health and wellness
FDA Approves Palforzia for Young Children with Peanut Allergy: A New Era of Allergy Management
In a significant advancement for families grappling with peanut allergies, the U.S. Food and Drug Administration (FDA) has expanded the approval of Palforzia (Peanut [Arachis hypogaea] Allergen Powder-dnfp) to include children aged 1 to 3 years. This decision marks a pivotal step in the management of peanut allergies, a condition affecting millions of children and their families. Let’s delve into what this means for young patients and their caregivers.
Understanding Palforzia
Palforzia is an oral immunotherapy product designed to help individuals with a confirmed diagnosis of peanut allergy build tolerance to peanuts over time. The treatment works by gradually introducing small amounts of peanut protein, thereby reducing the risk of severe allergic reactions, including anaphylaxis, that can occur with accidental exposure.
Originally approved in January 2020 for individuals aged 4 to 17 years, the recent expansion to include toddlers offers hope to a younger demographic. This means that children as young as 1 year old can now embark on a treatment regimen aimed at mitigating the severity of allergic reactions to peanuts.
The Treatment Journey: Initiation, Up-Dosing, and Maintenance
The treatment process with Palforzia involves several stages:
- Initiation of Treatment: The process begins with a carefully monitored initiation phase, where the child is introduced to Palforzia under the supervision of a healthcare provider. This stage is crucial to ensure safety and to monitor for any potential reactions.
- Up-Dosing: After the initial phase, the dosage of Palforzia is gradually increased over several weeks. This up-dosing phase helps the child’s immune system adjust to the presence of peanut allergens, aiming to build tolerance.
- Maintenance: Once the appropriate dose is achieved, the child enters the maintenance phase, where they continue to take Palforzia daily. This phase is designed to sustain the tolerance that has been developed during the up-dosing period.
Ongoing Peanut Avoidance
It’s vital to note that while Palforzia helps in building tolerance, it does not eliminate the need for strict peanut avoidance in the child’s diet. Families must continue to be vigilant and ensure that their child avoids peanuts and peanut-containing products, as exposure can still lead to allergic reactions.
Safety Measures: Risk Evaluation and Mitigation Strategy (REMS)
Given the potential for anaphylaxis associated with peanut allergies, the FDA has implemented a Risk Evaluation and Mitigation Strategy (REMS) for Palforzia. This strategy includes specific safety measures to ensure that the treatment is used safely:
- Healthcare Provider Training: Providers must be trained in the management of allergic reactions and the safe administration of Palforzia.
- Patient Monitoring: Children receiving Palforzia must be monitored closely during the initiation and up-dosing phases to quickly address any adverse reactions.
- Patient and Caregiver Education: Comprehensive education is provided to families about the signs of allergic reactions, emergency response protocols, and the importance of continued peanut avoidance.
Looking Ahead
The expansion of Palforzia’s approval to younger children represents a hopeful development for families affected by peanut allergies. With proper medical supervision and adherence to safety protocols, this treatment can significantly reduce the risk of severe allergic reactions, allowing children to navigate their environments with greater confidence and safety.
As research continues to evolve in the field of food allergies, the FDA’s decision underscores the ongoing commitment to providing innovative solutions for managing allergic conditions. For families, this means a brighter future, filled with more options for treatment and, ultimately, a better quality of life for their children.
If you think Palforzia might be right for your child, consult with a healthcare provider who specializes in allergy management to discuss the benefits and considerations of this groundbreaking treatment.
STM Daily News is a vibrant news blog dedicated to sharing the brighter side of human experiences. Emphasizing positive, uplifting stories, the site focuses on delivering inspiring, informative, and well-researched content. With a commitment to accurate, fair, and responsible journalism, STM Daily News aims to foster a community of readers passionate about positive change and engaged in meaningful conversations. Join the movement and explore stories that celebrate the positive impacts shaping our world.
