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Enterobacter bugandensis: A Superbug from the Stars and Its Implications for Space Exploration

NASA has discovered *Enterobacter bugandensis*, a multidrug-resistant superbug aboard the ISS, posing significant health risks to astronauts.

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Enterobacter bugandensis

In a discovery that sounds straight out of a sci-fi horror film, NASA recently announced the identification of a new multidrug-resistant bacterium aboard the International Space Station (ISS). Dubbed Enterobacter bugandensis, this superbug not only raises eyebrows but also presents significant health risks for astronauts venturing into the great unknown.

The Discovery: An Unsettling Find

The identification of E. bugandensis is a chilling reminder of the unexpected challenges that come with space exploration. This bacterium has mutated in the isolated, unique environment of outer space, rendering it genetically distinct from its Earth-bound relatives. The result? A formidable adversary for human health, capable of resisting common antibiotics that would typically combat its terrestrial counterparts.

Collaborative research conducted by IIT Madras and NASA revealed a wealth of information about this superbug, encompassing its prevalence, distribution, and colonization patterns in the microgravity environment of the ISS. The results are not just startling; they compel us to rethink our approach to microbial management in space.

Sci-Fi or Reality? The Horror Unfolds

Imagine a creature lurking within the confines of the ISS, much like an antagonist from a John Carpenter film or the ominous Hunter Seeker robo-wasp from Dune: Part One. E. bugandensis has thrived in the station’s isolated systems, benefiting from the absence of natural competition. The bacterium’s ability to acquire iron and its interactions with other microorganisms have facilitated its extraordinary resilience.

Scientists have uncovered remarkable genomic adaptations that bolster the superbug’s ability to withstand the extreme conditions of space. These adaptations diverge significantly from those found in the more benign strains of bacteria typically encountered on Earth, emphasizing the unique challenges posed by microgravity.

Intimidating Adaptations for Survival

The incredible adaptability of microorganisms is well-documented; however, E. bugandensis takes this to a new level. While most microbes aboard the ISS exist in a state of relative stability, this superbug has undergone genomic changes that allow it to thrive in a microgravity environment. Such transformations are not merely survival tactics; they underscore the bacterium’s unique evolutionary path, setting it apart from any counterparts on our home planet.

As scientists delve deeper into the genetic nuances of E. bugandensis, they reveal a complex web of interactions with other microbial inhabitants of the ISS. This interplay not only ensures the bug’s survival but also raises alarms about the potential health risks it poses to astronauts, particularly concerning respiratory infections.

Astronaut Immunity: A Critical Concern

One of the most pressing issues surrounding E. bugandensis is the compromised immune systems of astronauts during long-duration missions. The microgravity environment induces various physiological changes that may leave astronauts more vulnerable to infections. With the presence of this resilient superbug aboard the ISS, the danger of illness becomes an even greater concern, especially given the limited access to medical facilities in space.

To mitigate these risks, NASA is prioritizing ongoing studies of E. bugandensis and other microorganisms aboard the ISS. Understanding the behavior and adaptations of these space-dwelling microbes is crucial for ensuring the health and safety of astronauts on future missions to the Moon, Mars, and beyond.

Earthbound Implications: A Cautionary Tale

While the immediate focus is on the health risks posed to astronauts, the existence of E. bugandensis also raises questions about potential implications for Earth. Could a superbug adapted to the harsh realities of space somehow find its way back to our planet? While this scenario may sound like the plot of a science fiction thriller, it underscores the need for vigilance in monitoring microbial life in extraterrestrial environments.

Dr. Kasthuri Venkateswaran of NASA’s Jet Propulsion Laboratory, along with a collaborative team from IIT Madras, has been at the forefront of this research. Their work not only highlights the challenges of microbial management in space but also emphasizes the need for robust biosecurity measures to protect both astronauts and life on Earth.

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Conclusion: A New Chapter in Space Exploration

The discovery of Enterobacter bugandensis serves as a stark reminder of the complexities and unforeseen challenges of space exploration. As we journey further into the cosmos, understanding and managing the microbial life we encounter will be paramount for the health and safety of astronauts. In this new frontier, every unexpected finding—be it a superbug or a new form of life—requires careful consideration and proactive measures to ensure a safe return to Earth.

