health and wellness
A Genetic Connection to Kidney Disease

How APOL1-mediated kidney disease can impact you, your kidneys and your family
(Family Features) A genetic condition that can cause kidney failure, APOL1-mediated kidney disease (AMKD) represents a group of kidney diseases associated with mutations (changes or variants) in the apolipoprotein L1 (APOL1) genes.
Typically, the APOL1 genes – of which every person has two, one from each parent – create proteins that play a role in immunity. However, some people are born with mutations in one or both genes, and having mutations in both can increase the risk of developing kidney disease and even kidney failure.
In honor of National AMKD Awareness Day on April 30, consider this information from the experts at the American Kidney Fund to better understand the disease and become APOL1 aware.
Understanding Risk Factors
Research shows Black people with kidney disease are more likely to develop kidney failure than any other racial or ethnic group. The reasons for these health disparities include social determinants of health, a higher burden of diabetes and high blood pressure in the Black community, barriers to health care access and genetics.
The APOL1 gene mutations evolved over the past 3,000-10,000 years in people who lived in western and central Africa and are associated with increased protection from a parasite carried by the tse tse fly that causes African sleeping sickness. While protecting from one disease, the mutation – if inherited in both APOL1 genes – is more likely to lead to kidney disease in those of certain African descent, including people who identify as Black, African American, Afro-Caribbean or Latina or Latino.
In fact, an estimated 13% of Black Americans have two APOL1 gene mutations, according to the American Kidney Fund. While not everyone who has two APOL1 mutations will get kidney disease, there is a 1 in 5 chance they will go on to develop AMKD.
Identifying Symptoms
If you have kidney damage, symptoms may not occur until your kidneys are close to failing. As kidney damage worsens, one or more of these symptoms may occur:
- Protein in urine
- Swelling in legs or weight gain
- Feeling weak or tired
- High blood pressure
Should these symptoms occur and you have a family history of kidney disease, talk to a doctor about getting tested for kidney disease, as testing is the only way to determine kidney function. AMKD can cause damage to parts of the kidney that filter blood or, in some cases, cause cells in the kidneys to die, which can lead to damage and scarring that may eventually lead to kidney failure.
Getting a Diagnosis
The only way to know if you have APOL1 gene mutations is to do genetic testing via a blood or saliva sample. Genetic testing may be considered if you have kidney disease and don’t know the cause or if you’re considering donating a kidney. Testing may also be considered if a family member is a carrier for the mutation. If you have questions about genetic testing, discuss your options with a doctor or ask for a referral to a genetic counselor.
Taking Steps to Prevent Kidney Disease
There are currently no treatments available for AMKD. However, there are steps you can take to protect your kidneys and promote general health. Work with your doctor to create a plan to prevent or delay the progression of kidney disease, which may include:
- Doctor visits to check how your kidneys are working through urine and blood tests
- Checking for and managing diabetes and high blood pressure
- A healthy eating plan, which may involve limiting things like sodium (salt)
- Taking prescription medications as directed
- Being active at least 30 minutes each day of the week
- Quitting smoking or using tobacco
If you have the APOL1 gene mutations, you may be able to take part in clinical trials. Trials could provide an opportunity for researchers to develop and test safe treatments for AMKD. Also speak with family members about having genetic testing done if you have the mutation as they may also have it.
Learn more and find additional resources at kidneyfund.org/APOL1aware.
Photo courtesy of Shutterstock
SOURCE:
American Kidney Fund
STM Daily News is a vibrant news blog dedicated to sharing the brighter side of human experiences. Emphasizing positive, uplifting stories, the site focuses on delivering inspiring, informative, and well-researched content. With a commitment to accurate, fair, and responsible journalism, STM Daily News aims to foster a community of readers passionate about positive change and engaged in meaningful conversations. Join the movement and explore stories that celebrate the positive impacts shaping our world.
Discover more from Daily News
Subscribe to get the latest posts sent to your email.
Lifestyle
Be APOL1 Aware and Understand How Genes Impact Kidney Health


