Connect with us

Health

Help Wanted: How clinical trials help fight disease

Published

on

Clinical trials

(Family Features) Clinical trials are necessary for finding new ways of preventing, detecting or treating diseases, but often, limited participation creates challenges for meeting clinical trial goals. Despite decades of effort and strategies to identify and address barriers to recruiting and enrolling study participants, recruitment challenges persist, particularly among women, older adults and diverse patient populations.

Clinical trials

“Potential study participants are reluctant to get involved for a variety of reasons, including the time commitment, lack of clarity regarding safeguards for their well-being and concerns about how their medical condition will be handled during the study,” said Alan Moss, MD, chief scientific officer with the Crohn’s & Colitis Foundation, the leading nonprofit organization focused on both research and support of people living with inflammatory bowel disease (IBD). “Taking part in a clinical trial gives patients an opportunity to access new therapies and can help shape future treatment, including how diseases are diagnosed, treated and even prevented.”

Learning more about the important role clinical trials play in health care may ultimately help you or someone you love find a new treatment or manage a condition, such as IBD, more effectively.

Importance of Clinical Trials
Finding a treatment that relieves patients’ symptoms and helps induce and maintain remission is important. However, these treatments wouldn’t be available without clinical trials. In fact, all U.S. Food & Drug Administration (FDA)-approved medicines currently available on the market are the result of clinical trials and the patients who participated in them. When enrollment targets aren’t reached due to low patient participation, there may be delays in the drug approval process.

What You Should Know
There are plenty of reasons to consider participating in a clinical trial, especially if you’re looking for further options to treat a serious condition. Taking part in a clinical trial is a big step, so it’s important to be well-informed.

  • Safety: Investigational treatments must be studied extensively before the FDA will approve them. Each trial follows thorough protocols to ensure the health and safety of its participants. Additionally, patients are followed continuously throughout a trial to monitor their health.
  • Eligibility: Who can participate in a clinical trial depends greatly on the specific limits of the study. Each clinical trial has its own goals to achieve, which means different trials have different criteria for patients to meet in order to enroll. Some trials are for patients who have moderate to severe disease and others may seek patients with mild disease. Other trials look for patients without any diagnosis. Prior to enrolling in a trial, a research coordinator will review your complete medical history to see if you meet the inclusion criteria.
  • Treatment: When you decide to enroll in a clinical trial, you may have access to the study drug as a form of treatment. Typically, participants will not know if they are receiving the study drug during the trial. This helps reduce potential biases and ensures the fairness of the trial. However, all participants are monitored closely. If there is any change in your medical condition while participating in the study, the research staff will inform you immediately and discuss the situation.
  • Cost: The majority of clinical trials are federally or privately funded, so there is typically no cost to participants. While federal law requires most health insurance plans to cover the majority of routine patient care costs associated with clinical trials, there are some costs you may incur, such as travel, gas, parking, child care and time away from work. Trial sponsors commonly cover these costs, as well as any non-routine patient care that isn’t covered by insurance. However, it’s a good idea to get a clear understanding of how the trial you’re considering would handle these expenses.
  • Leaving the study: At any point you wish to drop out of the trial, you can, and for any reason. In that case, it’s common for a research coordinator to ask you to complete a final visit and schedule follow-up visits, if needed, to ensure you do not experience any side effects.

How to Learn More
If you’re interested in participating in a clinical trial, it’s important to go to trusted sources to learn more and ask questions. For example, the Crohn’s & Colitis Foundation can point you toward clinical trial opportunities. Your doctor’s office can also be a good source of information about local studies.

If you’re hesitant about joining a trial involving a treatment but are eager to help, you might consider other types of research studies, such as prevention, diagnostic, screening or quality of life trials instead.

Once you identify a clinical trial that interests you and you may be eligible for, contact the research coordinator to learn more. You’ll also want to discuss the study in greater detail with your doctor and talk to loved ones within your support system who may have questions or helpful insight to consider.

Visit crohnscolitisfoundation.org/clinical-trials-community to learn more about IBD clinical trials and find opportunities near you.

