Breaking News
FDA Moves Forward with Mail-back Envelopes for Opioid Analgesics Dispensed in Outpatient Settings
Agency Continues to Take Steps to Reduce New Cases of Opioid Use Disorder
Agency Continues to Take Steps to Reduce New Cases of Opioid Use Disorder
Today, the U.S. Food and Drug Administration announced it is requiring manufacturers of opioid analgesics dispensed in outpatient settings to make prepaid mail-back envelopes available to outpatient pharmacies and other dispensers as an additional opioid analgesic disposal option for patients.
“Expanding impactful opioid disposal options, such as mail-back envelopes and in-home disposal, for patients to safely and securely dispose of their unused opioid medications is part of the agency’s comprehensive approach to addressing the overdose crisis,” said FDA Commissioner Robert M. Califf, M.D. “We believe these efforts will not only increase convenient disposal options for many Americans, but also reduce unfortunate opportunities for nonmedical use, accidental exposure, overdose and potential new cases of opioid use disorder. We’re pleased to take this first critical step to increase mail-back envelope options in partnership with the U.S. Postal Service.”
The FDA issued notice today to all manufacturers of opioid analgesics used in outpatient settings that they are required to submit the proposed modification to the Opioid Analgesic Risk Evaluation and Mitigation Strategy (OA REMS) within 180 days of the date of the notification letter. The agency anticipates approval of the modified REMS in 2024. When implemented, outpatient pharmacies and other dispensers will have the option to order prepaid mail-back envelopes from opioid analgesic manufacturers, which they may then provide to patients prescribed opioid analgesics. The REMS modification also requires manufacturers to develop educational materials for patients on safe disposal of opioid analgesics, which outpatient pharmacies and other dispensers may also provide to patients.
This action follows a Federal Register notice issued in April 2022 that sought public comment on a potential modification of the OA REMS to require that mail-back envelopes be dispensed and education on safe disposal be provided with opioid analgesics dispensed in an outpatient setting.
Patients commonly report having unused opioid analgesics following surgical procedures and many Americans gain access to opioids through friends or relatives who have unused opioids. Data show educating patients about disposal options may increase the disposal rate of unused opioids and that providing a disposal option along with education could further increase that rate.
Currently, there are multiple mail-back envelope programs operating in the U.S. and mail-back envelopes are commercially available from multiple entities. There are long-standing regulations and policies, under the Drug Enforcement Administration and United States Postal Service, in place to ensure that mail-back envelopes are nondescript, fit for purpose, and can safely and securely transport unused medicines from the patient’s home to the location where they will be destroyed.
“The U.S. Postal Service is proud to partner with the FDA to expand the use of mail-back envelopes as a safe and secure disposal option for prescription opioid analgesics,” said Postal Service Chief Customer and Marketing Officer and Executive Vice President Steven Monteith. “Serving nearly 165 million addresses each day, with more than 31,000 retail locations across the country, the Postal Service makes it convenient for Americans to dispose of unused prescription drugs to help prevent accidental exposure and overdose.”
The FDA continues to consider additional ways to increase safe disposal of unused opioid analgesics. Specifically, the agency is exploring whether manufacturers of opioid analgesic should also be required to make in-home disposal products available to patients who are prescribed opioid analgesics. In an effort to further evaluate this potential option, the agency will participate in the workshop, Defining and Evaluating In-Home Drug Disposal Systems for Opioid AnalgesicsExternal Link Disclaimer, to examine current in-home disposal options hosted by the National Academies of Sciences, Engineering and Medicine’s (NASEM’s) Forum on Drug Discovery, Development, and Translation in June 2023. The FDA has also issued a Federal Register Notice to seek information and comments from the public to aid the agency’s assessment of in-home disposal methods.
These collective efforts are part of the agency’s implementation of the FDA Overdose Prevention Framework that aims to prevent drug overdoses and reduce deaths through impactful and creative actions. The FDA remains focused on responding to all facets of substance use, misuse, substance use disorders, overdose and death in the U.S. through the four priorities of the framework, including; supporting primary prevention by eliminating unnecessary initial prescription drug exposure and inappropriate prolonged prescribing; encouraging harm reduction through innovation and education; advancing development of evidence-based treatments for substance use disorders; and protecting the public from unapproved, diverted or counterfeit drugs presenting overdose risks.
