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How C-reactive protein outpaced ‘bad’ cholesterol as leading heart disease risk marker
C-reactive protein (CRP) is a key inflammation marker that can predict heart attack and stroke risk—often better than LDL cholesterol. Here’s why it matters.
C-reactive protein is created by the liver in response to infections, tissue damage, chronic inflammatory states from conditions like autoimmune diseases, and metabolic disturbances like obesity and diabetes. Essentially, it is a marker of inflammation – meaning immune system activation – in the body. C-reactive protein can be easily measured with blood work at the doctor’s office. A low C-reactive protein level – under 1 milligram per deciliter – signifies minimal inflammation in the body, which is protective against heart disease. An elevated C-reactive protein level of greater than 3 milligrams per deciliter, signifies increased levels of inflammation and thus increased risk for heart disease. About 52% of Americans have an elevated level of C-reactive protein in their blood. Research shows that C-reactive protein is a better predictive marker for heart attacks and strokes than “bad,” or LDL cholesterol, short for low-density lipoprotein, as well as another commonly measured genetically inherited biomarker called lipoprotein(a). One study found that C-reactive protein can predict heart disease just as well as blood pressure can.
Why does inflammation matter in heart disease?
Inflammation plays a crucial role at every stage in the development and buildup of fatty plaque in the arteries, which causes a condition called atherosclerosis that can lead to heart attacks and strokes. From the moment a blood vessel is damaged, be it from high blood sugar or cigarette smoke, immune cells immediately infiltrate the area. Those immune cells subsequently engulf cholesterol particles that are typically floating around in the blood stream to form a fatty plaque that resides in the wall of the vessel. This process continues for decades until eventually, one day, immune mediators rupture the cap that encloses the plaque. This triggers the formation of a blood clot that obstructs blood flow, starves the surrounding tissues of oxygen and ultimately causes a heart attack or stroke. Hence, cholesterol is only part of the story; it is, in fact, the immune system that facilitates each step in the processes that drive heart disease.Fatty plaque buildup in the arteries causes a blockage that starves tissues of oxygen and can lead to a heart attack or stroke.wildpixel/iStock via Getty Images Plus
Does cholesterol still matter for heart disease risk?
Though cholesterol may not be the most important predictor of risk for heart disease, it does remain highly relevant. However, it’s not just the amount of cholesterol – or more specifically the amount of bad, or LDL, cholesterol – that matters. Two people with the same cholesterol level don’t necessarily have the same risk for heart disease. This is because risk is determined more so by the number of particles that the bad cholesterol is packaged into, as opposed to the total mass of bad cholesterol that’s floating around. More particles means higher risk. That is why a blood test known as apolipoprotein B, which measures the number of cholesterol particles, is a better predictor of risk for heart disease than measurements of total amounts of bad cholesterol. Like cholesterol and C-reactive protein, apolipoprotein B is also influenced by lifestyle factors like exercise, weight loss and diet. Nutrients like fiber, nuts and omega-3 fatty acids are associated with a decreased number of cholesterol particles, while increased sugar intake is associated with a larger number of cholesterol particles. Furthermore, lipoprotein(a), a protein that lives in the wall surrounding cholesterol particles, is another marker that can predict heart disease more accurately than cholesterol levels. This is because the presence of lipoprotein(a) makes cholesterol particles sticky, so to speak, and thus more likely to get trapped in an atherosclerotic plaque. However, unlike other risk factors, lipoprotein(a) levels are purely genetic, thus not influenced by lifestyle, and need only be measured once in a lifetime.
What’s the best way to prevent heart disease?
Ultimately, heart disease is the product of many risk factors and their interactions over a lifetime. Therefore, preventing heart disease is way more complicated than simply eating a cholesterol-free diet, as once thought. Knowing your LDL cholesterol level alongside your C-reactive protein, apolipoprotein B and lipoprotein (a) levels paints a comprehensive picture of risk that can hopefully help motivate long-term commitment to the fundamentals of heart disease prevention. These include eating well, exercising consistently, getting adequate sleep, managing stress productively, maintaining healthy weight and, if applicable, quitting smoking.Mary J. Scourboutakos, Adjunct Assistant Professor in Family and Community Medicine, Macon & Joan Brock Virginia Health Sciences at Old Dominion University This article is republished from The Conversation under a Creative Commons license. Read the original article.
Finding Your Rhythm Again: Reestablishing Routines in the New Year
Routines in the New Year: After weeks of excitement, travel and inconsistent schedules, the transition back to structure can feel daunting. However, with a thoughtful approach, parents can help their children ease back into their daily rhythms, and in the process, restore calm for the entire family.