Advertisement
image 101376000 12222003

Understanding IBD
Inflammatory bowel disease (IBD) affects nearly 1 in 100 people living in the United States, according to a study led by the Crohn’s & Colitis Foundation. IBD is an umbrella term used to describe disorders that cause chronic inflammation of the gastrointestinal (GI) tract.

Symptoms include diarrhea, as well as abdominal pain, nausea, fever, loss of appetite, fatigue and, at times, rectal bleeding. No single test can confirm IBD, which includes Crohn’s disease and ulcerative colitis. There are currently no cures for IBD. Medication and managing your diet and nutrition are two of the most common treatment recommendations.

Photos courtesy of Shutterstock

collect?v=1&tid=UA 482330 7&cid=1955551e 1975 5e52 0cdb 8516071094cd&sc=start&t=pageview&dl=http%3A%2F%2Ftrack.familyfeatures
SOURCE:
Crohn’s & Colitis Foundation

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.


Discover more from Daily News

Subscribe to get the latest posts sent to your email.

Health

Daylight saving time and early school start times cost billions in lost productivity and health care expenses

Daylight saving time disrupts sleep, leading to increased heart attacks, accidents, and mental health issues. Advocating for permanent standard time and later school start times could significantly enhance public health and reduce economic costs.

Published

on

Daylight saving time
Daylight saving time kicks in on March 9, 2025, but some say it leads to more heart attacks, depression and car accidents. Lord Henri Voton/E+ via Getty Images

Joanna Fong-Isariyawongse, University of Pittsburgh

Investigations into the 1986 Space Shuttle Challenger disaster revealed that key decision-makers worked on little sleep, raising concerns that fatigue impaired their judgment. Similarly, in 1989, the Exxon Valdez oil spill resulted in a massive environmental catastrophe. The official investigation revealed the third mate, in charge of steering the ship, was running on too little sleep, among other problems.

While these specific disasters were not caused by daylight saving time, they are conclusively linked to fatigue, based on postaccident investigations and reports. They underscore the well-documented dangers of sleep deprivation and fatigue-related errors. Yet a vast body of research shows that every year, the shift to daylight saving time needlessly exacerbates these risks, disrupting millions of Americans’ sleep and increasing the likelihood of accidents, health issues and fatal errors.

Imagine a world where one simple decision – keeping our clocks aligned with the natural cycle of the Sun – could save lives, prevent accidents and improve mental well-being. It’s not just about an hour of lost sleep; it’s about how small disruptions ripple through our health, our workplaces and even our children’s futures.

I’m a neurologist who specializes in sleep health. I’ve seen firsthand the negative impacts of poor sleep; it has enormous personal and economic consequences.

Yet despite overwhelming research supporting better sleep policies – such as delaying school start times to align with adolescent biology and the adoption of permanent standard time – these issues remain largely overlooked in public policy discussions.

Sleep deprivation comes with real costs

Chronic sleep deprivation does more than leave people tired. It costs an estimated US$411 billion annually in lost productivity and health care costs. Poor sleep leads to workplace mistakes, car accidents and long-term health issues that strain businesses, families and the economy as a whole.

Fortunately, there’s a fix. Smarter sleep policies – such as permanent standard time and later school start times – can boost efficiency, improve health and save lives.

Advertisement
image 101376000 12222003
In a classroom setting, students take an exam.
Sleep-deprived teens have lower test scores and graduation rates. skynesher/E+

Up before dawn

Teenagers are the most sleep-deprived age group in the U.S. Multiple studies and surveys show that anywhere from 71% to 84% of high school students report getting insufficient sleep.

This is largely due to early school start times, which force teens to wake up before their biological clocks are ready. If you have a teenager, you probably see it every day: The teen struggling to wake up before sunrise, rushing out the door without breakfast, then waiting in the dark for the school bus.

More than 80% of public middle and high schools in the U.S. start before 8:30 a.m., with 42% starting before 8 a.m. and 10% before 7:30 a.m. As a result, some districts have bus pickups as early as 5 a.m.

