Health
Help Wanted: How clinical trials help fight disease
(Family Features) Clinical trials are necessary for finding new ways of preventing, detecting or treating diseases, but often, limited participation creates challenges for meeting clinical trial goals. Despite decades of effort and strategies to identify and address barriers to recruiting and enrolling study participants, recruitment challenges persist, particularly among women, older adults and diverse patient populations.
Clinical trials
“Potential study participants are reluctant to get involved for a variety of reasons, including the time commitment, lack of clarity regarding safeguards for their well-being and concerns about how their medical condition will be handled during the study,” said Alan Moss, MD, chief scientific officer with the Crohn’s & Colitis Foundation, the leading nonprofit organization focused on both research and support of people living with inflammatory bowel disease (IBD). “Taking part in a clinical trial gives patients an opportunity to access new therapies and can help shape future treatment, including how diseases are diagnosed, treated and even prevented.”
Learning more about the important role clinical trials play in health care may ultimately help you or someone you love find a new treatment or manage a condition, such as IBD, more effectively.
Importance of Clinical Trials
Finding a treatment that relieves patients’ symptoms and helps induce and maintain remission is important. However, these treatments wouldn’t be available without clinical trials. In fact, all U.S. Food & Drug Administration (FDA)-approved medicines currently available on the market are the result of clinical trials and the patients who participated in them. When enrollment targets aren’t reached due to low patient participation, there may be delays in the drug approval process.
What You Should Know
There are plenty of reasons to consider participating in a clinical trial, especially if you’re looking for further options to treat a serious condition. Taking part in a clinical trial is a big step, so it’s important to be well-informed.
- Safety: Investigational treatments must be studied extensively before the FDA will approve them. Each trial follows thorough protocols to ensure the health and safety of its participants. Additionally, patients are followed continuously throughout a trial to monitor their health.
- Eligibility: Who can participate in a clinical trial depends greatly on the specific limits of the study. Each clinical trial has its own goals to achieve, which means different trials have different criteria for patients to meet in order to enroll. Some trials are for patients who have moderate to severe disease and others may seek patients with mild disease. Other trials look for patients without any diagnosis. Prior to enrolling in a trial, a research coordinator will review your complete medical history to see if you meet the inclusion criteria.
- Treatment: When you decide to enroll in a clinical trial, you may have access to the study drug as a form of treatment. Typically, participants will not know if they are receiving the study drug during the trial. This helps reduce potential biases and ensures the fairness of the trial. However, all participants are monitored closely. If there is any change in your medical condition while participating in the study, the research staff will inform you immediately and discuss the situation.
- Cost: The majority of clinical trials are federally or privately funded, so there is typically no cost to participants. While federal law requires most health insurance plans to cover the majority of routine patient care costs associated with clinical trials, there are some costs you may incur, such as travel, gas, parking, child care and time away from work. Trial sponsors commonly cover these costs, as well as any non-routine patient care that isn’t covered by insurance. However, it’s a good idea to get a clear understanding of how the trial you’re considering would handle these expenses.
- Leaving the study: At any point you wish to drop out of the trial, you can, and for any reason. In that case, it’s common for a research coordinator to ask you to complete a final visit and schedule follow-up visits, if needed, to ensure you do not experience any side effects.
How to Learn More
If you’re interested in participating in a clinical trial, it’s important to go to trusted sources to learn more and ask questions. For example, the Crohn’s & Colitis Foundation can point you toward clinical trial opportunities. Your doctor’s office can also be a good source of information about local studies.
If you’re hesitant about joining a trial involving a treatment but are eager to help, you might consider other types of research studies, such as prevention, diagnostic, screening or quality of life trials instead.
Once you identify a clinical trial that interests you and you may be eligible for, contact the research coordinator to learn more. You’ll also want to discuss the study in greater detail with your doctor and talk to loved ones within your support system who may have questions or helpful insight to consider.
Visit crohnscolitisfoundation.org/clinical-trials-community to learn more about IBD clinical trials and find opportunities near you.
Understanding IBD
Inflammatory bowel disease (IBD) affects nearly 1 in 100 people living in the United States, according to a study led by the Crohn’s & Colitis Foundation. IBD is an umbrella term used to describe disorders that cause chronic inflammation of the gastrointestinal (GI) tract.
Symptoms include diarrhea, as well as abdominal pain, nausea, fever, loss of appetite, fatigue and, at times, rectal bleeding. No single test can confirm IBD, which includes Crohn’s disease and ulcerative colitis. There are currently no cures for IBD. Medication and managing your diet and nutrition are two of the most common treatment recommendations.