Finding Your Rhythm Again: Reestablishing Routines in the New Year
(Family Features) The holiday season is special, fun and often a bit chaotic, filled with family gatherings and joyful celebrations. Once the decorations come down and chaos subsides in the new year, many families face a familiar challenge: getting children back into their regular routines. After weeks of excitement, travel and inconsistent schedules, the transition back to structure can feel daunting. However, with a thoughtful approach, parents can help their children ease back into their daily rhythms, and in the process, restore calm for the entire family. Dr. Lauren Loquasto, senior vice president and chief academic officer at The Goddard School, provides this insight and guidance for parents. Understand Why Routines Matter Children thrive on predictability. Routines provide a sense of security, reduce stress and support emotional regulation. Children feel safe, even proud, when they know what comes next. Routines also help them develop independence and self-control. After the holidays, reestablishing these patterns is essential for a smooth return to school and everyday life. Start with Sleep For young children, sleep is the foundation of a successful routine. Consistent sleep supports focus, tolerance and cooperation. For optimal brain repair and growth, preschoolers typically need 10-13 hours of sleep per night, but seasonal festivities can disrupt sleep schedules, frequently leaving children overly tired. Begin by gradually adjusting bedtime by moving it earlier in 15-minute increments each night until you resume your regular schedule. Pair this with calming pre-bedtime rituals like reading or quiet play to signal it’s time to wind down. The morning routine is equally important. Strive for consistent wake-up times, even on the weekends. If your child is resistant, teach them how their sleep routine helps their body and mind. For example: “Your body relaxes and grows stronger when you get enough sleep, so you feel good afterward.” Reintroduce Standard Mealtimes Holiday snacking and large meals at family gatherings can disrupt normal eating habits. Reinstate regular meal and snack times to help your child feel grounded. Offer balanced options and involve them in planning or preparing meals, as they’re more likely to embrace healthy choices when they have a role in the process. Prioritize Physical Activity After extended periods of lounging indoors – and likely an overdose of screen time – children need movement to burn energy and boost their moods. Coordinate outdoor play and family walks. If the weather isn’t cooperative, move around indoors with hide-and-seek and dance sessions. Physical activity not only supports health but also helps regulate sleep and behavior. Strategically Provide Choices When children have a voice, they are more likely to stay engaged and stick to their routines. As your child settles back into familiar patterns, this is an ideal moment to assess where you can ease your grip just enough to support their growing autonomy. This doesn’t mean relinquishing full decision-making power; rather, it’s about offering structured, intentional choices that help them feel a sense of control over their day. You know your child best, so you can determine when to be flexible. For example, it may not matter if they change into their pajamas right after dinner or just before bed but shifting when they go to the bathroom could completely disrupt their routine and, in turn, your day. Model Behavior Children learn by example and they are always watching their parents. If you reestablish and consistently maintain your own routines – healthy meals, quality sleep and physical activity among them – your child is more likely to follow suit. Make it a family effort rather than a set of rules imposed on them, and make it fun. To help routines stick, consider sticker charts to track progress and incentivize independence and accountability. Resetting routines isn’t about perfection; it’s about creating a supportive environment where children feel secure and prepared for what’s ahead. With patience, consistency and a positive attitude, you can help your child start the new year on the right foot. For more parenting guidance and insights, including a blog and webinar series, visit the Parent Resource Center at GoddardSchool.com. Photos courtesy of Shutterstock SOURCE:
Loving-kindness, the feeling cultivated in metta meditation, is very different from romantic love. Anna Sunderland Engels
What loving-kindness meditation is and how to practice it in the new year
Jeremy David Engels, Penn State A popular New Year’s resolution is to take up meditation – specifically mindfulness meditation. This is a healthy choice. Regular mindfulness practice has been linked to many positive health benefits, including reduced stress and anxiety, better sleep and quicker healing after injury and illness. Mindfulness can help us to be present in a distracted world and to feel more at home in our bodies, and in our lives. There are many different types of meditation. Some mindfulness practices ask meditators simply to sit with whatever thoughts, sensations or emotions arise without immediately reacting to them. Such meditations cultivate focus, while granting more freedom in how we respond to whatever events life throws at us. Other meditations ask practitioners to deliberately focus on one emotion – for example, gratitude or love – to deepen the experience of that emotion. The purpose behind this type of meditation is to bring more gratitude, or more love, into one’s life. The more people meditate on love, the easier it is to experience this emotion even when not meditating. One such meditation is known as “metta,” or loving-kindness. As a scholar of communication and mindfulness, as well as a longtime meditation teacher, I have both studied and practiced metta. Here is what loving-kindness means and how to try it out for yourself:
Unbounded, universal love
Loving-kindness, or metta, is the type of love which is practiced by Buddhists around the world. Like many forms of meditation today, there are both secular and religious forms of the practice. One does not need to be a Buddhist to practice loving-kindness. It is for anyone and everyone who wants to live more lovingly. Loving-kindness, the feeling cultivated in metta meditation, is very different from romantic love. In the ancient Pali language, the word “metta” has two root meanings: The first is “gentle,” in the sense of a gentle spring rain that falls on young plants, nourishing them without discrimination. The second is “friend.” Metta is limitless and unbounded love; it is gentle presence and universal friendliness. Metta practice is meant to grow people’s ability to be present for themselves and others without fail.A guided loving-kindness meditation practice. Metta is not reciprocal or conditional. It does not discriminate between us and them, rich and poor, educated and uneducated, popular or unpopular, worthy and unworthy. To practice metta is to give what I describe in my research as “the rarest and most precious gift” – a gift of love offered without any expectation of it being returned.
