There is currently no bird flu vaccine for people. Digicomphoto/ Science Photo Library via Getty ImagesHanna D. Paton, University of Iowa The flu sickens millions of people in the U.S. every year, and the past year has been particularly tough. Although infections are trending downward, the Centers for Disease Control and Prevention has called the winter of 2024-2025 a “high severity” season with the highest hospitalization rate in 15 years. Since early 2024, a different kind of flu called bird flu, formally known as avian influenza, has been spreading in birds as well as in cattle. The current bird flu outbreak has infected 70 Americans and caused two deaths as of April 8, 2025. Public health and infectious disease experts say the risk to people is currently low, but they have expressed concern that this strain of the bird flu virus may mutate to spread between people. As a doctoral candidate in immunology, I study how pathogens that make us sick interact with our immune system. The viruses that cause seasonal flu and bird flu are distinct but still closely related. Understanding their similarities and differences can help people protect themselves and their loved ones.
What is influenza?
The flu has long been a threat to public health. The first recorded influenza pandemic occurred in 1518, but references to illnesses possibly caused by influenza stretch back as as early as 412 B.C., to a treatise called Of the Epidemics by the Greek physician Hippocrates. Today, the World Health Organization estimates that the flu infects 1 billion people every year. Of these, 3 million to 5 million infections cause severe illness, and hundreds of thousands are fatal. Influenza is part of a large family of viruses called orthomyxoviruses. This family contains several subtypes of influenza, referred to as A, B, C and D, which differ in their genetic makeup and in the types of infections they cause. Influenza A and B pose the largest threat to humans and can cause severe disease. Influenza C causes mild disease, and influenza D is not known to infect people. Since the turn of the 20th century, influenza A has caused four pandemics. Influenza B has never caused a pandemic.A notice from Oct. 18, 1918, during the Spanish flu pandemic, about protecting yourself from infection.Illustrated Current News/National Library of Medicine, CC BY An influenza A strain called H1N1 caused the famous 1918 Spanish flu pandemic, which killed about 50 million people worldwide. A related H1N1 virus was responsible for the most recent influenza A pandemic in 2009, commonly referred to as the swine flu pandemic. In that case, scientists believe multiple different types of influenza A virus mixed their genetic information to produce a new and especially virulent strain of the virus that infected more than 60 million people in the U.S. from April 12, 2009, to April 10, 2010, and caused huge losses to the agriculture and travel industries. Both swine and avian influenza are strains of influenza A. Just as swine flu strains tend to infect pigs, avian flu strains tend to infect birds. But the potential for influenza A viruses that typically infect animals to cause pandemics in humans like the swine flu pandemic is why experts are concerned about the current avian influenza outbreak.
Seasonal flu versus bird flu
Different strains of influenza A and influenza B emerge each year from about October to May as seasonal flu. The CDC collects and analyzes data from public health and clinical labs to determine which strains are circulating through the population and in what proportions. For example, recent data shows that H1N1 and H3N2, both influenza A viruses, were responsible for the vast majority of cases this season. Standard tests for influenza generally determine whether illness is caused by an A or B strain, but not which strain specifically. Officials at the Food and Drug Administration use this information to make strain recommendations for the following season’s influenza vaccine. Although the meeting at which FDA advisers were to decide the makeup of the 2026 flu vaccine was unexpectedly canceled in late February, the FDA still released its strain recommendations to manufacturers. The recommendations do not include H5N1, the influenza A strain that causes avian flu. The number of strains that can be added into seasonal influenza vaccines is limited. Because cases of people infected with H5N1 are minimal, population-level vaccination is not currently necessary. As such, seasonal flu vaccines are not designed to protect against avian influenza. No commercially available human vaccines currently exist for avian influenza viruses.
How do people get bird flu?