Teenagers are going through a natural shift in their circadian rhythms by about two hours. This shift, driven by hormones and biology, makes it hard for them to fall asleep before around 11 p.m. The bodies of teens aren’t wired for these schedules, yet schools and society have designed a system that forces them to function at their worst.

Declining scores, drowsy driving and depression

Sleep-deprived teens have lower grades and test scores, more car crashes caused by drowsy driving, more alcohol and drug use and higher rates of depression, anxiety suicide and aggressive behavior, including carrying weapons.

Along with the health benefits, studies have found that moving school start times to 8:30 am or later could add $8.6 billion to the economy within two years, partly by increased graduation rates.

While concerns about increased transportation costs exist, such as the need for additional buses or drivers due to staggered school start times, some districts have found that optimizing bus routes can offset expenses, making the change cost-neutral or even cost-saving. For instance, a study in Boston found that reorganizing bus schedules using advanced algorithms reduced the number of buses needed and improved efficiency, which allowed high school students to start later and better align with their natural sleep cycles. This change not only supported adolescent sleep health but also saved the district $5 million annually. https://www.youtube.com/embed/OR6il9otpqM?wmode=transparent&start=0 Studies show that daylight saving time does not reduce energy use.

More heart attacks, car wrecks and suicide

Every March, most Americans shift their clocks forward for daylight saving time. Studies show this change disrupts sleep and leads to measurable adverse outcomes, including a significant increase in heart attacks. These effects linger for days after the shift, as sleep-deprived workers struggle to adjust.

Advertisement
image 101376000 12222003

The mental health impact is also severe. Suicide rates increase in the weeks following the switch, particularly for those already vulnerable to depression.

Unlike daylight saving time, standard time follows the body’s natural circadian rhythm, which is primarily regulated by exposure to sunlight. Our internal clocks are most stable when morning light exposure occurs early in the day, signaling the body to wake up and regulate key biological functions such as hormone production, alertness and metabolism. In contrast, daylight saving time artificially extends evening light, delaying the body’s release of melatonin and making it harder to fall asleep at a biologically appropriate time.

Studies have found that adopting permanent standard time could prevent up to 5,000 suicides annually by reducing seasonal depression, decrease errors, injuries and absenteeism in the workplace and make roads safer, potentially preventing 1,300 traffic deaths each year.

Times are changing

The U.S. tried permanent daylight saving time in 1974. It was so unpopular that Congress repealed it within nine months.

Russia tried it too, in 2011, but switched back three years later. The United Kingdom dropped permanent daylight saving time in 1971 after three years, and Portugal in 1996 after four. All of these countries found that the switch caused widespread public dissatisfaction, health concerns, more morning car accidents and disrupted work schedules. No country is currently on year-round daylight saving time.

These examples provide real-world evidence that permanent DST is undesirable due to public dissatisfaction, safety concerns and negative health effects – all three countries attempted it and ultimately reversed course. Since 2022, there has been renewed debate, largely driven by former U.S. Sen. Marco Rubio’s Sunshine Protection Act, which aims to make DST permanent.

However, the name is misleading because it doesn’t “protect” sunshine but rather eliminates critical morning light, which is essential for regulating circadian rhythms. Major health organizations, along with the National Safety Council, strongly oppose permanent DST due to its well-documented risks.

Advertisement
image 101376000 12222003

There are signs that suggest the U.S. is finally waking up to these problems. Out of 13,000 school districts, 1,000 have independently adopted later school start times. California and Florida have enacted laws requiring high schools to start no earlier than 8:30 a.m. California’s mandate went into effect in 2022, and Florida’s is set to begin in 2026.

Permanent standard time and later school start times are not radical ideas. They’re practical, evidence-based solutions based on human biology. Implementing these changes nationally would require congressional action. However, current federal law already allows states to adopt permanent standard time, as Arizona and Hawaii have done, setting a precedent for the rest of the country.

Joanna Fong-Isariyawongse, Associate Professor of Neurology, University of Pittsburgh

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Want more stories 👋
“Your morning jolt of Inspiring & Interesting Stories!”