How to practice loving-kindness meditation
In the fifth century, a Sri Lankan monk, Buddhaghosa, composed an influential meditation text called the “Visuddhimagga,” or “The Path of Purification.” In this text, Buddhaghosa provides instructions for how to practice loving-kindness meditation. Contemporary teachers tend to adapt and modify his instructions. The practice of loving-kindness often involves quietly reciting to oneself several traditional phrases designed to evoke metta, and visualizing the beings who will receive that loving-kindness. Traditionally, the practice begins by sending loving kindness to ourselves. It is typical during this meditation to say:
May I be filled by loving-kindness
May I be safe from inner and outer dangers
May I be well in body and mind
May I be at ease and happy
After speaking these phrases, and feeling the emotions they evoke, next it’s common to direct loving-kindness toward someone – or something – else: It can be a beloved person, a dear friend, a pet, an animal, a favorite tree. The phrases become:
May you be filled by loving-kindness
May you be safe from inner and outer dangers
May you be well in body and mind
May you be at ease and happy
Next, this loving-kindness is directed to a wider circle of friends and loved ones: “May they …” The final step is to gradually expand the circle of well wishes: including the people in our community and town, people everywhere, animals and all living beings, and the whole Earth. This last round of recitation begins: “May we …” In this way, loving-kindness meditation practice opens the heart further and further into life, beginning with the meditator themselves.
Loving-kindness and mindful democracy
Clinical research shows that loving-kindness meditation has a positive effect on mental health, including lessening anxiety and depression, increasing life satisfaction and improving self-acceptance while reducing self-criticism. There is also evidence that loving-kindness meditation increases a sense of connection with other people. The benefits of loving-kindness meditation are not just for the individual. In my research, I show that there are also tremendous benefits for society as a whole. Indeed, the practice of democracy requires us to work together with friends, strangers and even purported “opponents.” This is difficult to do if our hearts are full of hatred and resentment. Each time meditators open their hearts in metta meditation, they prepare themselves to live more loving lives: for their own selves, and for all living beings. Jeremy David Engels, Liberal Arts Endowed Professor of Communication, Penn State This article is republished from The Conversation under a Creative Commons license. Read the original article.
Mary J. Scourboutakos, Adjunct Assistant Professor in Family and Community Medicine, Macon & Joan Brock Virginia Health Sciences at Old Dominion University This article is republished from The Conversation under a Creative Commons license. Read the original article.
Start with Sleep For young children, sleep is the foundation of a successful routine. Consistent sleep supports focus, tolerance and cooperation. For optimal brain repair and growth, preschoolers typically need 10-13 hours of sleep per night, but seasonal festivities can disrupt sleep schedules, frequently leaving children overly tired. Begin by gradually adjusting bedtime by moving it earlier in 15-minute increments each night until you resume your regular schedule. Pair this with calming pre-bedtime rituals like reading or quiet play to signal it’s time to wind down. The morning routine is equally important. Strive for consistent wake-up times, even on the weekends. If your child is resistant, teach them how their sleep routine helps their body and mind. For example: “Your body relaxes and grows stronger when you get enough sleep, so you feel good afterward.” Reintroduce Standard Mealtimes Holiday snacking and large meals at family gatherings can disrupt normal eating habits. Reinstate regular meal and snack times to help your child feel grounded. Offer balanced options and involve them in planning or preparing meals, as they’re more likely to embrace healthy choices when they have a role in the process. Prioritize Physical Activity After extended periods of lounging indoors – and likely an overdose of screen time – children need movement to burn energy and boost their moods. Coordinate outdoor play and family walks. If the weather isn’t cooperative, move around indoors with hide-and-seek and dance sessions. Physical activity not only supports health but also helps regulate sleep and behavior. Strategically Provide Choices When children have a voice, they are more likely to stay engaged and stick to their routines. As your child settles back into familiar patterns, this is an ideal moment to assess where you can ease your grip just enough to support their growing autonomy. This doesn’t mean relinquishing full decision-making power; rather, it’s about offering structured, intentional choices that help them feel a sense of control over their day. You know your child best, so you can determine when to be flexible. For example, it may not matter if they change into their pajamas right after dinner or just before bed but shifting when they go to the bathroom could completely disrupt their routine and, in turn, your day. Model Behavior Children learn by example and they are always watching their parents. If you reestablish and consistently maintain your own routines – healthy meals, quality sleep and physical activity among them – your child is more likely to follow suit. Make it a family effort rather than a set of rules imposed on them, and make it fun. To help routines stick, consider sticker charts to track progress and incentivize independence and accountability. Resetting routines isn’t about perfection; it’s about creating a supportive environment where children feel secure and prepared for what’s ahead. With patience, consistency and a positive attitude, you can help your child start the new year on the right foot. For more parenting guidance and insights, including a blog and webinar series, visit the 