Although H5N1 mainly infects birds, it occasionally infects people, too. Human cases, first reported in 1997 in Hong Kong, have primarily occurred in poultry farm workers or others who have interacted closely with infected birds. Initially identified in China in 1996, the first major outbreak of H5 family avian flu occurred in North America in 2014-2015. This 2014 outbreak was caused by the H5N8 strain, a close relative of H5N1. The first H5N1 outbreak in North America began in 2021 when infected birds carried the virus across the ocean. It then ripped through poultry farms across the continent.The H5N1 strain of influenza A generally infects birds but has infected people, too.NIAID and CDC/flickr, CC BY In March 2024, epidemiologists identified H5N1 infections in cows on dairy farms. This is the first time that bird flu was reported to infect cows. Then, on April 1, 2024, health officials in Texas reported the first case of a person catching bird flu from infected cattle. This was the first time transmission of bird flu between mammals was documented. As of March 21, 2025, there have been 988 human cases of H5N1 worldwide since 1997, about half of which resulted in death. The current outbreak in the U.S. accounts for 70 of those infections and one death. Importantly, there have been no reports of H5N1 spreading directly from one person to another. Since avian flu is an influenza A strain, it would show up as positive on a standard rapid flu test. However, there is no evidence so far that avian flu is significantly contributing to current influenza cases. Specific testing is required to confirm that a person has avian flu. This testing is not done unless there is reason to believe the person was exposed to sick birds or other sources of infection.
How might avian flu become more dangerous?
As viruses replicate within the cells of their host, their genetic information can get copied incorrectly. Some of these genetic mutations cause no immediate differences, while others alter some key viral characteristics. Influenza viruses mutate in a special way called reassortment, which occurs when multiple strains infect the same cell and trade pieces of their genome with one another, potentially creating new, unique strains. This process prolongs the time the virus can inhabit a host before an infection is cleared. Even a slight change in a strain of influenza can result in the immune system’s inability to recognize the virus. As a result, this process forces our immune systems to build new defenses instead of using immunity from previous infections. Reassortment can also change how harmful strains are to their host and can even enable a strain to infect a different species of host. For example, strains that typically infect pigs or birds may acquire the ability to infect people. Influenza A can infect many different types of animals, including cattle, birds, pigs and horses. This means there are many strains that can intermingle to create novel strains that people’s immune systems have not encountered before – and are therefore not primed to fight. It is possible for this type of transformation to also occur in H5N1. The CDC monitors which strains of flu are circulating in order prepare for that possibility. Additionally, the U.S. Department of Agriculture has a surveillance system for monitoring potential threats for spillover from birds and other animals, although this capacity may be at risk due to staff cuts in the department. These systems are critical to ensure that public health officials have the most up-to-date information on the threat that H5N1 poses to public health and can take action as early as possible when a threat is evident.Hanna D. Paton, PhD Candidate in Immunology, University of Iowa This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Former President Barack Obama recently sparked headlines, social media debates, and a fresh wave of UFO chatter after a brief remark during a podcast interview. The comment quickly ricocheted across news outlets, with many asking: Did Obama just confirm aliens exist? And just as quickly, Donald Trump weighed in.
Let’s unpack what was actually said — and what it means.
🎙️ The Comment That Ignited the Conversation
During a rapid-fire question segment on a podcast hosted by Brian Tyler Cohen, Obama was asked directly:
“Are aliens real?”
Obama’s response:
“They’re real, but I haven’t seen them.”
That short answer fueled immediate speculation. Clips spread online, often stripped of context, with some interpreting the statement as a bombshell confirmation of extraterrestrial life.
🧠 What Obama Meant
Soon after the comment gained traction, Obama clarified his meaning.
His explanation aligned with a position he’s expressed before:
✔ He was referring to the statistical likelihood of life elsewhere in the universe
✔ He was not claiming evidence of alien visitation
✔ He emphasized that during his presidency he saw no proof of extraterrestrial contact
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In other words:
Obama was speaking philosophically and scientifically — not revealing classified information.
This interpretation matches mainstream scientific thinking: given the size of the universe, life beyond Earth is plausible, but confirmed evidence remains elusive.
🛸 Why the Comment Resonated
The remark landed in a cultural moment where:
• Interest in UAPs (Unidentified Aerial Phenomena) is high
• Government transparency around UFO reports has increased
• Space exploration discoveries (exoplanets, water worlds) dominate science news
Even a casual statement from a former president can ignite intense discussion.
🇺🇸 Trump’s Reaction
Former (and current political figure) Donald Trump responded critically.
Trump characterized Obama’s comment as:
• A “mistake”
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• Potentially involving “classified information”
He also reiterated his own stance:
He does not know whether aliens are real.