Photos courtesy of Shutterstock
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Crohn’s & Colitis Foundation
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Why the First Year Behind the Wheel is the Most Dangerous: Data Shows Teen Drivers 3 Times More Likely to be in Fatal Crash
Teen drivers are significantly at risk of fatal crashes, with those aged 16-19 being nearly three times more likely to be involved in accidents than older drivers. The first year of driving presents heightened dangers, but with proper preparation, including coaching, technology, and smart insurance, families can mitigate these risks and promote safety.
Why the First Year Behind the Wheel is the Most Dangerous: Data Shows Teen Drivers 3 Times More Likely to be in Fatal Crash
(Feature Impact) The driver’s license photo may be slightly awkward, but the milestone is unforgettable. For families, a newly licensed teen means independence, busy schedules and a new set of responsibilities.
Motor vehicle crashes remain one of the leading causes of death for U.S. teens, according to the Centers for Disease Control and Prevention (CDC). Data from the National Highway Traffic Safety Administration shows drivers ages 16-19 are nearly three times more likely to be involved in a fatal crash than drivers 20 and older, per mile driven.
The statistics are serious, but they’re also manageable.
“With the right preparation, teen driving doesn’t have to feel overwhelming,” said Susan Irace, manager, divisional claims at Mercury Insurance. “Experience is what young drivers are building. Parents can help shorten that learning curve with structure, technology and smart coverage decisions.”
Why the First Year Matters
Federal safety data shows crash risk is highest in a teen’s first year of independent driving. Night driving, teen passengers and distracted driving increase that risk – while seat belts, graduated licensing laws and supervised practice significantly reduce it.
In 2023, more than 2,800 teens ages 13-19 were killed in motor vehicle crashes nationwide, according to the CDC. However, teen crash rates have declined over time thanks to safer vehicles, graduated driver licensing programs and greater awareness of distracted driving.
Ways to Reduce Teen Driving Risk
The experts at Mercury Insurance encourage families to focus on preparation rather than panic.
1. Coach Early and Often
- Log supervised driving time in different conditions – highways, rain, nighttime
- Create a simple written driving agreement outlining expectations
- Limit teen passengers during the first year
- Make seatbelts non-negotiable
2. Let Technology Help
- Choose vehicles with safety features like automatic emergency braking and blind-spot monitoring
- Use telematics or safe-driving feedback tools to reinforce good habits
- Activate smartphone “Do Not Disturb While Driving” settings
3. Review Insurance Before the Keys Change Hands
- Add teens to your insurance policy promptly
- Revisit liability limits to protect family assets
- Ask about good student and driver training discounts
“Insurance is about preparation, not fear,” Irace said. “When families combine active coaching with the right coverage, they’re setting their teen up for safer miles ahead.”
Preparation Turns Risks into Confidence
The first solo drive is a milestone, but preparation determines what comes next. By pairing common-sense coaching with today’s vehicle safety technology and thoughtful insurance planning, families can support independence while managing risk responsibly.
For more teen driver safety tips and coverage guidance, visit MercuryInsurance.com/resources.
Photos courtesy of Shutterstock
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Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
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Last Updated on March 11, 2026 by Daily News Staff
Shelia R. Cotten, Clemson University
What is the first thing you do in the morning after you awaken? Many people immediately check their phones for notifications of messages, alerts and social media updates by their social ties.
Ninety-seven percent of U.S. adults report owning a cellphone, with 90% reporting that they own a smartphone.
While some researchers and media outlets portray phone use as detrimental, the reality is that the effects of technology use, including phones, vary depending on multiple factors. These include the amount, type, timing and purpose of that use. What is best for one group may not be best for another when thinking about technology use.
As a researcher who studies technology use and quality of life, I can offer some advice to hopefully help you thrive in a phone-saturated world. Some people may struggle with how to effectively use smartphones in their daily lives. And many people use their phones more than they think they do or more than they would like at times.
1. Monitor your use on a weekly basis
If the hours per day are increasing, think about why this is the case and whether this increased use is helping or hurting your everyday activities. An aspect of digital literacy is understanding your usage patterns.
2. Consider how you can use these devices to make your life easier
Using a smartphone can help people access online information, schedule appointments, obtain directions, communicate through a variety of mechanisms and potentially be in constant contact with their social ties.
This availability and access to information and social ties can be beneficial and help people juggle work and family responsibilities. However, it may also be related to work intensification, information overload, decreased well-being and the blurring of work/nonwork boundaries.
Weighing the pros and cons of use may help you understand when your phone use is beneficial versus detrimental.
3. Silence nonessential notifications and alerts
Do you really need to know that an old friend from high school messaged you on Facebook at that particular moment?
4. Select particular times during the day for social media
Be deliberate about when you allow yourself to use your phone for social media and other activities. Knowing these times each day may help you concentrate as well as help you to use your phone in more useful and productive ways.
