between market growth and medical evidence.
Lucy Xiaolu Wang, UMass Amherst and Nathan W. Chan, UMass Amherst
Cannabis legalization
Innovation in health care saves lives. But not all health innovations have enough evidence to actually benefit patients.
Barriers to innovation are often higher in illicit or restricted markets, including cannabis, stem cells and cryptocurrencies. Researchers face higher costs, limited access to raw materials and data, and stricter regulations.
Cannabis illustrates a particularly confusing tension between regulatory restrictions on one hand and research and innovation on the other.
While the U.S. federal government still classifies cannabis as having “no accepted medical use,” many states have legalized it for medical or recreational use. Meanwhile, the Department of Health and Human Services obtained a cannabis-related patent in 2003 covering potential medical uses of cannabis compounds for protecting the brain from damage or degeneration. The patent was exclusively licensed for commercialization.
Research and innovation on cannabis can take many forms. Clinical trials may study cannabis products as medical treatments, the effects of cannabis on its users, or factors related to abuse and dependence. Meanwhile, cannabis-related patents can be filed for wide-ranging purposes, such as chemical formulations, methods for production or new consumer products like edibles, beverages or vaporizers.
But do these innovations actually benefit consumers and patients?
We are economists studying how institutional changes affect innovation in different markets. Our recently published research found that legalization of recreational cannabis use appears to spur innovation, but primarily in ways that expand commercial opportunities rather than scientific understanding or health benefits for patients.
Cannabis’ evolving legality in the US
Cannabis is a plant that contains chemical compounds called cannabinoids. One such compound, tetrahydrocannabinol, or THC, produces psychoactive effects, while another compound called cannabidiol, or CBD, is often used to relieve anxiety and pain. However, there has been insufficient evidence on how effective cannabis products are in treating medical conditions, as well as a lack of consistent medical and dosing guidance.
At the federal level in the U.S., cannabis has been classified as a Schedule I drug for over a half-century. This classification indicates that the federal government considers cannabis to have a high potential for abuse and no accepted medical use.
As a Schedule I drug, there are significant restrictions on cannabis research. Researchers who seek to conduct cannabis-related clinical trials must obtain approval from both the Food and Drug Administration and the Drug Enforcement Administration, a process that can take over a year. They are also limited to using select varieties of cannabis obtained from federally authorized cannabis suppliers, and are generally prohibited from studying products available in state-authorized markets.
There are ongoing pushes to relax these restrictions. Meanwhile, cannabis has been legalized to varying extents in many states. California became the first state to pass a medical cannabis law in 1996, allowing qualified patients to grow, possess and use cannabis for medical purposes. Many states followed suit in the late 1990s and early 2000s. As of June 2025, 40 states allow medical cannabis use.
A number of states also allow recreational or nonmedical cannabis use among adults, which is regulated in similar ways to alcohol. Colorado and Washington enacted the first recreational cannabis laws in 2012, and there are 24 states that permit adults to use cannabis recreationally as of January 2026.
Altogether, the legal landscape for cannabis in the U.S. has varied considerably across states and over time. States with more permissive laws can lower the costs of medical research and product development with cannabis, even if federal drug scheduling continues to restrict access. For instance, one group of Washington State University researchers asked participants to independently purchase and smoke cannabis from a legal dispensary before returning to their lab for study.
State legalization and cannabis innovation
To systematically examine how state legalization affects cannabis-related innovation, we compiled and analyzed datasets tracking cannabis-related clinical trials and patent applications.
We distinguished different types of cannabis-related innovation. Specifically, we categorized cannabis-related clinical trials based on whether they focused on its potential as a treatment, its usage and effects, or its role in drug abuse. Similarly, we categorized cannabis-related patents based on whether they focused on chemical compounds, medical uses, methods or products.
We also assessed public health concerns across three measures: patents explicitly involving THC; patents with a high risk of misuse; and patents targeting consumers directly, such as high-potency formulations, edibles or vaporizers.
Then, we compared changes in cannabis-related innovation over time in states that legalized cannabis earlier with those in states that did so later or not at all. We measured innovation by counting the number of cannabis-related clinical trials and patent filings. We distinguished between medical and recreational legalization to assess how different policies affect innovation.
Overall, we found that when states legalize cannabis for recreational use, cannabis-related patents increase – but mostly in commercial-oriented areas rather than health-focused ones. Patents were concentrated in market-oriented innovations like cultivation equipment and consumer products, rather than in clinical or science-based research. We also found some evidence that these innovations may raise public health concerns.
Legalization did not result in meaningful increases in clinical trials. This suggests that barriers to cannabis-related clinical research – such as limited access to research-grade cannabis, limited funding and stigma around working with a federally controlled substance – remain substantial.
Gaps between research and product
As 420 – signifying April 20, a day celebrating cannabis culture – approaches each year, public attention turns toward the legal status of cannabis.
The legal landscape has evolved rapidly over the past few decades, and further changes are in the pipeline. Both the Biden and second Trump administrations have made efforts to reclassify cannabis as a Schedule III substance, which would indicate that it has an accepted medical use and low-to-moderate potential for dependence.