Trump pivoted the conversation toward disclosure, suggesting he would support or consider declassifying UFO/UAP-related files — a theme that has periodically surfaced in political rhetoric.
⚖️ Politics vs Interpretation
Trump’s reaction highlights how statements about extraterrestrial life often become political flashpoints, even when the original comment is speculative or philosophical.
Key distinction:
Obama’s Clarification
Public Interpretation
Life elsewhere is likely
“Obama confirmed aliens”
No evidence of contact
“Government disclosure”
🔬 The Scientific Reality
Organizations like NASA and the broader research community maintain:
✅ Life beyond Earth → statistically plausible
❓ Intelligent civilizations → unknown
❌ Confirmed alien contact → no verified evidence
Investigations into UAPs consistently conclude:
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• Most sightings have conventional explanations
• Some remain unresolved due to limited data
• None confirmed as extraterrestrial craft
🌌 Why These Stories Keep Captivating Us
Conversations about aliens sit at the intersection of:
✨ Science
🧠 Curiosity
🛸 Mystery
🎭 Pop culture
🏛️ Politics
When a former president comments, the intrigue multiplies.
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📌 Bottom Line
Did Obama say aliens are real?
Yes — but in the sense that life elsewhere in the universe is likely, not that aliens are visiting Earth.
Did he claim evidence?
No.
Trump’s response?
Critical, skeptical, and framed around classification and disclosure.
If you’re fascinated by this topic, you might also enjoy exploring:
• How scientists search for alien life
• What counts as real “evidence”
• Why UFO sightings are so often misinterpreted
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Want me to craft a follow-up article like “How Close Are We to Discovering Alien Life?” 🚀👽
Dive into “The Knowledge,” where curiosity meets clarity. This playlist, in collaboration with STMDailyNews.com, is designed for viewers who value historical accuracy and insightful learning. Our short videos, ranging from 30 seconds to a minute and a half, make complex subjects easy to grasp in no time. Covering everything from historical events to contemporary processes and entertainment, “The Knowledge” bridges the past with the present. In a world where information is abundant yet often misused, our series aims to guide you through the noise, preserving vital knowledge and truths that shape our lives today. Perfect for curious minds eager to discover the ‘why’ and ‘how’ of everything around us. Subscribe and join in as we explore the facts that matter. https://stmdailynews.com/the-knowledge/
Rod: A creative force, blending words, images, and flavors. Blogger, writer, filmmaker, and photographer. Cooking enthusiast with a sci-fi vision. Passionate about his upcoming series and dedicated to TNC Network. Partnered with Rebecca Washington for a shared journey of love and art. View all posts
Why Downtown Los Angeles Feels Small Compared to Other Cities
Downtown Los Angeles often feels “small” compared to other U.S. cities, but that’s only part of the story. With some of the tallest buildings west of the Mississippi and skyline clusters spread across the region, LA’s downtown reflects the city’s unique polycentric identity—one that, if combined, could form a true mega downtown.
Panorama of Los Angeles from Mount Hollywood – California, United States
When people think of major American cities, they often imagine a bustling, concentrated downtown core filled with skyscrapers. New York has Manhattan, Chicago has the Loop, San Francisco has its Financial District. Los Angeles, by contrast, often leaves visitors surprised: “Is this really downtown?”
The answer is yes—and no.
Downtown LA in Context
Compared to other major cities, Downtown Los Angeles (DTLA) is relatively small as a central business district. For much of the 20th century, strict height restrictions capped most buildings under 150 feet, while cities like Chicago and New York were erecting early skyscrapers. LA’s skyline didn’t really begin to climb until the late 1960s.
But history alone doesn’t explain why DTLA feels different. The real story lies in how Los Angeles grew: not as one unified city center, but as a collection of many hubs.
Downtown Los Angeles
A Polycentric City
Los Angeles is famously decentralized. Hollywood developed around the film industry. Century City rose on former studio land as a business hub. Burbank became a studio and aerospace center. Long Beach grew around the port. The Wilshire Corridor filled with office towers and condos.
Unlike other cities where downtown is the place for work, culture, and finance, Los Angeles spread its energy outward. Freeways and car culture made it easy for businesses and residents to operate outside of downtown. The result is a polycentric metropolis, with multiple “downtowns” rather than one dominant core.