As we look to the stars, we must also remain grounded in our commitment to understanding the intricate web of life that exists, even in the most unwelcoming environments. The future of space exploration may depend on it.

Learn more about Enterobacter bugandensis in the peer-reviewed article published in Nature. https://www.nature.com/articles/s41598-018-23069-z

The science section of our news blog STM Daily News provides readers with captivating and up-to-date information on the latest scientific discoveries, breakthroughs, and innovations across various fields. We offer engaging and accessible content, ensuring that readers with different levels of scientific knowledge can stay informed. Whether it’s exploring advancements in medicine, astronomy, technology, or environmental sciences, our science section strives to shed light on the intriguing world of scientific exploration and its profound impact on our daily lives. From thought-provoking articles to informative interviews with experts in the field, STM Daily News Science offers a harmonious blend of factual reporting, analysis, and exploration, making it a go-to source for science enthusiasts and curious minds alike. https://stmdailynews.com/category/science/

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The Long Track Back

Why Downtown Los Angeles Feels Small Compared to Other Cities

Downtown Los Angeles often feels “small” compared to other U.S. cities, but that’s only part of the story. With some of the tallest buildings west of the Mississippi and skyline clusters spread across the region, LA’s downtown reflects the city’s unique polycentric identity—one that, if combined, could form a true mega downtown.

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Last Updated on February 18, 2026 by Daily News Staff

Downtown Los Angeles

Panorama of Los Angeles from Mount Hollywood – California, United States

When people think of major American cities, they often imagine a bustling, concentrated downtown core filled with skyscrapers. New York has Manhattan, Chicago has the Loop, San Francisco has its Financial District. Los Angeles, by contrast, often leaves visitors surprised: “Is this really downtown?”

The answer is yes—and no.

Downtown LA in Context

Compared to other major cities, Downtown Los Angeles (DTLA) is relatively small as a central business district. For much of the 20th century, strict height restrictions capped most buildings under 150 feet, while cities like Chicago and New York were erecting early skyscrapers. LA’s skyline didn’t really begin to climb until the late 1960s.

But history alone doesn’t explain why DTLA feels different. The real story lies in how Los Angeles grew: not as one unified city center, but as a collection of many hubs.

Downtown Los Angeles

Downtown Los Angeles

A Polycentric City

Los Angeles is famously decentralized. Hollywood developed around the film industry. Century City rose on former studio land as a business hub. Burbank became a studio and aerospace center. Long Beach grew around the port. The Wilshire Corridor filled with office towers and condos.

Unlike other cities where downtown is the place for work, culture, and finance, Los Angeles spread its energy outward. Freeways and car culture made it easy for businesses and residents to operate outside of downtown. The result is a polycentric metropolis, with multiple “downtowns” rather than one dominant core.

A Resident’s Perspective

As someone who lived in Los Angeles for 28 years, I see DTLA differently. While some outsiders describe it as “small,” the reality is that Downtown Los Angeles is still significant. It has some of the tallest buildings west of the Mississippi River, including the Wilshire Grand Center and the U.S. Bank Tower. Over the last two decades, adaptive reuse projects have transformed old office buildings into lofts, while developments like LA Live, Crypto.com Arena, and the Broad Museum have revitalized the area.

In other words, DTLA is large enough—it just plays a different role than downtowns in other American cities.

Downtown Los Angeles

View of Westwood, Century City, Beverly Hills, and the Wilshire Corridor.

The “Mega Downtown” That Isn’t

A friend once put it to me with a bit of imagination: “If you could magically pick up all of LA’s skyline clusters—Downtown, Century City, Hollywood, the Wilshire Corridor—and drop them together in one spot, you’d have a mega downtown.”

He’s right. Los Angeles doesn’t lack tall buildings or urban energy—it just spreads them out over a vast area, reflecting the city’s unique history, geography, and culture.

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A Downtown That Fits Its City

So, is Downtown LA “small”? Compared to Manhattan or Chicago’s Loop, yes. But judged on its own terms, DTLA is a vibrant hub within a much larger, decentralized metropolis. It’s a downtown that reflects Los Angeles itself: sprawling, diverse, and impossible to fit neatly into the mold of other American cities.