These reevaluations of the legality of cannabis come at a critical time. There has been an explosion of recreational cannabis products in recent years, including increasingly potent strains and a wider variety of ways to use cannabis. Meanwhile, critical research on the health and safety of cannabis use has lagged due to heavy restrictions accompanying Schedule I status.
This gap between medical research and product innovation can have significant public health consequences. The 2019 to 2020 outbreak of lung injuries related to e-cigarette or vape use was linked partly to the use of unregulated or illicit cannabis vaping products. These harms highlight the risks of allowing product innovation for controlled substances to outpace scientific understanding.
Policies that significantly reduce obstacles to clinical research can in turn help close the widening gap between cannabis markets and addressing their public health implications.
Lucy Xiaolu Wang, Assistant Professor of Resource Economics, UMass Amherst and Nathan W. Chan, Professor of Resource Economics, UMass Amherst
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Child Health
Pediatric Cancer Goes Beyond a Victory Bell: How Research and Innovation Improve Survivorship Rates
(Feature Impact) For every tear-jerking video found online of a child ringing a bell that signifies a cancer journey victory, there are dozens, if not more, people working behind the scenes. From leading minds in cancer research to doctors, nurses and support staff, a vast network of people and decades of medical advancements make those moments possible.
In fact, in the last 10 years, the FDA approved 10 new immunotherapies and 20 molecularly targeted therapies to treat pediatric cancers, according to the American Association for Cancer Research. Those breakthroughs – and the children they impact – come with a cost, which is why Hyundai Hope on Wheels has served as a pioneer in increasing survival rates by investing $303 million in pediatric cancer research over nearly three decades.
Those funds have supported more than 1,600 grants to 210 institutions, leading to new insights into cancer biology, clinical trials and new drug development while bringing hope at all stages of a child’s cancer journey.
However, there remains work to be accomplished. According to a survey conducted by Atomik Research on behalf of Hyundai Hope on Wheels, 46% of U.S. adults believe that a child ringing a hospital bell after cancer treatment signifies the child is cancer-free and their medical journey is largely over. The reality is more nuanced than that. In fact, more than one-third of respondents said they’re not familiar with the term cancer survivorship or they have heard the term but don’t fully understand what it means.
Many health care organizations define survivorship as beginning at the time of diagnosis and continuing through treatment and beyond. According to the American Association for Cancer Research, children who survive cancer face several long-term physical and psycho-social challenges due to their cancer and treatment, including planned surgeries, additional rounds of radiation or other forms of medical treatment to address common physical challenges stemming from chemotherapy.
Survival rates continue increasing with scientific and technological breakthroughs, up from 75% to 85% in nearly three decades, representing roughly 40,000 more children surviving their diagnoses. More than 3 in 4 U.S. adults are encouraged by that progress.
For survivors, treatment is just the beginning. Research, follow-up care and long-term funding determine what comes next, and every grant funded and every survivorship program backed means more children reaching adulthood.
According to the survey, more than 80% of adults said they’re more likely to support organizations that fund survivorship services, creating opportunities to fund crucial research and support for children facing pediatric cancer. Collaboration among leading minds, made possible by funding from organizations like Hyundai Hope on Wheels, has led to the development of comprehensive approaches to help children thrive during life after cancer, including enhanced medical records, AI integration, socioemotional support and combatting long-term side effects.
Find more information and ways you can join the fight by visiting HyundaiHopeOnWheels.org.
Photo courtesy of Shutterstock
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Child Health
A child rings the cancer bell. Here’s what that moment doesn’t show
Cancer Bell: A child who’s been treated for cancer walks down the hall of a medical facility, nurses and doctors smiling at them from all corners of the room. The child rings a bell, and everyone cheers as the kid hugs their loved ones. These heartfelt videos appear regularly across social media. What helps make each of those moments possible is decades of research and innovation. For every bell-ringing child whose video goes viral online, a longer health journey awaits.
A child rings the cancer bell. Here’s what that moment doesn’t show
(Sheeka Sanahon) A child who’s been treated for cancer walks down the hall of a medical facility, nurses and doctors smiling at them from all corners of the room. The child rings a bell, and everyone cheers as the kid hugs their loved ones. These heartfelt videos appear regularly across social media. What helps make each of those moments possible is decades of research and innovation. In the last 10 years, the Food and Drug Administration (FDA) approved 10 new immunotherapies and 20 molecularly targeted therapies to treat pediatric cancers, according to the American Association for Cancer Research.
For every bell-ringing child whose video goes viral online, a longer health journey awaits. Hyundai Hope on Wheels, which has funded pediatric cancer research for nearly three decades, commissioned a survey to understand how much Americans know about that journey.
As September marks Childhood Cancer Awareness Month, what that journey actually looks like is worth understanding. According to the survey, 46% of U.S. adults believe that a child ringing a hospital bell after cancer treatment signifies the child is cancer-free and their medical journey is largely over. The reality is more nuanced than that.