5. Avoid phone use at bedtime
Don’t look at your phone last thing before going to sleep or first thing when you awaken. Have you ever checked email one last time before going to sleep, only to find a message that gets your mind racing and ends up impeding your rest?
6. Choose when not to use your phone
Set times and situations when you are not going to use your phone.
Some of my research has shown that using your phone when in the presence of others who are not using devices, particularly older adults, can be perceived as rude, deter communication and induce distress. My colleagues and I termed this situation the physical-digital divide.
7. Find your own phone-use balance
Don’t compare yourself with others in terms of amount of use but be cognizant of when your use is beneficial versus perhaps leading you to feel stressed or distracted.
8. Moderate phone-as-distraction
Using your phone as a distraction is OK, but do it in moderation. If you find yourself constantly turning to your phone when you are bored or working on something that is hard, try to find ways to maintain your focus and overcome the challenges you are experiencing.
9. Set boundaries
Let your immediate social ties know that you are not going to be checking your phone constantly. While people often expect immediate responses when they message others, the reality is that the majority of messages do not need an immediate response.
10. Be a savvy consumer of online information
This is not exclusive to phones, but it is relevant given the proportion of people who report using their mobile phones and other digital devices to access news and social media. In the era of mis- and disinformation, being critical of information found online is a necessity.
These suggestions can help you to be more cognizant of how much you are using your phone as well as the reasons you are using it. It’s important for your well-being to be a critical consumer of technology and the information you glean from using your devices, particularly your ever-present mobile phone.
Shelia R. Cotten, Provost’s Distinuished Professor of Sociology, Anthropology and Criminal Justice and Communication, Clemson University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.
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Study Links Agent Orange Exposure to Higher Risk of Rare Melanoma
A study revealed that U.S. veterans exposed to Agent Orange are at increased risk of developing acral melanoma, a rare skin cancer located in areas not typically exposed to sunlight. With higher odds of diagnosis and poorer prognosis, early detection in veterans is vital for effective treatment and improved outcomes.
Last Updated on March 9, 2026 by Daily News Staff
(Feature Impact) A new study found U.S. veterans exposed to Agent Orange face a higher risk of developing a rare and often overlooked form of melanoma that appears on the hands and feet, and under the nails.
Researchers reported in “JAMA Dermatology” that veterans with documented exposure to the herbicide had significantly higher odds of developing acral melanoma, a subtype of skin cancer that forms on the palms, soles and nail beds.
Unlike most melanomas, which are associated with ultraviolet radiation, acral melanoma develops in areas not typically exposed to the sun. It can resemble a bruise under a toenail or a dark patch on the bottom of a foot – locations that are easily missed and not commonly associated with skin cancer.
Because of its unusual appearance and location, acral melanoma is often diagnosed at later stages, when treatment is more difficult and survival rates are lower.
The researchers analyzed 20 years of Veterans Health Administration data, comparing more than 1,200 veterans diagnosed with acral melanoma with more than 5,000 veterans without melanoma. Veterans exposed to Agent Orange had about 30% higher odds of developing the disease.
The findings suggest Agent Orange may be an underrecognized risk factor for acral melanoma, particularly for veterans who may not view themselves as at risk for skin cancer because of limited sun exposure or darker skin tones.
“Identifying exposures that may increase risk can help inform earlier recognition and, ultimately, earlier diagnosis when treatment is most effective,” said Marc Hurlbert, chief executive officer of the Melanoma Research Alliance and a principal investigator on the study.
Senior author Dr. Rebecca I. Hartman of Brigham and Women’s Hospital said acral melanoma behaves differently from other melanomas and often responds less well to current therapies.
“Acral melanoma has a poorer prognosis than the more common cutaneous melanoma because it is often diagnosed at later stages,” Hartman said. “Identifying risk factors is critical to improving detection and outcomes.”
Agent Orange was used extensively during the Vietnam War and exposure has been linked to several cancers and chronic illnesses. These findings add to evidence the herbicide may also affect the skin in ways not reflected in traditional melanoma awareness efforts.
Acral melanoma has also been associated with sex, race and ethnicity, and prior skin lesions. Researchers said the study supports treating the disease as distinct from sun-driven melanomas that dominate public education campaigns.
For veterans, the research highlights the importance of examining less visible areas of the body, including the bottoms of the feet, between the toes and under the nails. Changes in nail color, dark streaks or unexplained spots on the palms or soles should be evaluated by a health care provider, especially for those with known Agent Orange exposure.
Researchers said the findings could help guide future screening strategies for higher-risk populations and encourage further study of why acral melanoma differs biologically from other skin cancers.
Find more information at curemelanoma.org.
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