Sign up to receive awesome articles directly to your inbox.

We don’t spam! Read our privacy policy for more info.

STM Coffee Newsletter 1
Advertisement
image 101376000 12222003

Discover more from Daily News

Subscribe to get the latest posts sent to your email.

Continue Reading

health and wellness

Urban Remedy Disrupts the $5.1B Shakes Market with First-of-Its-Kind Organic Protein Collagen Shake

Published

on

Made with 30g protein, 10g grass fed collagen and 0g added sugar.

POINT RICHMOND, Calif. /PRNewswire/ — Urban Remedy, a leader in certified organic freshly prepared ready-to-eat meals, snacks, and cold-pressed juices, announces its launch of organic high protein collagen meal replacement shakes.  Fueled by surging consumer demand for clean protein and collagen, Urban Remedy‘s decision to launch this trendsetting innovation is made possible with a first to market source of organic bovine collagen peptides from sustainably raised grass-fed cowhides.

Urban Remedy,
Urban Remedy Chocolate and Vanilla Protein Collagen Shakes

Now available in Whole Foods Market, the Organic Protein Collagen Shakes come in two delicious flavors that deliver unmatched nutritional benefits, Chocolate with 30g of protein, and Vanilla with 28g of protein. They both include 10g of organic collagen to support hair, skin, nail and joint health. The type 1 and type 3 collagen peptides are hydrolyzed for optimal absorption and provide 18 amino acids. There is 0g added sugar per bottle. Instead, the drinks are naturally sweetened with date, plant-based stevia extract and monk fruit extract offering an uncompromisingly delicious taste.

“The demand for high protein and clean eating continues to grow, fueled by busy lifestyles and an increasing understanding that food is medicine.” said Steven Naccarato, CEO, Urban Remedy. “As a fast-growing leader in functional food and beverage, we’re committed to transforming the way people fuel their bodies.”

“Consumers want foods that taste amazing with less sugar and real, nutrient dense ingredients,” said Neka Pasquale, Founder and Chief Product Officer of Urban Remedy. “Our products are 100% clean, and we specially choose certified organic ingredients for their healing properties, such as organic grass-fed collagen. As a brand we never include inflammatory ingredients like dairy, gluten, refined sugar or any artificial ingredients.”

The Organic Protein Collagen Shakes are now available in Urban Remedy’s grab & go kiosks in Whole Foods Market, online on Whole Foods Market on Amazon and retail for $9.99 for a 16oz bottle.  

For more information about Urban Remedy, visit www.urbanremedy.com.  Find a store near you at ww.urbanremedy.com/locations/

About Urban Remedy

Urban Remedy creates delicious, clean and convenient organic foods that embody the belief that food is healing. All of Urban Remedy‘s freshly prepared meals, refrigerated snacks and cold-pressed juices are certified organic, non-GMO, gluten-free, dairy-free, and refined sugar free to support an anti-inflammatory diet and are thoughtfully crafted with every ingredient chosen for its healing properties. Urban Remedy believes that business can be a force for good and is a certified B corporation meeting rigorous standards of environmental and social performance, accountability and transparency. Urban Remedy is sold in over 370 Whole Foods Market locations and in other retailers including Ralphs, Fred Meyer, QFC, Fry’s, King Soopers, Andronico’s, Raley’s and more. www.urbanremedy.com.

Advertisement
image 101376000 12222003

Source: SPINS MULO + Natural Channel, Protein & Meal Replacement Liquid Subcategory, L52W ending 1/26/25

SOURCE Urban Remedy


Discover more from Daily News

Subscribe to get the latest posts sent to your email.

Continue Reading

The Bridge

Celebrating the Legacy of Dr. Patricia Era Bath: A Trailblazer in Ophthalmology and Beyond

Published

on

In a world where innovation often shapes the future, few have left as profound a mark as Dr. Patricia Era Bath. Born on November 4, 1942, Dr. Bath transcended boundaries, redefining what it means to be a pioneer in medicine and a champion for the underserved. Her journey is not just a testament to her incredible intellect and skill as an ophthalmologist, but also to her unwavering commitment to humanitarianism and social justice.