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Child Health
How to Supplement Breastfeeding with Bottle Feeding
(Family Features) For moms who breastfeed, the idea of introducing a bottle can feel like a big change. Whether supplementing for personal reasons, returning to work or ensuring adequate nourishment, the transition between breast and bottle can be eased with the right approach – and the right tools. Here’s how to make this process smooth and stress-free for both you and your baby.
Begin Gradually and Mindfully
When supplementing with a bottle, it’s important to start slowly, ideally once breastfeeding is well-established, usually after the first few weeks. Begin by replacing one breastfeeding session with a bottle feeding and gradually increase as needed. This gradual transition helps your baby adapt to the new experience without feeling overwhelmed or confused. If you have questions or concerns about introducing bottle feeding, your pediatrician is an excellent resource.
Prioritize the Right Bottle Design
Using a bottle that closely mirrors the breastfeeding experience can make all the difference in a smooth transition. For example, NUK’s Perfect Match Bottle, from the No. 1 hospital-trusted brand (based on industry data) for feeding, is specifically designed to bridge the gap between breast and bottle feeding. Its ultra-soft silicone nipple is shaped to mimic the feel of a mother’s breast, adapting to your baby’s unique palate for a familiar, comforting feeding experience. This breast-like comfort can make the transition seamless and intuitive for babies. Additionally, it features an advanced anti-colic venting system that minimizes air intake, reducing digestive discomfort and keeping your baby comfortable for a calm, enjoyable feeding time – without the hassle of extra parts to clean.
Maintain Familiar Feeding Conditions
Convincing a breastfed baby to take a bottle can take a bit of patience. Ease the transition by creating an environment similar to breastfeeding conditions to provide a comforting and familiar experience for your baby. Hold your baby close, make eye contact and create a quiet environment to establish a sense of security. Also, plan for bottle feedings when you know your baby is ready to eat, but not overly hungry or fussy.
Use a Safe and Convenient Feeding System
One common concern when supplementing is ensuring milk is served at a safe temperature. With a built-in SafeTemp indicator that changes color if the milk is too hot, the NUK Perfect Match bottle gives parents peace of mind. This feature can simplify the feeding process, making it more intuitive for busy caregivers.
Enlist Help with Bottle Feeding
Sometimes, a baby may be more likely to accept a bottle when offered by someone other than the breastfeeding parent. A partner or caregiver can introduce bottle feeding, helping your baby adapt without associating it directly with breastfeeding. Once established, you can alternate who offers the bottle.
Stay Flexible and Patient
Every baby’s journey is unique, and patience is key. If challenges arise during supplementation, such as bottle refusal or digestive changes, seek guidance from your pediatrician or a lactation consultant. They can help tailor the approach to your baby’s needs.
Discover the future of feeding and learn more at nuk-usa.com.
SOURCE:
NUK
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
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Lifestyle
Sex on TV: Less impact on teens than you might think
Research shows that, despite fears, exposure to sexual media does not meaningfully correlate with teens and sexual behavior. Instead, parental guidance remains crucial in shaping teens’ understanding of sexuality.
Christopher J. Ferguson, Stetson University
Few people would doubt that sex is ubiquitous in media – whether movies, television, music or books – and that teens today have unprecedented access to all of it. It’s often taken for granted that this easy access to “sexy media” has an influence on teenage sexuality.
Specifically, the worry is that teens may have sex earlier or engage in higher-risk sexual activities such as having multiple partners or exposing themselves to potential pregnancies or STDs. In 2010 the American Academy of Pediatrics even published a position paper claiming that sexually explicit media could promote risky teen sexual behavior.
But government data find that teens are actually waiting longer than in the past to have sex. And teen pregnancy rates are at historic lows. How is it possible that sexy media has such a pernicious effect even as teen sexuality is becoming healthier?
I’ve spent more than a decade researching how media – like video games or advertising – influences youth behavior. What fascinates me is how society interacts with media, often embracing salacious content while simultaneously blaming it for societal problems, whether real or imagined.
