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FDA Moves Forward with Mail-back Envelopes for Opioid Analgesics Dispensed in Outpatient Settings

Agency Continues to Take Steps to Reduce New Cases of Opioid Use Disorder

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Agency Continues to Take Steps to Reduce New Cases of Opioid Use Disorder

Today, the U.S. Food and Drug Administration announced it is requiring manufacturers of opioid analgesics dispensed in outpatient settings to make prepaid mail-back envelopes available to outpatient pharmacies and other dispensers as an additional opioid analgesic disposal option for patients.

“Expanding impactful opioid disposal options, such as mail-back envelopes and in-home disposal, for patients to safely and securely dispose of their unused opioid medications is part of the agency’s comprehensive approach to addressing the overdose crisis,” said FDA Commissioner Robert M. Califf, M.D. “We believe these efforts will not only increase convenient disposal options for many Americans, but also reduce unfortunate opportunities for nonmedical use, accidental exposure, overdose and potential new cases of opioid use disorder. We’re pleased to take this first critical step to increase mail-back envelope options in partnership with the U.S. Postal Service.” 

The FDA issued notice today to all manufacturers of opioid analgesics used in outpatient settings that they are required to submit the proposed modification to the Opioid Analgesic Risk Evaluation and Mitigation Strategy (OA REMS) within 180 days of the date of the notification letter. The agency anticipates approval of the modified REMS in 2024. When implemented, outpatient pharmacies and other dispensers will have the option to order prepaid mail-back envelopes from opioid analgesic manufacturers, which they may then provide to patients prescribed opioid analgesics. The REMS modification also requires manufacturers to develop educational materials for patients on safe disposal of opioid analgesics, which outpatient pharmacies and other dispensers may also provide to patients. 

This action follows a Federal Register notice issued in April 2022 that sought public comment on a potential modification of the OA REMS to require that mail-back envelopes be dispensed and education on safe disposal be provided with opioid analgesics dispensed in an outpatient setting. 

Patients commonly report having unused opioid analgesics following surgical procedures and many Americans gain access to opioids through friends or relatives who have unused opioids. Data show educating patients about disposal options may increase the disposal rate of unused opioids and that providing a disposal option along with education could further increase that rate. 

Currently, there are multiple mail-back envelope programs operating in the U.S. and mail-back envelopes are commercially available from multiple entities. There are long-standing regulations and policies, under the Drug Enforcement Administration and United States Postal Service, in place to ensure that mail-back envelopes are nondescript, fit for purpose, and can safely and securely transport unused medicines from the patient’s home to the location where they will be destroyed.

“The U.S. Postal Service is proud to partner with the FDA to expand the use of mail-back envelopes as a safe and secure disposal option for prescription opioid analgesics,” said Postal Service Chief Customer and Marketing Officer and Executive Vice President Steven Monteith. “Serving nearly 165 million addresses each day, with more than 31,000 retail locations across the country, the Postal Service makes it convenient for Americans to dispose of unused prescription drugs to help prevent accidental exposure and overdose.” 

The FDA continues to consider additional ways to increase safe disposal of unused opioid analgesics. Specifically, the agency is exploring whether manufacturers of opioid analgesic should also be required to make in-home disposal products available to patients who are prescribed opioid analgesics. In an effort to further evaluate this potential option, the agency will participate in the workshop, Defining and Evaluating In-Home Drug Disposal Systems for Opioid AnalgesicsExternal Link Disclaimer, to examine current in-home disposal options hosted by the National Academies of Sciences, Engineering and Medicine’s (NASEM’s) Forum on Drug Discovery, Development, and Translation in June 2023. The FDA has also issued a Federal Register Notice to seek information and comments from the public to aid the agency’s assessment of in-home disposal methods.

These collective efforts are part of the agency’s implementation of the FDA Overdose Prevention Framework that aims to prevent drug overdoses and reduce deaths through impactful and creative actions. The FDA remains focused on responding to all facets of substance use, misuse, substance use disorders, overdose and death in the U.S. through the four priorities of the framework, including; supporting primary prevention by eliminating unnecessary initial prescription drug exposure and inappropriate prolonged prescribing; encouraging harm reduction through innovation and education; advancing development of evidence-based treatments for substance use disorders; and protecting the public from unapproved, diverted or counterfeit drugs presenting overdose risks.