Patricia Bath
Changing the face of Medicine (Wikipedia)

A Visionary in Ophthalmology

Dr. Bath was not only a skilled surgeon; she was a revolutionary. As one of the early pioneers of laser cataract surgery, her work has changed the lives of countless individuals worldwide. The development of this innovative technique not only improved patient outcomes but also symbolized a turning point in ophthalmic surgery. With her groundbreaking achievements, Dr. Bath illustrated that the intersection of science and compassion could embody the essence of healthcare.

Her trailblazing career included being the first woman inducted as a member of the prestigious Jules Stein Eye Institute and the first woman to lead a post-graduate training program in ophthalmology. Moreover, her remarkable journey culminated in her becoming the first African-American woman on the staff at the UCLA Medical Center, where she pushed boundaries in a field historically dominated by men.


A Legacy of Firsts

Dr. Bath’s legacy is marked by her groundbreaking “firsts.” She was the first African-American person to complete residency in ophthalmology at New York University and the first African-American woman to serve as a surgeon at UCLA Medical Center. Even more impressive is her achievement of becoming the first African-American woman doctor to receive a patent for a medical invention, holding five patents in total.

Among her most notable contributions is the founding of the American Institute for the Prevention of Blindness in Washington, D.C., where she tirelessly worked to raise awareness and address disparities in access to eye care. Dr. Bath’s pioneering spirit extended beyond her profession; she propelled an entire generation toward a future where access to quality medical treatment is a right, not a privilege.

A Voice for the Voiceless

Dr. Bath’s humanitarian work extended to advocacy as she sought to illuminate the challenges faced by marginalized communities in achieving equitable healthcare. In 2009, she was honored to stand beside President Barack Obama, recognizing her contributions in ophthalmology and serving on his commission for digital accessibility to blind children. Her efforts highlighted the pressing need for inclusivity in healthcare, technology, and education—echoing her steadfast belief that everyone deserves access to the tools that enhance sight and learning.

In April 2019, just weeks before her passing, Dr. Bath shared her insights during a Senate hearing titled “Trailblazers and Lost Einsteins: Women Inventors and the Future of American Innovation.” Her testimony shed light on the gender disparities in STEM fields and the crucial need for recognition and support of female inventors. Even in her final days, she was a beacon of hope and progress.

Advertisement
image 101376000 12222003

Remembering Dr. Patricia Bath

Dr. Patricia Era Bath passed away on May 30, 2019, due to cancer-related complications, leaving behind an inspiring legacy of resilience, empathy, and innovation. At age 76, she had changed the very fabric of medicine while reminding us of the vital importance of diversity in healthcare.

As we celebrate Dr. Bath’s life, let us remember her not only for her remarkable achievements but also for the path she has paved for future generations. Her legacy lives on, reminding us that the fight for equity in healthcare is far from over and that the spirit of innovation fuels our collective journey toward progress.

In honor of Dr. Bath, let us continue her mission to advance healthcare for all, celebrate diversity in all its forms, and strive to make the world a more equitable place—for sight, for education, and for justice. Rest in peace, Dr. Patricia Era Bath. Your vision changed the world, and you will forever be remembered as a true trailblazer.

Patricia Bath (Wikipedia) https://en.wikipedia.org/wiki/Patricia_Bath

STM Daily News is a vibrant news blog dedicated to sharing the brighter side of human experiences. Emphasizing positive, uplifting stories, the site focuses on delivering inspiring, informative, and well-researched content. With a commitment to accurate, fair, and responsible journalism, STM Daily News aims to foster a community of readers passionate about positive change and engaged in meaningful conversations. Join the movement and explore stories that celebrate the positive impacts shaping our world.

https://stmdailynews.com/

Advertisement
image 101376000 12222003

Discover more from Daily News

Subscribe to get the latest posts sent to your email.

Continue Reading

Trending