So my colleagues and I decided to look at the research on sexy media and teenage sexual behavior to see how the strong the link between the two is.
Sexy media doesn’t predict sexual behavior
Despite the common assumptions about sex in the media and its alleged effects on teens, the evidence behind the link is weak. Some studies find evidence for a small effect (perhaps in some circumstances but not others), while others find no evidence for any effect.
One reason the evidence may not be conclusive is that there are practical and ethical limitations to conducting research. We can’t run experiments where teens watch different TV shows and we wait around to see who has sex. This means research often relies on self-reported data. What we do is ask teens to report on their sexual behavior and their media preferences, as well as other variables we might like to control for (such as personality or family environment) and see if correlations exist.
With this in mind, my colleagues Patrick Markey at Villanova and Danish researcher Rune Nielsen and I conducted a meta-analysis of 22 studies with over 22,000 participants that examine the correlation between sexy media and teenage sexual behavior. A meta-analysis lets us look for commonalities in the results, and is something that had not been done previously with this pool of research.
All of the studies in the meta-analysis looked at depictions of sexual situations, nudity, partial nudity or explicit discussions of sex in television shows or movies easily accessible to minors (and thus excluded pornography).
In particular, we were curious to see whether sexy media predicted teen sexual behavior once other variables had been controlled. For instance, maybe boys tend to watch sexier media and also are more sexually risk-taking. Or perhaps youth who are more liberal in terms of personality are more open both to sexy media and earlier sexual initiation. Perhaps a difficult family background is the underlying key to understanding any correlation between media use habits and actual sexual behavior.
Ultimately, this is what we found. Once other factors such as family environment, personality or even gender were controlled, sexy media exposure did not meaningfully correlate with teen sexual behavior.
Contrary to common fears, sexy media doesn’t seem to have any practical significance for when teens first have sex or start other sexual behaviors. This lack of correlation is a warning sign we might be on the wrong track in trying to blame media for teen sexual risk-taking.
Why doesn’t media influence teens?
There are numerous theories that discuss how individuals and media interact. However, many older media effects theories didn’t consider why people were drawn to media, how they processed it, or what they hoped to get from it. Such theories assumed viewers simply irrationally and purposelessly imitated what they saw. Most of the papers we examined in our meta-analysis were tests of these basic, automatic, media effects theories.
In the past few years, some scholars (myself included) have specifically called for the retirement of these older media effects theories. This is because the evidence increasingly suggests that fictional media such as feature movies or sitcoms media is too remote to have a clear impact on consumers’ behavior, especially compared to families and peers.
In addition, emerging evidence suggests that young children process fictional media differently from real events. If small children are able to process a difference between fictional events and real events, we can assume that teens don’t really expect media to reflect reality.
Our results regarding the limited impact of media also fit with the observations from societal data. Despite a plethora of sexual media available to teens, a crisis of risky teen sexual behavior has not emerged.
We watch what we’re interested in watching
Newer models of media use suggest that it is the individuals who consume media, not the media itself, who are the driving agents of behavior. Evidence suggests that users seek out and interpret media according to what they want to get from it, rather than passively imitating it.
People don’t generally accidentally watch media, sexual or otherwise, but are motivated to do so because of preexisting desires.
For instance, some recent studies have indicated that youth seek out media that fit with preexisting motives, called a selection effect, but that media don’t necessarily lead to further problem behaviors. For example, research suggests that some teens who are already aggressive might be interested in violent video games, but playing such games doesn’t make kids more aggressive.
That’s a point that sometimes seems ignored when we talk about teens and sex. Interest in sex is a largely biologically motivated process; fictional media really isn’t required. Teens will become interested in sex all on their own.
Parents have more influence than the media
Parents can rest a bit easier since the evidence suggests that media isn’t a primary driver of teen sexuality.
To the extent media has any impact at all, it is likely only in a vacuum left by adults reluctant to talk to kids about sex, especially the stuff kids really want to know.