When cancer survivorship begins
Many health care organizations define survivorship as beginning at the time of diagnosis and continuing through treatment and beyond. Understanding survivorship this way helps recognize that a child’s cancer journey is about more than reaching the end of treatment. It also includes managing long-term physical, emotional and medical needs that may continue for years to come.
More than a third of U.S. adults say they’re not familiar with the term cancer survivorship or they have heard theterm but don’t fully understand what it means.
According to the American Association for Cancer Research, children who survive cancer face several long-term physical and psycho-social challenges due to their cancer and treatment. Children could face planned surgeries, additional rounds of radiation, or other forms of medical treatment to address common physical challenges stemming from chemotherapy. Every child’s medical treatment plan is different based on their specific needs, but one thing is clear: Pediatric cancer survivors need ongoing support as they navigate long-term health challenges.
Supporting children to live long, full lives
More than 3 in 4 U.S. adults are encouraged by the progress in pediatric cancer, up 5 points from last year. There’s good reason to be hopeful, too. According to the American Cancer Society, the survival rate among pediatric cancer patients has increased from 75% to 85% in nearly three decades, representing 40,000 more children surviving their cancer diagnosis.
Survival rates continue to increase thanks to breakthrough science and technology, and higher standards of care. Pediatric cancer research has led to new insights into cancer biology, clinical trials, and new drug development.
More than 8 in 10 adults say they’re more likely to support organizations that fund survivorship services, which creates more opportunities to fund crucial research and support for children facing pediatric cancer.
Methodology
Hyundai Hope on Wheels commissioned Atomik Research to conduct an online survey of 1,005 adults throughout the United States. The margin of error is +/- 3 percentage points with a confidence level of 95%. Fieldwork took place March 19-26, 2026. Atomik Research, part of 4media group, is a creative market research agency.
Photo courtesy of Shutterstock
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Family
The back-to-school haircut is more than hair: Survey finds 94% of parents say their son’s appearance affects their confidence
(Sheeka Sanahon) Parents spend years styling their children, picking out just the right outfits for special occasions, choosing a haircut that suits their sweet little faces, and doing their best to keep up with how quickly they outgrow their shoes. Just as parents begin to master all the moving parts, a new variable gets thrown into the equation: the opinions of the child whose every style decision they once made.
According to survey data from Sport Clips Haircuts, a sports-themed haircutting franchise specializing in haircuts for men and boys, 84% of parents say that by the time their son reaches middle or high school, he cares significantly or somewhat more about his appearance. According to Psychology Today, physical appearance is important for adolescent children as a means to express identity and to fit in with the norms of their peers. What has changed is the amount of pressure on today’s generation of children to present themselves well; 71% of parents surveyed by Sport Clips say boys today face more pressure to look put together going into a new school year than they remember from their own school years.
Preteen and Teen Boys are Developing Their Own Sense of Style
The surveyed parents report that in the coming days and weeks before the new school year begins, more than a third of their preteen and teen boys ask for a back-to-school haircut. Another 22% of parents say both they and their boys bring it up around the same time. That’s more than half of boys already thinking about how they’ll show up on the first day.
If you thought mom and dad’s opinions mattered regarding the type of haircut they want, think again. More than half of boys ages 11 to 17 know exactly what haircut they want to get before the school year begins. Parents report that many of them are inspired by celebrities, athletes or people they follow online.
The Confidence Connection
As children get older and express more desire for choosing their style, giving them the choice to pick what’s right for them can be a great opportunity to boost their confidence. Ninety-five percent of parents say there is a connection between how confident their son feels about his appearance and how he shows up at school, in sports and social activities. Young boys and their parents are thinking about more than just the haircut. Finding clothes that their son feels good in, as well as talking through what he’s most excited and most nervous about for the new school year, are all part of the preparation.
The Back-to-School Checklist
This checklist creates an important set of traditions to get the school year started off on the right foot. While 71% of parents say getting their son a fresh haircut or new hairstyle has become a reliable part of their back-to-school routine, 20% notice their child shift back into school mode when they pick out their first day outfit. For 19%, it’s when he packs or organizes his bag.
The Styles Middle School and High School Boys Are Asking For
So what styles are boys most likely to ask for to start this school year? According to the survey data, 30% of boys want a tapered fade like the haircut U.S. goalkeeper Matt Freese wore during the 2026 World Cup. Nearly a quarter (24%) of respondents said their child wants a classic cut, like the kind of style YouTuber Caylus Cunningham tends to wear. Only 10% of boys are requesting a longer or shaggy style, like actor Jacob Elordi, and even fewer are looking for fringe bangs, the broccoli cut (which is short on the sides and curly on top) or a buzz cut.
A few parents aren’t sure what kind of look their child is going for this school year. Eight percent say they’re not even sure what to call the hairstyle preferred by the boys in their lives.
Methodology: Sport Clips Haircuts commissioned Atomik Research to conduct an online survey of 1,000 adults throughout the United States. The sample consists of U.S. parents of boys aged 11 to 17. The margin of error is +/- 3 percentage points with a confidence level of 95 percent. Fieldwork took place between July 9 and July 15, 2026. Atomik Research, part of 4media group, is a creative market research agency.
Photo courtesy of Shutterstock (children on school bus)
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