- Protein in urine
- Swelling in legs or weight gain
- Feeling weak or tired
- High blood pressure
Discover more from Daily News
Subscribe to get the latest posts sent to your email.
Sports
College Basketball Stars with Personalized Nutrition and Hydration at 2025 Combine in Tampa, Florida
Global Health and Wellness Leader Brings 20 Years of Expertise in Performance Nutrition to Empower Female Athletes LOS ANGELES /PRNewswire/ — Herbalife, a premier health and wellness company, community and platform, today announced it is the Official Nutrition and Hydration Partner of the Lilly 2025 Women’s College All-Star Combine, scheduled for Friday, April 4. The inaugural event will provide basketball players with an unprecedented platform to showcase their talents and gain visibility from scouts and recruiters, opening doors to new opportunities in their careers. With over two decades of experience supporting professional athletes globally, Herbalife will bring its expertise in personalized nutrition and hydration strategies, offering athletes at the combine access to world-class resources and products.
“We are proud to bring over 20 years of experience of fueling athletes to college basketball players,” said Krissy Lines, director of sports performance, nutrition, and education at Herbalife. “Our mission is to deliver personalized nutrition and hydration strategies that empower each athlete to perform at her peak. This is a pivotal moment for these women, not just as athletes, but as leaders in sport, and we’re honored to provide the resources and expertise to help them take the court with confidence, strength, and readiness to shine.”
As the Official Nutrition and Hydration Sponsor, Herbalife will provide participants with expert-led nutrition education designed to address the unique needs of female athletes, including factors like metabolism, muscle mass, and hormonal fluctuations that impact their nutritional and hydration requirements. In addition, Herbalife’s science-backed products, including the Herbalife24 NSF Certified for Sport®* line, will be available to both participants and spectators. This product line is specifically formulated to help replenish essential nutrients lost through sweat, optimizing hydration, endurance, and recovery.
“Having worked closely with Herbalife on several initiatives supporting athletes of all levels, I’ve seen first-hand how their expertise in nutrition education can make a significant difference in an athlete’s performance,” said Joe Abunassar, president of Herbalife IMPACT Basketball Center in Las Vegas and on-court instructor at the combine. “This combine is an incredible opportunity for these athletes, and with Herbalife’s support, they will be well-equipped to perform at their highest level. This is a great step for women in basketball, and I’m excited to see what these athletes can achieve.”
In addition to supporting the combine as its Official Nutrition and Hydration Sponsor, Herbalife is also the Official Nutrition and Hydration Sponsor of the Lilly Women’s College All-Star Game, which will showcase 20 of the nation’s top collegiate basketball players as they compete one final time before transitioning to the next phase of their careers.
“Herbalife’s expertise in nutrition and hydration will ensure that athletes are fully prepared to showcase their talents,” said Mark Starsiak, senior vice president at Intersport, the event organizers. “We are excited to provide this platform for women to take center stage in front of scouts and coaches, and we are grateful for Herbalife’s support in making this event a reality.”
For over two decades, Herbalife has been dedicated to empowering female athletes around the world, currently sponsoring more than 50 women across a variety of sports. The company’s journey began with its very first sponsored athlete, a female athlete, and has continued to provide women in sports with the support they need to succeed. Herbalife provides athletes with access to nutritionists and dietitians, premium products, and other resources that are often lacking in female sports – giving them the tools they need to perform at their best. Through this continued support, Herbalife is helping to elevate women in sports and inspire the next generation of female athletes.
For updates on how Herbalife is fueling athletes around the world, follow @Herbalife, @HerbalifeUSA on social media.
*Certified for Sport® is a registered trademark of NSF International.
About Herbalife Ltd.
Herbalife is a premier health and wellness company, community and platform that has been changing people’s lives with great nutrition products and a business opportunity for its independent distributors since 1980. The Company offers science-backed products to consumers in more than 95 markets through entrepreneurial distributors who provide one-on-one coaching and a supportive community that inspires their customers to embrace a healthier, more active lifestyle to live their best life.
For more information, visit https://ir.herbalife.com.
About Intersport
Intersport is an award-winning agency that fills the empty space between marketing campaigns and consumers—helping brands make more meaningful connections. Its industry-leading team offers expert insights in content marketing, experiential marketing, hospitality, partnership consulting and platform development. The Chicago-based agency also owns and operates events across the professional and collegiate sports landscape, including basketball, football, golf, pickleball and volleyball. Intersport has been headquartered in Chicago since its inception in 1985 and has an additional office in Detroit. Learn more at www.intersport.global and on social media (LinkedIn, Instagram and Facebook).
SOURCE Herbalife
Discover more from Daily News
Subscribe to get the latest posts sent to your email.
Lifestyle
Connected Communities: Reducing the Impact of Isolation in Rural Areas


Boost Your Social Connections
Take a proactive approach to combatting social isolation and loneliness with these everyday actions that can promote stronger social ties.- Invest time in nurturing your relationships through consistent, frequent and high-quality engagement with others. Take time each day to reach out to a friend or family member.
- Minimize distractions during conversation to increase the quality of the time you spend with others. For instance, don’t check your phone during meals with friends, important conversations and family time.
- Seek out opportunities to serve and support others, either by helping your family, co-workers, friends or people in your community or by participating in community service.
- Be responsive, supportive and practice gratitude. As you practice these behaviors, others are more likely to reciprocate, strengthening social bonds, improving relationship satisfaction and building social capital.
- Participate in social and community groups such as religious, hobby, fitness, professional and community service organizations to help foster a sense of belonging, meaning and purpose.
- Seek help during times of struggle with loneliness or isolation by reaching out to a family member, friend, counselor, health care provider or the 988 crisis line.
Discover more from Daily News
Subscribe to get the latest posts sent to your email.
-
Urbanism2 years ago
Signal Hill, California: A Historic Enclave Surrounded by Long Beach
-
News2 years ago
Diana Gregory Talks to us about Diana Gregory’s Outreach Services
-
Senior Pickleball Report2 years ago
The Absolute Most Comfortable Pickleball Shoe I’ve Ever Worn!
-
STM Blog2 years ago
World Naked Gardening Day: Celebrating Body Acceptance and Nature
-
Senior Pickleball Report2 years ago
ACE PICKLEBALL CLUB TO DEBUT THEIR HIGHLY ANTICIPATED INDOOR PICKLEBALL FRANCHISES IN THE US, IN EARLY 2023
-
Travel2 years ago
Unique Experiences at the CitizenM
-
Automotive2 years ago
2023 Nissan Sentra pricing starts at $19,950
-
Senior Pickleball Report2 years ago
“THE PEOPLE’S CHOICE AWARDS OF PICKLEBALL” – VOTING OPEN