How do you ask someone out on a date and how do you handle it if they say no? What does sex feel like? When is it OK to have sex? What are the risks and how do you avoid them? In the face of patient, empathic and informative discussions about sex by adults kids trust, the media likely has little influence.
Ultimately, whether media have salacious or more conscientious portrayals of sexuality, we should not expect media to replace conversations with youth by parents, guardians and educators.
I’m not suggesting everyone run out and buy “50 Shades of Grey” for their teen, but if teens happen to come across it (and they will), it’s not the end of the world.
The important thing for parents is to talk to their kids.
Christopher J. Ferguson, Associate Professor of Psychology, Stetson University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
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Food and Beverage
Cinnamon, spice and ‘everything nice’ – why lead-tainted cinnamon products have turned up on shelves, and what questions consumers should ask
A Consumer Reports investigation revealed alarming lead levels in ground cinnamon, prompting concerns over safety, especially for children and pregnant women.
Katarzyna Kordas, University at Buffalo
Spices bring up feelings of comfort, cultural belonging and holidays. They can make our homes smell amazing and our food taste delicious. They can satisfy our cravings, expand our culinary horizons and help us eat things that we might normally dislike. Spices have health-enhancing properties and, in medicine, have been used to heal people since the ancient times.
Recently, however, spices have been getting a bad rep.
In September 2024, Consumer Reports, a nonprofit organization created to inform consumers about products sold in the U.S., investigated more than three dozen ground cinnamon products and found that 1 in 3 contained lead levels above 1 part per million, enough to trigger a recall in New York, one U.S. state that has published guidelines for heavy metals in spices.
The Food and Drug Administration issued three alerts throughout 2024, warning consumers about lead in certain brands of cinnamon products. Such notices rightfully put consumers on alert and have people wondering if the spice products they buy are safe – or not. https://www.youtube.com/embed/QxAwznMht8M?wmode=transparent&start=0 A Consumer Reports investigation of more than three dozen ground cinnamon products found that 1 in 3 contain lead levels above 1 part per million.
As an environmental epidemiologist with training in nutritional sciences, I have investigated the relationship between nutritional status, diets and heavy metal exposures in children.
There are several things consumers should be thinking about when it comes to lead – and other heavy metals – in cinnamon.
Why is lead found in cinnamon?
Most people are familiar with cinnamon in two forms – sticks and ground spice. Both come from the dried inner bark of the cinnamon tree, which is harvested after a few years of cultivation. For the U.S. market, cinnamon is largely imported from Indonesia, Vietnam, Sri Lanka, India and China.
One way that lead could accumulate in cinnamon tree bark is when trees are cultivated in contaminated soil. Lead can also be introduced in cinnamon products during processing, such as grinding.
When ground cinnamon is prepared, some producers may add lead compounds intentionally to enhance the weight or color of the product and, thus, fetch a higher sale price. This is known as “food adulteration,” and products with known or suspected adulteration are refused entry into the U.S.
However, in the fall of 2023, approximately 600 cases of elevated blood lead levels in the U.S., defined as levels equal to or above 3.5 micrograms per deciliter – mostly among children – were linked to the consumption of certain brands of cinnamon apple sauce. The levels of lead in cinnamon used to manufacture those products ranged from 2,270 to 5,110 parts per million, indicating food adulteration. The manufacturing plant was investigated by the FDA.
More broadly, spices purchased from vendors in the U.S. have lower lead levels than those sold abroad.
There is some evidence that cinnamon sticks have lower lead levels than ground spice. Lead levels in ground cinnamon sold in the U.S. and analyzed by Consumer Reports ranged from 0.02 to 3.52 parts per million. These levels were at least 1,500 times lower than in the adulterated cinnamon.
There are no federal guidelines for lead or other heavy metals in spices. New York state has proposed even stricter guidelines than its current level of 1 part per million, which would allow the New York Department of Agriculture and Markets to remove products from commerce if lead levels exceed 0.21 parts per million.