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Dive into “The Knowledge,” where curiosity meets clarity. This playlist, in collaboration with STMDailyNews.com, is designed for viewers who value historical accuracy and insightful learning. Our short videos, ranging from 30 seconds to a minute and a half, make complex subjects easy to grasp in no time. Covering everything from historical events to contemporary processes and entertainment, “The Knowledge” bridges the past with the present. In a world where information is abundant yet often misused, our series aims to guide you through the noise, preserving vital knowledge and truths that shape our lives today. Perfect for curious minds eager to discover the ‘why’ and ‘how’ of everything around us. Subscribe and join in as we explore the facts that matter.  https://stmdailynews.com/the-knowledge/

 

 

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The Knowledge

Century City: From Hollywood Backlot to Business Hub

Century City, originally part of 20th Century Fox’s backlot, transformed into a prominent business district in Los Angeles during the 1950s amid the decline of cinema. Developer William Zeckendorf envisioned a mixed-use urban center, leading to iconic skyscrapers and establishing the area as a hub for law, finance, and media, blending Hollywood history with modern business.

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Before Century City became one of Los Angeles’ premier business districts, it was part of 20th Century Fox’s sprawling backlot, used for filming movies and housing studio operations. By the 1950s, as television rose and movie attendance declined, 20th Century Fox faced financial challenges and decided to sell a portion of its land.

Discover the origin of Century City, where 20th Century Fox’s historic backlot transformed into one of Los Angeles’ premier business districts. Explore how Hollywood history shaped LA’s modern skyline.
Traffic On 405 Freeway In LA With Century City In The Background

Developer William Zeckendorf envisioned a “city within a city”—a modern, mixed-use urban center with office towers, hotels, and entertainment facilities. Branded Century City, the name paid homage to its studio roots while symbolizing LA’s vision for the future.

The first skyscrapers, including the Gateway West Building, set the tone for the district’s sleek, futuristic skyline. Architects like Welton Becket and Minoru Yamasaki helped shape Century City’s iconic look. Over time, it evolved from Hollywood’s backlot to a corporate and legal hub, attracting law firms, financial institutions, and media companies.

Today, Century City stands as a testament to Los Angeles’ postwar optimism, westward expansion, and multi-centered urban growth—a unique blend of Hollywood history and modern business.


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Dive into “The Knowledge,” where curiosity meets clarity. This playlist, in collaboration with STMDailyNews.com, is designed for viewers who value historical accuracy and insightful learning. Our short videos, ranging from 30 seconds to a minute and a half, make complex subjects easy to grasp in no time. Covering everything from historical events to contemporary processes and entertainment, “The Knowledge” bridges the past with the present. In a world where information is abundant yet often misused, our series aims to guide you through the noise, preserving vital knowledge and truths that shape our lives today. Perfect for curious minds eager to discover the ‘why’ and ‘how’ of everything around us. Subscribe and join in as we explore the facts that matter.  https://stmdailynews.com/the-knowledge/


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Local governments provide proof that polarization is not inevitable

Local politics help mitigate national polarization by focusing on concrete issues like infrastructure and community needs rather than divisive symbolic debates. A survey indicates that local officials experience less partisanship, as interpersonal connections foster recognition of shared interests. This suggests that reducing polarization is possible through collaboration and changes in election laws.

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Ribbon cutting ceremony with mascots present. Local officials get to participate in events such as ribbon cuttings, celebrating projects they may have helped make happen.
Local officials get to participate in events such as ribbon cuttings, celebrating projects they may have helped make happen. NHLI/Eliot J. Schechter via Getty Images

Lauren Hall, Rochester Institute of Technology

When it comes to national politics, Americans are fiercely divided across a range of issues, including gun control, election security and vaccines. It’s not new for Republicans and Democrats to be at odds over issues, but things have reached a point where even the idea of compromising appears to be anathema, making it more difficult to solve thorny problems.

But things are much less heated at the local level. A survey of more than 1,400 local officials by the Carnegie Corporation and CivicPulse found that local governments are “largely insulated from the harshest effects of polarization.” Communities with fewer than 50,000 residents proved especially resilient to partisan dysfunction.

Why this difference? As a political scientist, I believe that lessons from the local level not only open a window onto how polarization works but also the dynamics and tools that can help reduce it.