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Source: FDA

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BREAKING: Artemis II Successfully Launches on Historic Moon Mission

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Last Updated on April 2, 2026 by Daily News Staff

🕒 [UPDATE] Orion Performs Translunar Injection Burn

The spacecraft has completed its critical engine burn, sending Artemis II on a trajectory toward the Moon. This marks the official start of its deep space journey.


Rocket launching into the sky. BREAKING: Artemis II Successfully Launches on Historic Moon Mission
Source: NASA | Artemis II launch coverage and official mission updates

Artemis II Successfully Launches

CAPE CANAVERAL, Fla. — NASA has successfully launched its Artemis II mission, marking the first crewed journey toward the Moon in more than 50 years.

The powerful Space Launch System (SLS) rocket lifted off from Kennedy Space Center on April 1, carrying four astronauts on a 10-day mission around the Moon and back. 

On board are Commander Reid Wiseman, Pilot Victor Glover, Mission Specialist Christina Koch, and Canadian astronaut Jeremy Hansen. The mission is already being hailed as a major milestone in NASA’s effort to return humans to deep space. 

Shortly after liftoff, the Orion spacecraft successfully reached orbit and deployed its solar arrays, beginning its journey that will eventually send the crew on a translunar trajectory toward the Moon. 

NHQ202603310001medium
Source: NASA/Bill Ingalls

Artemis II is a lunar flyby mission, meaning astronauts will not land but will travel farther from Earth than any human mission in decades while testing critical systems needed for future landings. 

The mission also marks several historic firsts, including the first woman and the first person of color—Victor Glover—to travel into lunar space. 

NASA says the mission is a key step toward future lunar landings and long-term plans to establish a human presence on the Moon later this decade. 


🛰️ Artemis II Mission Timeline

The 10-day Artemis II mission follows a carefully planned trajectory from Earth to the Moon and back:

  • Day 1: Launch and Earth orbit
  • Day 1–2: Translunar injection burn
  • Days 2–4: Deep space travel
  • Days 4–5: Lunar flyby
  • Days 5–8: Return to Earth
  • Days 9–10: Reentry and splashdown

For official updates and in-depth mission details, visit the following trusted sources:


🧾 Sources

  • NASA official launch coverage and mission updates
  • NASA Artemis II press materials and briefings
  • NASA Kennedy Space Center launch operations updates

Stay with STM Daily News for live updates on Artemis II.

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Breaking: Chuck Norris Dies at 86

Chuck Norris Dies at 86: Chuck Norris, legendary martial artist and star of Walker, Texas Ranger, has died at age 86 following a reported medical emergency.

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Last Updated on March 20, 2026 by Daily News Staff

Legendary martial artist and actor Chuck Norris has died at the age of 86, according to statements released by his family on Friday.

Chuck Norris Hollywood Star
Chuck Norris’ star on the Hollywood Walk of Fame. Image Credit: Like_the_Grand_Canyon/ Wikipedia

Norris reportedly passed away peacefully while surrounded by loved ones. The news comes shortly after reports surfaced that he had been hospitalized in Hawaii following a medical emergency. Details regarding the cause of death have not yet been publicly disclosed.

Best known for his role in the long-running television series Walker, Texas Ranger, Norris became a global icon through his martial arts expertise and action film career. His influence extended beyond Hollywood, shaping pop culture and inspiring generations of fans worldwide.

Over a career spanning decades, Norris starred in numerous action films and television projects, building a reputation as one of the most recognizable figures in the genre.

This is a developing story. STM Daily News will continue to provide updates as more information becomes available.

Related Coverage & Sources
People: Chuck Norris Dies at 86

TMZ: Chuck Norris Hospitalized After Medical Emergency
Euronews: Reports on Chuck Norris Medical Emergency
WLIX: Family Confirms Death of Chuck Norris

Note: This is a developing story. Source details and confirmations may be updated as more information becomes available.

Note: This is a developing story. Source details and confirmations may be updated as more information becomes available.