Related Information
- FDA Overdose Prevention Framework
- Information About Naloxone
- Timeline of Selected FDA Activities and Significant Events Addressing Opioid Misuse and Abuse
Source: FDA
News Brief
Earthquake Swarm Shakes Southern California Near Salton Sea
Earthquake Swarm: A swarm of earthquakes near California’s Salton Sea and Brawley area has prompted increased monitoring by seismologists as hundreds of tremors shake the region.
A swarm of earthquakes has been rattling Southern California near the Salton Sea, drawing attention from residents and seismologists across the region.
Salton Sea earthquake swarm?
The activity is centered near Brawley in Imperial County, an area known for frequent seismic movement due to its location within the Brawley Seismic Zone. According to the U.S. Geological Survey, hundreds of small earthquakes have been recorded over the past several days, with the strongest reaching a magnitude of approximately 4.7.
Residents throughout Imperial Valley, parts of Riverside County, and even portions of Arizona reported feeling shaking from several of the larger quakes. Minor incidents such as falling objects and brief power disruptions were also reported, though no major injuries or widespread structural damage have been confirmed at this time.
The region sits near the southern end of the San Andreas Fault and is considered one of California’s most geologically active areas. Scientists say earthquake swarms are relatively common near the Salton Sea because of the interaction between tectonic fault systems and geothermal activity beneath the surface.
While experts continue to monitor the situation closely, they emphasize that earthquake swarms do not necessarily indicate that a larger earthquake is imminent. However, officials encourage residents to review emergency preparedness plans, secure heavy furniture, and keep emergency supplies ready.
The Salton Sea region has experienced similar seismic swarms in the past, making it an important area of study for earthquake researchers and emergency management agencies.
For continued updates on this developing story and other regional news, visit STM Daily News.
Related External Links
- U.S. Geological Survey (USGS) – Earthquake Monitoring
- California Institute of Technology (Caltech)
- California Earthquake Preparedness Guide
- Ready.gov – Earthquake Safety Tips
- USGS – Salton Trough and Seismic Activity
Stay informed with the latest breaking news, trending stories, and real-time updates from around the world on STM Daily News. Visit our Stories This Moment page for continuously updated coverage on major events, technology, transportation, science, entertainment, and more.
Last Updated on May 6, 2026 by Daily News Staff
Second Nature Brands has issued a voluntary recall for certain 10-ounce pouches of SECOND NATURE KETO CRUNCH SMART MIX™ after discovering the product may contain undeclared cashews, pistachios, and cherries. For anyone with allergies or severe sensitivities—especially to tree nuts like cashews and pistachios—this is a serious safety issue.
The company says the affected product was distributed nationwide, both in retail stores and through online orders.
Why this matters
Undeclared allergens are one of the most urgent types of food safety alerts because consumers rely on labels to avoid ingredients that can trigger reactions. Second Nature Brands warns that people with allergies or severe sensitivity to cashews, pistachios, other tree nuts, or cherries could face serious or life-threatening allergic reactions if they consume the recalled product.
As of the announcement, no illnesses have been reported.
How to identify the recalled product
Check your pantry (and any recent online snack orders) for the following details:
- Product: SECOND NATURE KETO CRUNCH SMART MIX™
- Size: 10-ounce pouch
- UPC: 077034013405
- Best if used by date: 2/12/2027 (printed on the backside of the pouch)
Only pouches with the “Best if used by 2/12/2027” date are included. Other Best if used by dates are not affected, according to the company.
What happened
Second Nature Brands says the recall began after it was discovered that product containing cashews, pistachios, and cherries was placed into packaging that did not disclose those allergens. The company reports that a follow-up investigation indicates the issue was caused by a temporary breakdown in production and packaging processes.
The recall is being conducted with the knowledge of the U.S. Food and Drug Administration (FDA).