What does it mean that ‘the dose makes the poison’?
The current FDA guideline on daily intake of lead from diets overall is to limit lead intake to 2.2 micrograms per day for children. For women of reproductive age, this value is 8.8 micrograms.
The lead dose we are exposed to from foods depends on the level of lead in the food and how much of that food we eat. Higher doses mean more potential harm. The frequency with which we consume foods – meaning daily versus occasionally – also matters.
For spices like cinnamon, the amount and frequency of consumption depends on cultural traditions and personal preference. For many, cinnamon is a seasonal spice; others use it year-round in savory dishes or sauces.
Cinnamon is beloved in baked goods. Take a cinnamon roll recipe calling for 1.5 tablespoons (slightly less than 12 grams) of the spice. If a recipe yields 12 rolls, each will have around 1 gram of cinnamon. In the Consumer Reports investigation, some cinnamon products were classified as “okay to use” or “best to use.”
The highest value of lead in cinnamon products in the “okay to use” category was 0.87 parts per million, and in the “best to use” category, it was 0.15 parts per million. A child would have to consume 2.5 or more rolls made with the “okay to use” cinnamon to exceed the FDA guideline on limiting lead intake from foods to 2.2 micrograms per day, assuming that no other food contained lead. To exceed this guideline with “best to use” cinnamon, a child would have to eat 15 or more rolls.
Can cinnamon contribute to elevated blood lead levels?
Because of lead’s effects on development in early life, the greatest concern is for exposure in young children and pregnant women. Lead is absorbed in the small intestine, where it can latch onto cellular receptors that evolved to carry iron and other metals.
The impact of a contaminated spice on a person’s blood lead level depends on the dose of exposure and the proportion of lead available for intestinal absorption. For several spices, the proportion of available lead was 49%, which means that about half of the lead that is ingested will be absorbed.
Lead absorption is higher after a fast of three hours or more, and skipping breakfast may contribute to higher blood lead levels in children.
People who have nutritional deficiencies, such as iron deficiency, also tend to absorb more lead and have higher blood lead levels. This is because our bodies compensate for the deficiency by producing more receptors to capture iron from foods. Lead takes advantage of the additional receptors to enter the body. Young children and pregnant women are at higher risk for developing iron deficiency, so there is good reason for vigilance about lead in the foods they consume.
Studies show that among children with lead poisoning in the U.S., contaminated spices were one of several sources of lead exposure. Studies that estimate blood lead levels from statistical models suggest that consuming 5 micrograms of lead or more from spices daily could substantially contribute to elevated blood lead levels.
For occasional or seasonal consumption, or lower levels of contamination, more research is needed to understand how lead in spices would affect lead levels in the blood.
For people who have other sources of lead in their homes, jobs or hobbies, additional lead from foods or spices may matter more because it adds to the cumulative dose from multiple exposure sources.
How to test for elevated blood lead levels
The Centers for Disease Control and Prevention recommends that children at risk for lead exposure get a blood lead test at 1 and 2 years of age. Older children can also get tested. Finger-prick screening tests are often available in pediatric offices, but results may need to be confirmed in venous blood if the screening result was elevated.
Adults in the U.S. are not routinely tested for lead exposure, but concerned couples who plan on having children should talk to their health care providers.
What to consider when using or buying cinnamon or other spices
If the product is on an FDA Alert or the Consumer Reports “don’t use” list, discard it.
Other questions to consider are:
- Does your household use spices frequently and in large amounts?
- Do young children or pregnant women in your household consume spices?
- Do you typically consume spices on breakfast foods or beverages?
If the answer to any of these questions is yes, then buy good-quality products, from large, reputable sellers. Think about using cinnamon sticks if possible.
And continue to enjoy spices!
Katarzyna Kordas, Associate Professor of Epidemiology and Environmental Health, University at Buffalo
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
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