Problems are more concrete

Local governments deal with concrete issues – sometimes literally, when it comes to paving roads and fixing potholes. In general, cities and counties handle day-to-day functions, such as garbage pickup, running schools and enforcing zoning rules. Addressing tangible needs keeps local leaders’ attention fixed on specific problems that call out for specific solutions, not lengthy ideological debates.

By contrast, a lot of national political conflict in the U.S. involves symbolic issues, such as debates about identity and values on topics such as race, abortion and transgender rights. These battles are often divisive, even more so than purely ideological disagreements, because they can activate tribal differences and prove more resistant to compromise.

Three men site in chairs on a dais in front of a banner reading
When mayors come together, they often find they face common problems in their cities. Gathered here, from left, are Jerry Dyer of Fresno, Calif., John Ewing Jr. of Omaha, Neb., and David Holt of Oklahoma City. AP Photo/Kevin Wolf

Such arguments at the national level, or on social media, can lead to wildly inaccurate stereotypes about people with opposing views. Today’s partisans often perceive their opponents as far more extreme than they actually are, or they may stereotype them – imagining that all Republicans are wealthy, evangelical culture warriors, for instance, or conversely being convinced that all Democrats are radical urban activists. In terms of ideology, the median members of both parties, in fact, look similar.

These kinds of misperceptions can fuel hostility.

Local officials, however, live among the human beings they represent, whose complexity defies caricature. Living and interacting in the same communities leads to greater recognition of shared interests and values, according to the Carnegie/CivicPulse survey.

Meaningful interaction with others, including partisans of the opposing party, reduces prejudice about them. Local government provides a natural space where identities overlap.

People are complicated

In national U.S. politics today, large groups of individuals are divided not only by party but a variety of other factors, including race, religion, geography and social networks. When these differences align with ideology, political disagreement can feel like an existential threat.

Such differences are not always as pronounced at the local level. A neighbor who disagrees about property taxes could be the coach of your child’s soccer team. Your fellow school board member might share your concerns about curriculum but vote differently in presidential elections.

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A large group of reporters surround Minneapolis Mayor Jacob Frey.
Mayors can find themselves caught up in national debates, as did Minneapolis Mayor Jacob Frey over the Trump administration’s immigration enforcement policies in his city. AP Photo/Kevin Wolf

These cross-cutting connections remind us that political opponents are not a monolithic enemy but complex individuals. When people discover they have commonalities outside of politics with others holding opposing views, polarization can decrease significantly.

Finally, most local elections are technically nonpartisan. Keeping party labels off ballots allows voters to judge candidates as individuals and not merely as Republicans or Democrats.

National implications

None of this means local politics are utopian.

Like water, polarization tends to run downhill, from the national level to local contests, particularly in major cities where candidates for mayor and other office are more likely to run as partisans. Local governments also see culture war debates, notably in the area of public school instruction.

Nevertheless, the relative partisan calm of local governance suggests that polarization is not inevitable. It emerges from specific conditions that can be altered.

Polarization might be reduced by creating more opportunities for cross-partisan collaboration around concrete problems. Philanthropists and even states might invest in local journalism that covers pragmatic governance rather than partisan conflict. More cities and counties could adopt changes in election law that would de-emphasize party labels where they add little information for voters.

Aside from structural changes, individual Americans can strive to recognize that their neighbors are not the cardboard cutouts they might imagine when thinking about “the other side.” Instead, Americans can recognize that even political opponents are navigating similar landscapes of community, personal challenges and time constraints, with often similar desires to see their roads paved and their children well educated.

The conditions shaping our interactions matter enormously. If conditions change, perhaps less partisan rancor will be the result.

Lauren Hall, Associate professor of Political Science, Rochester Institute of Technology

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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The Bridge is a section of the STM Daily News Blog meant for diversity, offering real news stories about bona fide community efforts to perpetuate a greater good. The purpose of The Bridge is to connect the divides that separate us, fostering understanding and empathy among different groups. By highlighting positive initiatives and inspirational actions, The Bridge aims to create a sense of unity and shared purpose. This section brings to light stories of individuals and organizations working tirelessly to promote inclusivity, equality, and mutual respect. Through these narratives, readers are encouraged to appreciate the richness of diverse perspectives and to participate actively in building stronger, more cohesive communities.

https://stmdailynews.com/the-bridge


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