What consumers should do right now
If you have the affected product:
- Do not consume it.
- Keep the pouch (and take a photo of the UPC and Best if used by date if helpful).
- Contact Second Nature Brands for a full refund.
Contact information for refunds and questions
Second Nature Brands says consumers can reach them by phone or email:
- Phone: +1.800.651.7263
- Monday–Friday: 8:00 AM–8:00 PM ET
- Saturday–Sunday: 9:00 AM–5:00 PM ET
- Email: recall@secondnaturebrandsus.com
Health & fitness note: “Keto” doesn’t equal “risk-free”
Keto-friendly snacks can be convenient for people managing carbs, training schedules, or busy workdays—but this alert is a reminder that label accuracy is non-negotiable, especially for anyone balancing nutrition goals with medical dietary restrictions.
If you or someone in your household has a tree nut or cherry allergy, consider doing a quick sweep of:
- Snack drawers at home and work
- Gym bags and travel kits
- Recent bulk orders or subscription deliveries
Bottom line
If you have a 10-ounce pouch of SECOND NATURE KETO CRUNCH SMART MIX™ with UPC 077034013405 and Best if used by 2/12/2027, do not eat it. Contact Second Nature Brands for a refund and share the alert with anyone who may have purchased the product—especially those with tree nut or cherry allergies.
Source
Welcome to the Consumer Corner section of STM Daily News, your ultimate destination for savvy shopping and informed decision-making! Dive into a treasure trove of insights and reviews covering everything from the hottest toys that spark joy in your little ones to the latest electronic gadgets that simplify your life. Explore our comprehensive guides on stylish home furnishings, discover smart tips for buying a home or enhancing your living space with creative improvement ideas, and get the lowdown on the best cars through our detailed auto reviews. Whether you’re making a major purchase or simply seeking inspiration, the Consumer Corner is here to empower you every step of the way—unlock the keys to becoming a smarter consumer today!
Last Updated on April 11, 2026 by Daily News Staff
April 10, 2026 — NASA’s Artemis II crew has safely returned to Earth, marking the successful completion of the first crewed mission to the Moon’s vicinity in more than 50 years.
Credit: NASA/Joel Kowsky
The Orion spacecraft splashed down in the Pacific Ocean off the coast of California at 5:07 p.m. PDT, carrying NASA astronauts Reid Wiseman, Victor Glover, Christina Koch, and Canadian astronaut Jeremy Hansen back home after a nearly 10-day journey through deep space.
🚀 A Mission for the Record Books
During the mission, the crew traveled a total of 694,481 miles, reaching a maximum distance of 252,756 miles from Earth—farther than any humans have ever gone, surpassing the Apollo 13 record set in 1970.
Launched on April 1 aboard NASA’s powerful Space Launch System (SLS) rocket, Artemis II tested critical systems needed for future missions, including life support, navigation, and deep space communication.
🌕 Science, Exploration, and Stunning Views
While orbiting the Moon, the astronauts captured more than 7,000 images, including views of the lunar far side, a rare solar eclipse, and detailed observations of craters, lava flows, and surface features.
The mission also included scientific experiments to better understand how the human body responds to deep space conditions, helping prepare for longer missions to the Moon and Mars.
🛰️ Safe Return and Recovery
Following splashdown, recovery teams quickly reached the spacecraft and transported the crew by helicopter to the USS John P. Murtha for initial medical evaluations. The astronauts are expected to return to NASA’s Johnson Space Center for further assessments.
🌍 What Comes Next
With Artemis II complete, NASA is now turning its focus to Artemis III, the next mission aimed at landing astronauts on the Moon and establishing a long-term human presence.
The success of Artemis II marks a major step forward in humanity’s return to deep space—and the beginning of a new era of exploration.
For more information on NASA’s Artemis program, visit the official NASA website.
🔗 Source & Further Reading
- NASA Blog: Artemis II Flight Day 10 – Re-entry Live Updates
- NASA Artemis II Mission Overview
- NASA Artemis Program – Return to the Moon
- Orion Spacecraft Details and Technology
- NASA Image and Video Library (Artemis II Photos & Media)
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