STM Daily News delivers timely breaking news coverage that keeps readers informed on the stories shaping their communities and the wider world. From local developments and national headlines to business, technology, entertainment, and public interest reporting, STM Daily News provides fast, accessible coverage with a clear focus on relevance, accuracy, and impact.


Live Updates

March 20, 2026 – 7:00 AM (PT): Initial reports confirm the death of Chuck Norris at age 86, according to family statements.

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Earlier: Reports indicated Norris had been hospitalized in Hawaii following a medical emergency. Additional details are still emerging.

This live blog will be updated as new information becomes available.

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🌕 Blood Moon Over Arizona: Total Lunar Eclipse Visible in Phoenix on March 3, 2026

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Last Updated on March 2, 2026 by Daily News Staff

Early risers in Arizona are in for a celestial show.

A total lunar eclipse will be visible in Phoenix on March 3, 2026. Here are exact viewing times, what to expect, and how to watch the Blood Moon in Arizona.

On Tuesday, March 3, 2026, a total lunar eclipse will be visible across much of North America — including Phoenixand the Valley. During this event, the Moon will pass completely into Earth’s shadow, turning a deep copper-red color often called a “Blood Moon.”

Here’s what you need to know.


Geometry of a Lunar Eclipse.svg
A schematic diagram of the shadow cast by Earth. Within the umbra, the central region, the planet totally shields direct sunlight. In contrast, within the penumbra, the outer portion, the sunlight is only partially blocked. SunMoon, and Earth sizes and distances between them not to scale.

🌍 What Is a Total Lunar Eclipse?

A total lunar eclipse happens when the Sun, Earth, and Moon align perfectly, with Earth positioned directly between the Sun and the Moon. As the Moon moves into Earth’s darkest shadow (the umbra), it doesn’t disappear — instead, it glows red.

That reddish color comes from sunlight filtering through Earth’s atmosphere — essentially, we’re seeing all the world’s sunrises and sunsets projected onto the Moon at once.


🕒 Phoenix Viewing Times (MST)

Arizona does not observe Daylight Saving Time in March, so these times are in Mountain Standard Time (MST).

  • 1:44 a.m. – Penumbral eclipse begins (subtle dimming begins)
  • 2:50 a.m. – Partial eclipse begins (Earth’s shadow becomes clearly visible)
  • 4:04 a.m. – Totality begins 🌕
  • 4:34 a.m. – Greatest eclipse
  • 5:03 a.m. – Totality ends
  • 6:18 a.m. – Partial eclipse ends
  • 7:20 a.m. – Penumbral eclipse ends
Lunar eclipse contact diagram.svg
Vectorised by User:Sushant savla from the work by Tomruen – File:Lunar eclipse contact diagram.png

The most dramatic portion — totality — lasts nearly one hour.


🌅 Where to Look in Phoenix

The eclipse happens in the pre-dawn hours, so the Moon will be low in the western sky as it sets.

For the best view:

  • Find a location with a clear western horizon
  • Avoid city light glare if possible
  • Consider desert viewpoints, parks, or elevated areas around the Valley

Because the Moon will be setting as the Sun begins to rise, the backdrop of early morning twilight could make for stunning photography.

AdobeStock 284042140

🔭 Do You Need Special Equipment?

No.

Unlike a solar eclipse, lunar eclipses are completely safe to view with the naked eye. However:

  • Binoculars enhance color detail
  • A small telescope reveals subtle shadow gradients
  • A tripod and DSLR or smartphone with night mode can capture impressive images

🌎 Why This Eclipse Matters

This will be one of the most accessible celestial events of 2026 for Arizona residents. Total lunar eclipses don’t happen every year in the same location, and the timing — just before sunrise — adds dramatic visual contrast.

If skies are clear, Phoenix could have a spectacular view.


📌 Quick Viewing Reminder for Phoenix

Set your alarm for around 3:45 a.m.

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Step outside by 4:00 a.m.

Look west

Watch the Moon turn red

No tickets. No crowds. Just the sky putting on a show.


For more science, space, and Arizona skywatching coverage, visit STM Daily News.


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