A Resident’s Perspective
As someone who lived in Los Angeles for 28 years, I see DTLA differently. While some outsiders describe it as “small,” the reality is that Downtown Los Angeles is still significant. It has some of the tallest buildings west of the Mississippi River, including the Wilshire Grand Center and the U.S. Bank Tower. Over the last two decades, adaptive reuse projects have transformed old office buildings into lofts, while developments like LA Live, Crypto.com Arena, and the Broad Museum have revitalized the area.
In other words, DTLA is large enough—it just plays a different role than downtowns in other American cities.
View of Westwood, Century City, Beverly Hills, and the Wilshire Corridor.
The “Mega Downtown” That Isn’t
A friend once put it to me with a bit of imagination: “If you could magically pick up all of LA’s skyline clusters—Downtown, Century City, Hollywood, the Wilshire Corridor—and drop them together in one spot, you’d have a mega downtown.”
He’s right. Los Angeles doesn’t lack tall buildings or urban energy—it just spreads them out over a vast area, reflecting the city’s unique history, geography, and culture.
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A Downtown That Fits Its City
So, is Downtown LA “small”? Compared to Manhattan or Chicago’s Loop, yes. But judged on its own terms, DTLA is a vibrant hub within a much larger, decentralized metropolis. It’s a downtown that reflects Los Angeles itself: sprawling, diverse, and impossible to fit neatly into the mold of other American cities.
Dive into “The Knowledge,” where curiosity meets clarity. This playlist, in collaboration with STMDailyNews.com, is designed for viewers who value historical accuracy and insightful learning. Our short videos, ranging from 30 seconds to a minute and a half, make complex subjects easy to grasp in no time. Covering everything from historical events to contemporary processes and entertainment, “The Knowledge” bridges the past with the present. In a world where information is abundant yet often misused, our series aims to guide you through the noise, preserving vital knowledge and truths that shape our lives today. Perfect for curious minds eager to discover the ‘why’ and ‘how’ of everything around us. Subscribe and join in as we explore the facts that matter. https://stmdailynews.com/the-knowledge/
Century City: From Hollywood Backlot to Business Hub
Century City, originally part of 20th Century Fox’s backlot, transformed into a prominent business district in Los Angeles during the 1950s amid the decline of cinema. Developer William Zeckendorf envisioned a mixed-use urban center, leading to iconic skyscrapers and establishing the area as a hub for law, finance, and media, blending Hollywood history with modern business.
Before Century City became one of Los Angeles’ premier business districts, it was part of 20th Century Fox’s sprawling backlot, used for filming movies and housing studio operations. By the 1950s, as television rose and movie attendance declined, 20th Century Fox faced financial challenges and decided to sell a portion of its land.
Traffic On 405 Freeway In LA With Century City In The Background
Developer William Zeckendorf envisioned a “city within a city”—a modern, mixed-use urban center with office towers, hotels, and entertainment facilities. Branded Century City, the name paid homage to its studio roots while symbolizing LA’s vision for the future.
The first skyscrapers, including the Gateway West Building, set the tone for the district’s sleek, futuristic skyline. Architects like Welton Becket and Minoru Yamasaki helped shape Century City’s iconic look. Over time, it evolved from Hollywood’s backlot to a corporate and legal hub, attracting law firms, financial institutions, and media companies.
Today, Century City stands as a testament to Los Angeles’ postwar optimism, westward expansion, and multi-centered urban growth—a unique blend of Hollywood history and modern business.
Dive into “The Knowledge,” where curiosity meets clarity. This playlist, in collaboration with STMDailyNews.com, is designed for viewers who value historical accuracy and insightful learning. Our short videos, ranging from 30 seconds to a minute and a half, make complex subjects easy to grasp in no time. Covering everything from historical events to contemporary processes and entertainment, “The Knowledge” bridges the past with the present. In a world where information is abundant yet often misused, our series aims to guide you through the noise, preserving vital knowledge and truths that shape our lives today. Perfect for curious minds eager to discover the ‘why’ and ‘how’ of everything around us. Subscribe and join in as we explore the facts that matter. https://stmdailynews.com/the-knowledge/
Hanna D. Paton, PhD Candidate in Immunology, University of Iowa This article is republished from The Conversation under a Creative Commons license. Read the original article.
